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GNC Herbal Plus® Horse Chestnut Extract 300mg

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100 Capsules

Item #196412 See Product Details

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Description
Herbal Supplement
Supports Healthy Leg Vein Circulation*
Vegetarian Standardized Extract
Supplement Facts

As a dietary supplement, take one to four capsules daily.

Serving Size 1 Capsule
Servings Per Container 100
Amount Per Serving % DV
Horse Chestnut Seed Extract (Aesculus hippocastanum)(20% Aescin = 60mg) 300.00 mg **
** Daily Value (DV) not established

Other Ingredients: Cellulose, Vegetable Cellulose Capsule

No Sugar, No Artificial Colors, No Artificial Flavors, Sodium Free, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.

Storage Instructions: Store in a cool dry place.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

Distributed by:
General Nutrition Corporation
Pittsburgh, PA 15222

Health Notes

Horse Chestnut

Horse Chestnut
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Sprains and Strains
Dose: Apply a 2% gel every two hours
Horse chestnut contains a compound called aescin that acts as an anti-inflammatory and reduces edema (swelling with fluid) following injuries.(more)
Hemorrhoids
Dose: Take a standardized herbal extract providing 90 to 150 mg aescin daily
Horse chestnut extracts have been reported to reduce hemorrhoid symptoms.(more)
Wound Healing
Dose: Apply topically
Horse chestnut contains a compound called aescin that acts as an anti-inflammatory and reduces swelling after trauma, particularly sports injuries, surgery, and head injury.(more)
Wound Healing
Dose: Apply topically
Horse chestnut contains a compound called aescin that acts as an anti-inflammatory and reduces swelling after trauma, particularly sports injuries, surgery, and head injury.(more)
Chronic Venous Insufficiency
Dose: Standardized extract providing 50 mg aescin two to three times per day
Horse chestnut is traditionally used for venous problems, and its effectiveness has been backed up by an extensive overview of clinical trials.(more)
Varicose Veins
Dose: Refer to label instructions
Horse chestnut seed extract can be taken orally or applied topically treat varicose veins.(more)
Edema
Dose: Refer to label instructions
An ingredient in horse chestnut seed has been shown to effectively reduce post-surgical edema in preliminary trials.(more)
Sprains and Strains
Dose: Apply a 2% gel every two hours

Horse chestnut contains a compound called aescin that acts as an anti-inflammatory and reduces edema (swelling with fluid) following trauma, particularly sports injuries, surgery, and head injury.1 A topical gel containing 2% of the compound aescin found in horse chestnut is widely used in Germany to treat minor sports injuries, including sprains and strains.2 The gel is typically applied to affected area every two hours until swelling begins to subside.

References

1. Guillaume M, Padioleau F. Veinotonic effect, vascular protection, anti-inflammatory and free radical scavenging properties of horse chestnut extract. Arzneimittelforschung 1994;44:25-35.

2. Pabst H. Kleine MW. Prevention and therapy of sports injuries. Experiences with an escin-containing gel. Fortschr Med 1986;104:44-6.

Hemorrhoids
Dose: Take a standardized herbal extract providing 90 to 150 mg aescin daily

Horse chestnut extracts have been reported from a double-blind trial to reduce symptoms of hemorrhoids.1 Some doctors recommend taking horse chestnut seed extracts standardized for aescin (also known as escin) content (16-21%), or an isolated aescin preparation, providing 90 to 150 mg of aescin per day.

References

1. Nini G, Di Cicco CO. Controlled clinical evaluation of a new anti-hemorrhoid drug, using a completely randomized experimental plan. Clin Ther 1978;86:545-59 [in Italian].

Wound Healing
Dose: Apply topically

Horse chestnut contains a compound called aescin that acts as an anti-inflammatory and reduces edema (swelling with fluid) following trauma, particularly sports injuries, surgery, and head injury.1 A topical aescin preparation is popular in Europe for the treatment of acute sprains during sporting events.

References

1. Guillaume M, Padioleau F. Veinotonic effect, vascular protection, anti-inflammatory and free radical scavenging properties of horse chestnut extract. Arzneimittelforschung 1994;44:25-35.

Wound Healing
Dose: Apply topically

Horse chestnut contains a compound called aescin that acts as an anti-inflammatory and reduces edema (swelling with fluid) following trauma, particularly sports injuries, surgery, and head injury.1 A topical aescin preparation is popular in Europe for the treatment of acute sprains during sporting events.

References

1. Guillaume M, Padioleau F. Veinotonic effect, vascular protection, anti-inflammatory and free radical scavenging properties of horse chestnut extract. Arzneimittelforschung 1994;44:25-35.

Chronic Venous Insufficiency
Dose: Standardized extract providing 50 mg aescin two to three times per day

According to an extensive overview of clinical trials, standardized horse chestnut seed extract, which contains the active compound aescin, has been shown to be effective in double-blind and other controlled research, supporting the traditional use of horse chestnut for venous problems.1 In these trials, capsules of horse chestnut extract containing 50 mg of aescin were given two to three times daily for CVI. The positive effect results in part from horse chestnut's ability to strengthen capillaries, which leads to a reduction in swelling.2

References

1. Pittler MH, Ernst E. Horse-chestnut seed extract for chronic venous insufficiency: a criteria-based systematic review. Arch Dermatol 1998;134:1356-60.

2. Bisler H, Pfeifer R, Kluken N, Pauschinger P. Effects of horse-chestnut seed extract on transcapillary filtration in chronic venous insufficiency. Deutche Med Wochenschr 1986;111:1321-9 [in German].

Varicose Veins
Dose: Refer to label instructions

Horse chestnut seed extract can be taken orally or used as an external application for disorders of venous circulation, including varicose veins.1 Preliminary studies in humans have shown that 300 mg three times per day of a standardized extract of horse chestnut seed reduced the formation of enzymes thought to cause varicose veins.2 Topical gel or creams containing 2% aescin can be applied topically three or four time per day to the affected limb(s).

References

1. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin, TX: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 149.

2. Kreysel HW, Nissen HP, Enghofer E. A possible role of lysosomal enzymes in the pathogenesis of varicosis and the reduction in their serum activity by Venostasin. Vasa 1983;12:377-82.

Edema
Dose: Refer to label instructions

Aescin, isolated from horse chestnut seed, has been shown to effectively reduce post-surgical edema in preliminary trials.1, 2 A form of aescin that is injected into the bloodstream is often used but only under the supervision of a qualified healthcare professional.

References

1. Dini D, Bianchini M, Massa T, Fassio T. Treatment of upper limb lymphedema after mastectomy with escine and levo-thyroxine. Minerva Med 1981;72:2319-22 [in Italian].

2. Wilhelm K, Feldmeier C. Thermometric investigations about the efficacy of beta-escin to reduce postoperative edema. Med Klin 1977;72:128-34 [in German].

Parts Used & Where Grown

The horse chestnut tree is native to Asia and northern Greece, but it is now cultivated in many areas of Europe and North America. The tree produces fruits that are made up of a spiny capsule containing one to three large seeds, known as horse chestnuts. Traditionally, many of the aerial parts of the horse chestnut tree, including the seeds, leaves, and bark, were used in medicinal preparations. Modern extracts of horse chestnut are usually made from the seeds, which are high in the active constituent aescin (also known as escin).

Copyright 2015 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2016.

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