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GNC Herbal Plus® Black Cohosh Extract 40mg

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Item #197012 See Product Details

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Description
Herbal Supplement
Support for Menopause*
Vegetarian Standardized Extract

For more information about Whole Herbs Vs. Extracts,

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

As a dietary supplement, take one capsule daily.

Serving Size 1 Capsule
Servings Per Container 100
Amount Per Serving % DV
Black Cohosh Root Extract (Cimicifuga racemosa) (2.5% Triterpene glycosides = 1 mg) 40.00 mg **
** Daily Value (DV) not established

Other Ingredients: Cellulose, Vegetable Cellulose Capsule

No Sugar, No Artificial Colors, No Artificial Flavors, Sodium Free, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.

Storage Instructions: Store in a cool dry place.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

Distributed by:
General Nutrition Corporation
Pittsburgh, PA 15222

Health Notes

Black Cohosh

Black Cohosh
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Menopause
Dose: 20 mg of a highly concentrated herbal extract taken twice per day
Studies have shown black cohosh to be a safe and effective treatment for women with hot flashes associated with menopause.(more)
Menopause and Depression
Dose: Two tablets twice a day for 8 weeks, then one tablet twice a day for 8 weeks, each tablet supplying 1 mg of triterpene glycosides from black cohosh and 0.25 mg of hypericin from St. John's wort
Menopausal and depression symptoms improved in post-menopausal women after they took a combination of black cohosh and St. John's wort. (more)
Dysmenorrhea
Dose: Refer to label instructions
Black cohosh has a history as a folk medicine for relieving menstrual cramps.(more)
Premenstrual Syndrome
Dose: Refer to label instructions
Black cohosh has been historically used to treat PMS.(more)
Menopause
Dose: 20 mg of a highly concentrated herbal extract taken twice per day
Studies have shown black cohosh to be a safe and effective treatment for women with hot flashes associated with menopause.(more)
Menopause and Depression
Dose: Two tablets twice a day for 8 weeks, then one tablet twice a day for 8 weeks, each tablet supplying 1 mg of triterpene glycosides from black cohosh and 0.25 mg of hypericin from St. John's wort
Menopausal and depression symptoms improved in post-menopausal women after they took a combination of black cohosh and St. John's wort. (more)
Dysmenorrhea
Dose: Refer to label instructions
Black cohosh has a history as a folk medicine for relieving menstrual cramps.(more)
Premenstrual Syndrome
Dose: Refer to label instructions
Black cohosh has been historically used to treat PMS.(more)
Osteoporosis
Dose: Refer to label instructions
Black cohosh has been shown to improve bone mineral density in animals fed a low-calcium diet.(more)
Menopause
Dose: 20 mg of a highly concentrated herbal extract taken twice per day

Some, but not all, double-blind trials support the usefulness of black cohosh for women with hot flashes associated with menopause.1 In a three-month study of postmenopausal women, 40 mg per day of an extract of black cohosh was as effective as estrogen therapy in the treatment of hot flashes.2 A review of eight trials concluded black cohosh to be both safe and effective.3 However, one double-blind trial found that black cohosh is ineffective as a treatment for menopausal symptoms.4 Many doctors recommend 20 mg of a highly concentrated extract taken twice per day; 2 to 4 ml of tincture three times per day may also be used.

In a double-blind study of postmenopausal women who were experiencing psychological symptoms, a combination of black cohosh and St. John's wort was significantly more effective than a placebo in improving both menopausal symptoms and depression. The product used in this study contained (per tablet) black cohosh standardized to 1 mg of triterpene glycosides and St. John's wort standardized to 0.25 mg of hypericin. The amount taken was two tablets twice a day for eight weeks, followed by one tablet twice a day for eight weeks.5

References

1. Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecological disorders. Advances Therapy 1998;15:45-53.

2. Nappi RE, Malavasi B, Brundu B, Facchinetti F. Efficacy of Cimicifuga racemosa on climacteric complaints: a randomized study versus low-dose transdermal estradiol. Gynecol Endocrinol 2005;20:30-5.

3. Lieberman S. A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause. J Womens Health 1998;7:525-9.

4. Newton KM, Reed SD, LaCroix AZ, et al. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med 2006;145:869-79.

5. Uebelhack R, Blohmer JU, Graubaum HJ, et al. Black cohosh and St. John's wort for climacteric complaints: a randomized trial. Obstet Gynecol 2006;107:247-55.

Menopause and Depression
Dose: Two tablets twice a day for 8 weeks, then one tablet twice a day for 8 weeks, each tablet supplying 1 mg of triterpene glycosides from black cohosh and 0.25 mg of hypericin from St. John's wort In a double-blind study of postmenopausal women who were experiencing psychological symptoms, a combination of black cohosh and St. John's wort was significantly more effective than a placebo in improving both menopausal symptoms and depression. The product used in this study contained (per tablet) black cohosh standardized to 1 mg of triterpene glycosides and St. John's wort standardized to 0.25 mg of hypericin. The amount taken was two tablets twice a day for eight weeks, followed by one tablet twice a day for eight weeks.1
References

1. Uebelhack R, Blohmer JU, Graubaum HJ, et al. Black cohosh and St. John's wort for climacteric complaints: a randomized trial. Obstet Gynecol 2006;107:247-55.

Dysmenorrhea
Dose: Refer to label instructions

Black cohosh has a history as a folk medicine for relieving menstrual cramps. Black cohosh can be taken in several forms, including crude plant, dried root, or rhizome (300-2,000 mg per day), or as a solid, dry powdered extract (250 mg three times per day). Standardized extracts of the herb are available, though they have primarily been researched for use with menopausal women suffering from hot flashes. The recommended amount is 20-40 mg twice per day.1 The best researched form provides 1 mg of deoxyactein per 20 mg of extract. Tinctures can are also used (2-4 ml three times per day).2 The Commission E Monograph recommends black cohosh be taken for up to six months, and then discontinued.3

References

1. Murray MT. The Healing Power of Herbs. Rocklin, CA: Prima Publishing, 1995, 376.

2. Bradley PR, ed. British Herbal Compendium, vol 1. Bournemouth, Dorset, UK: British Herbal Medicine Association, 1992, 34-6.

3. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 90.

Premenstrual Syndrome
Dose: Refer to label instructions

Black cohosh is approved in Germany for use in women with PMS.1 This approval appears to be based on historical use as there are no modern clinical trials to support the use of black cohosh for PMS.

References

1. Blumenthal M, Busse WR, Goldberg A, et al., eds. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 90.

Menopause
Dose: 20 mg of a highly concentrated herbal extract taken twice per day

Some, but not all, double-blind trials support the usefulness of black cohosh for women with hot flashes associated with menopause.1 In a three-month study of postmenopausal women, 40 mg per day of an extract of black cohosh was as effective as estrogen therapy in the treatment of hot flashes.2 A review of eight trials concluded black cohosh to be both safe and effective.3 However, one double-blind trial found that black cohosh is ineffective as a treatment for menopausal symptoms.4 Many doctors recommend 20 mg of a highly concentrated extract taken twice per day; 2 to 4 ml of tincture three times per day may also be used.

In a double-blind study of postmenopausal women who were experiencing psychological symptoms, a combination of black cohosh and St. John's wort was significantly more effective than a placebo in improving both menopausal symptoms and depression. The product used in this study contained (per tablet) black cohosh standardized to 1 mg of triterpene glycosides and St. John's wort standardized to 0.25 mg of hypericin. The amount taken was two tablets twice a day for eight weeks, followed by one tablet twice a day for eight weeks.5

References

1. Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecological disorders. Advances Therapy 1998;15:45-53.

2. Nappi RE, Malavasi B, Brundu B, Facchinetti F. Efficacy of Cimicifuga racemosa on climacteric complaints: a randomized study versus low-dose transdermal estradiol. Gynecol Endocrinol 2005;20:30-5.

3. Lieberman S. A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause. J Womens Health 1998;7:525-9.

4. Newton KM, Reed SD, LaCroix AZ, et al. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med 2006;145:869-79.

5. Uebelhack R, Blohmer JU, Graubaum HJ, et al. Black cohosh and St. John's wort for climacteric complaints: a randomized trial. Obstet Gynecol 2006;107:247-55.

Menopause and Depression
Dose: Two tablets twice a day for 8 weeks, then one tablet twice a day for 8 weeks, each tablet supplying 1 mg of triterpene glycosides from black cohosh and 0.25 mg of hypericin from St. John's wort In a double-blind study of postmenopausal women who were experiencing psychological symptoms, a combination of black cohosh and St. John's wort was significantly more effective than a placebo in improving both menopausal symptoms and depression. The product used in this study contained (per tablet) black cohosh standardized to 1 mg of triterpene glycosides and St. John's wort standardized to 0.25 mg of hypericin. The amount taken was two tablets twice a day for eight weeks, followed by one tablet twice a day for eight weeks.1
References

1. Uebelhack R, Blohmer JU, Graubaum HJ, et al. Black cohosh and St. John's wort for climacteric complaints: a randomized trial. Obstet Gynecol 2006;107:247-55.

Dysmenorrhea
Dose: Refer to label instructions

Black cohosh has a history as a folk medicine for relieving menstrual cramps. Black cohosh can be taken in several forms, including crude plant, dried root, or rhizome (300-2,000 mg per day), or as a solid, dry powdered extract (250 mg three times per day). Standardized extracts of the herb are available, though they have primarily been researched for use with menopausal women suffering from hot flashes. The recommended amount is 20-40 mg twice per day.1 The best researched form provides 1 mg of deoxyactein per 20 mg of extract. Tinctures can are also used (2-4 ml three times per day).2 The Commission E Monograph recommends black cohosh be taken for up to six months, and then discontinued.3

References

1. Murray MT. The Healing Power of Herbs. Rocklin, CA: Prima Publishing, 1995, 376.

2. Bradley PR, ed. British Herbal Compendium, vol 1. Bournemouth, Dorset, UK: British Herbal Medicine Association, 1992, 34-6.

3. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 90.

Premenstrual Syndrome
Dose: Refer to label instructions

Black cohosh is approved in Germany for use in women with PMS.1 This approval appears to be based on historical use as there are no modern clinical trials to support the use of black cohosh for PMS.

References

1. Blumenthal M, Busse WR, Goldberg A, et al., eds. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 90.

Osteoporosis
Dose: Refer to label instructions

Black cohosh has been shown to improve bone mineral density in animals fed a low calcium diet,1 but it has not been studied for this purpose in humans.

References

1. Kadota S, Li JX, Li HY, et al. Effects of cimicifugae rhizome on serum calcium and phosphate levels in low calcium dietary rats and on bone mineral density in ovariectomized rats. Phytomed 1996/97;3(4):379-85.

Parts Used & Where Grown

Black cohosh is a shrub-like plant native to the eastern deciduous forests of North America, ranging from southern Ontario to Georgia, north to Wisconsin and west to Arkansas. The dried root and rhizome are used medicinally.1 When harvested from the wild, the root is black in color. Cohosh, an Algonquin Indian word meaning "rough," refers to the plants gnarly root structure.2

Copyright 2015 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2016.

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