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GNC Herbal PlusŪ Yohimbe Extract 450 MG

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100 Capsules

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Description
Tradional Male Herb

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

As a dietary supplement, take one capsule at least one hour before activity.

Serving Size 1 Capsule
Servings Per Container 100
Amount Per Serving % DV
Yohimbe Bark Extract (Pausinystalia yohima)(2% Yohimbine alkaloids= 9 mg) 450.00 mg **
** Daily Value (DV) not established

Other Ingredients: Maltodextrin, Vegetarian Cellulose Capsule, Cellulose

No Sugar, No Artificial Colors, No Artificial Flavors, Sodium Free, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.

Warning: Use only as directed. Do not exceed recommended daily intake. Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.

Distributed by: General Nutrition Corporation Pittsburgh, PA 15222

Health Notes

Yohimbe

Yohimbe
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Erectile Dysfunction
Dose: 5 to 10 drops three times per day, under a doctor's supervision
Yohimbe appears to increase blood flow and dilate blood vessels.(more)
Erectile Dysfunction
Dose: 5 to 10 drops three times per day, under a doctor's supervision
Yohimbe appears to increase blood flow and dilate blood vessels.(more)
Obesity
Dose: Take under medical supervision: enough to supply 5 mg of yohimbine four times per day
Yohimbine, a chemical found in yohimbe bark, may help weight loss by raising metabolic rate, reducing appetite, and increasing fat burning.(more)
Athletic Performance
Dose: Refer to label instructions
Yohimbine has shown an ability to stimulate the nervous system, promote the release of fat from fat cells, and affect the cardiovascular system.(more)
Erectile Dysfunction
Dose: 5 to 10 drops three times per day, under a doctor's supervision

Yohimbine (the primary active constituent in yohimbe) has been shown in several double-blind trials to help treat men with ED;1, 2 negative results have also been reported, however.3, 4 Yohimbe dilates blood vessels and may help, regardless of the cause of ED. A tincture of yohimbe bark is often used in the amount of 5 to 10 drops three times per day. Standardized yohimbe extracts are also available. A typical daily amount of yohimbine is 15 to 30 mg. It is best to use yohimbe and yohimbine under the supervision of a physician.

References

1. Ernst E, Pittler MH. Yohimbine for erectile dysfunction: A systematic review and meta-analysis of randomized clinical trials. J Urol 1998;159:433-6.

2. Carey MP, Johnson BT. Effectiveness of yohimbine in the treatment of erectile disorder: Four meta-analytic integrations. Arch Sex Behav 1996;25:341.

3. Kunelius P, Hakkinen J, Lukkarinen O. Is high-dose yohimbine hydrochloride effective in the treatment of mixed-type impotence? A prospective, randomized, controlled double-blind crossover study. Urol 1997;49:441-4.

4. Mann K, Klingler T, Noe S, et al. Effect of yohimbine on sexual experiences and nocturnal tumescence and rigidity in erectile dysfunction. Arch Sex Behav 1996;25:1-16.

Erectile Dysfunction
Dose: 5 to 10 drops three times per day, under a doctor's supervision

Yohimbine (the primary active constituent in yohimbe) has been shown in several double-blind trials to help treat men with ED;1, 2 negative results have also been reported, however.3, 4 Yohimbe dilates blood vessels and may help, regardless of the cause of ED. A tincture of yohimbe bark is often used in the amount of 5 to 10 drops three times per day. Standardized yohimbe extracts are also available. A typical daily amount of yohimbine is 15 to 30 mg. It is best to use yohimbe and yohimbine under the supervision of a physician.

References

1. Ernst E, Pittler MH. Yohimbine for erectile dysfunction: A systematic review and meta-analysis of randomized clinical trials. J Urol 1998;159:433-6.

2. Carey MP, Johnson BT. Effectiveness of yohimbine in the treatment of erectile disorder: Four meta-analytic integrations. Arch Sex Behav 1996;25:341.

3. Kunelius P, Hakkinen J, Lukkarinen O. Is high-dose yohimbine hydrochloride effective in the treatment of mixed-type impotence? A prospective, randomized, controlled double-blind crossover study. Urol 1997;49:441-4.

4. Mann K, Klingler T, Noe S, et al. Effect of yohimbine on sexual experiences and nocturnal tumescence and rigidity in erectile dysfunction. Arch Sex Behav 1996;25:1-16.

Obesity
Dose: Take under medical supervision: enough to supply 5 mg of yohimbine four times per day

The ability of yohimbine, a chemical found in yohimbe bark, to stimulate the nervous system, 1, 2 and to promote the release of fat from fat cells,3, 4 has led to claims that it might help weight loss by raising metabolic rate, reducing appetite, or increase fat burning. Although a preliminary trial found yohimbine ineffective for weight loss, a double-blind study found that women taking 5 mg of yohimbine four times per day along with a weight-loss diet lost significantly more weight than those taking a placebo with the same diet after three weeks.5 However, a similar study using 18 mg per day of yohimbine for eight weeks reported no benefit to weight loss compared with a placebo.6 A double-blind study of men who were not dieting reported no effect of up to 43 mg per day of yohimbine on weight or body composition after six months.7 All of these studies used pure yohimbine; no study has tested the effects of yohimbe herb on weight loss.

References

1. Mosqueda-Garcia R, Fernandez-Violante R, Tank J, et al. Yohimbine in neurally mediated syncope. Pathophysiological implications. J Clin Invest 1998;102:1824-30.

2. Goldberg MR, Robertson D. Yohimbine: a pharmacological probe for the study of the alpha 2-adrenoceptor. Pharmacol Rev 1983;35:143-180

3. Galitzky J, Taouis M, Berlan M, et al. Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers. Eur J Clin Invest 1988;18:587-94.

4. Zahorska-Markiewicz B, Kucio C, Piskorska D. Adrenergic control of lipolysis and metabolic responses in obesity. Horm Metab Res 1986;18:693-7.

5. Kucio C, Jonderko K, Piskorska D. Does yohimbine act as a slimming drug? Isr J Med Sci 1991;27:550-6.

6. Berlin I, Crespo-Laumonnier B, Turpin G, Puech AJ. The alpha-2 adrenoceptor antagonist yohimbine does not facilitate weight loss but blocks adrenaline induced platelet aggregation in obese subjects. Therapie 1989;44:301 [letter].

7. Sax L. Yohimbine does not affect fat distribution in men. Int J Obes 1991;15:561-5.

Athletic Performance
Dose: Refer to label instructions

The ability of yohimbine, a chemical found in yohimbe bark, to stimulate the nervous system,1, 2 promote the release of fat from fat cells,3, 4 and affect the cardiovascular system 5 has led to claims that yohimbe might help athletic performance or improve body composition. However, a double-blind study of men who were not dieting reported no effect of up to 43 mg per day of yohimbine on weight or body composition after six months.6 No research has tested yohimbe herb for effects on body composition, and no human research has investigated the ability of yohimbine or yohimbe to affect athletic performance. Other studies have determined that a safe daily amount of yohimbine is 15 to 30 mg.7 However, people with kidney disorders should not take yohimbe, and side effects of nausea, dizziness, or nervousness may occur that necessitate reducing or stopping yohimbe supplementation.

References

1. Mosqueda-Garcia R, Fernandez-Violante R, Tank J, et al. Yohimbine in neurally mediated syncope. Pathophysiological implications. J Clin Invest 1998;102:1824-30.

2. Goldberg MR, Robertson D. Yohimbine: a pharmacological probe for the study of the alpha 2-adrenoceptor. Pharmacol Rev 1983;35:143-180

3. Galitzky J, Taouis M, Berlan M, et al. Alpha 2-antagonist compounds and lipid mobilization: evidence for a lipid mobilizing effect of oral yohimbine in healthy male volunteers. Eur J Clin Invest 1988;18:587-94.

4. Zahorska-Markiewicz B, Kucio C, Piskorska D. Adrenergic control of lipolysis and metabolic responses in obesity. Horm Metab Res 1986;18:693-7.

5. Waluga M, Janusz M, Karpel E, et al. Cardiovascular effects of ephedrine, caffeine and yohimbine measured by thoracic electrical bioimpedance in obese women. Clin Physiol 1998;18:69-76.

6. Sax L. Yohimbine does not affect fat distribution in men. Int J Obes 1991;15:561-5.

7. Goldberg KA. Yohimbine in the treatment of male erectile sexual dysfunction-a clinical review. Today's Ther Trends J New Dev Clin Med 1996;14:25-33.

Parts Used & Where Grown

Yohimbe is a tall evergreen forest tree native to southwestern Nigeria, Cameroon, Gabon, and the Congo. The bark of this African tree is used medicinally. There are concerns, however, that the tree may be endangered due to over-harvesting for use as medicine.

Copyright 2014 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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