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GNC Herbal PlusŪ Feverfew Extract 380mg
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For General Well-Being*
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- Supplement Facts
As a dietary supplement, take one to two capsule daily.
Serving Size 1 Capsule Servings Per Container 100 Amount Per Serving % DV Feverfew Flower Extract (Tanacetum parthenium) (0.2% Parthenolides - 0.76mg) 380.00 mg ** ** Daily Value (DV) not established
Other Ingredients: Cellulose, Vegetable Cellulose Capsule
No Sugar, No Artificial Colors, No Artificial Flavors, Sodium Free, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.
Warning: Consult your physician prior to using this product if you are pregnant, nursing or taking medication, or have a medical condition. Discontinue use two weeks prior to surgery. KEEP OUT OF REACH OF CHILDREN.
Distributed by: General Nutrition Corporation Pittsburgh, PA 15222
- Health Notes
FeverfewFeverfewThis nutrient has been used in connection with the following health goals
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
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This supplement has been used in connection with the following health conditions:Migraine HeadacheDose: Standardized herbal extract delivering 250 mcg of parthenolide per dayFeverfew is the most frequently used herb for the long-term migraine prevention. Continuous use of feverfew may reduce the severity, duration, and frequency of migraine headaches.(more)Migraine HeadacheDose: Standardized herbal extract delivering 250 mcg of parthenolide per day
The most frequently used herb for the long-term prevention of migraines is feverfew.1 Four double-blind trials have reported that continuous use of feverfew leads to a reduction in the severity, duration, and frequency of migraine headaches,2, 3, 4, 5 although one double-blind trial found feverfew to be ineffective.6
Studies suggest that taking standardized feverfew leaf extracts that supply a minimum of 250 mcg of parthenolide per day is most effective. Results may not be evident for at least four to six weeks. Although there has been recent debate about the relevance of parthenolide as an active constituent,7 it is best to use standardized extracts of feverfew until research proves otherwise.
A double-blind study found that a combination of feverfew and ginger may be effective for acute treatment of migraines. In that study, 63% of patients taking the herbal preparation experienced pain relief within 2 hours, whereas only 39% taking placebo experienced relief, a statistically significant difference. The product used in this study was a proprietary preparation called LipiGesic M (PuraMed BioScience, Inc., Schofield, WI). The liquid from 1-unit dose applicator was administered sublingually, held under the tongue for 60 seconds, and then swallowed. A second dose was given 5 minutes later. If pain persisted after 1 hour, a second treatment of 2-unit doses could be given.8References
1. Volger BK, Pittler MH, Ernst E. Feverfew as a preventive treatment for migraine: a systematic review. Cephalagia 1998;18:704-8.
2. Murphy JJ, Hepinstall S, Mitchell JR. Randomized double-blind placebo controlled trial of feverfew in migraine prevention. Lancet 1988;2:189-92.
3. Johnson ES, Kadam NP, Hylands DM, Hylands PJ. Efficacy of feverfew as prophylactic treatment of migraine. Br Med J (Clin Res Ed) 1985;291:569-73.
4. Palevitch D, Earon G, Carasso R. Feverfew (Tanacetum parthenium) as a prophylactic treatment for migraine: A double-blind placebo-controlled study. Phytother Res 1997;11:508-11.
5. Diener HC, Pfaffenrath V, Schnitker J, et al. Efficacy and safety of 6.25 mg t.i.d. feverfew CO2-extract (MIG-99) in migraine prevention - a randomized, double-blind, multicentre, placebo-controlled study. Cephalalgia2005;25:1031-41.
6. De Weerdt CJ, Bootsma HPR, Hendriks H. Herbal medicines in migraine prevention. Phytomed 1996;3:225-30.
7. Awang DVC. Parthenolide: The demise of a facile theory of feverfew activity. J Herbs Spices Medicinal Plants 1998;5:95-8.
8. Cady RK, Goldstein J, Nett R, et al. A double-blind placebo-controlled pilot study of sublingual feverfew and ginger (LipiGesic M) in the treatment of migraine. Headache 2011;51:1078-86
Parts Used & Where Grown
Feverfew grows widely across Europe and North America. The leaves are used in herbal medicine.
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.
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