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GNC Potassium & Magnesium Aspartate

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240 Capsules

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Description
Helps regulate water balance and is necessary for normal nerve & muscle cell function*

Potassium is involved in the regulation of cellular water balance.* Magnesium is involved in nerve, skeletal muscle, heart and cell function.*

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

As a dietary supplement, take one capsule with a meal. For maximum support, take as directed every day.

Serving Size 1 Capsules
Servings Per Container 240
Amount Per Serving % DV
Monomagnesium Di-L-Aspartate 250.00 mg **
Monopotassium Aspartate 250.00 mg **
** Daily Value (DV) not established

Other Ingredients: Gelatin, Cellulose

No Sugar, No Artificial Colors, No Artificial Flavors, Sodium Free, No Wheat, No Gluten, No Corn, No Soy, No Dairy, Yeast Free.

Warning: KEEP OUT OF REACH OF CHILDREN

Distributed by: General Nutrition Corporation Pittsurgh, PA 15222

Health Notes

Potassium

Potassium
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Hypertension in People Not Taking Potassium-Sparing Diuretics
Dose: 2,400 mg per under a doctor's supervision
Potassium may be effective at lowering blood pressure, according to an analysis of trials.(more)
Congestive Heart Failure
Dose: Consult a qualified healthcare practitioner
Potassium can be beneficial for heart patients, but talk to your doctor first. Several drugs for CHF may cause potassium retention, making extra potassium dangerous.(more)
Stroke
Dose: Consult a qualified healthcare practitioner
(more)
Cardiac Arrhythmia
Dose: 1,000 mg daily under medical supervision
In one study, people taking hydrochlorothiazide for high blood pressure saw a significant reduction in arrhythmias when they supplemented with potassium.(more)
Premenstrual Syndrome
Dose: 600 mg daily
A preliminary trial found that women with severe PMS who took potassium supplements had complete resolution of PMS symptoms within four menstrual cycles.(more)
Premenstrual Syndrome
Dose: 600 mg daily
A preliminary trial found that women with severe PMS who took potassium supplements had complete resolution of PMS symptoms within four menstrual cycles.(more)
Chronic Fatigue Syndrome
Dose: 1 gram of aspartates is taken twice per day
Potassium-magnesium aspartate has shown benefits for chronically fatigued people in some trials.(more)
Hypertension in People Not Taking Potassium-Sparing Diuretics
Dose: 2,400 mg per under a doctor's supervision

Potassium supplements in the amount of at least 2,400 mg per day lower blood pressure, according to an analysis of 33 trials.1 However, potassium supplements greater than 100 mg per tablet require a prescription, and the low-dose potassium supplements available without a prescription can irritate the stomach if taken in large amounts. Moreover, some people, such as those taking potassium-sparing diuretics, should not take potassium supplements. Therefore, the use of potassium supplements for lowering blood pressure should only be done under the care of a doctor.

References

1. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure: meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32.

Congestive Heart Failure
Dose: Consult a qualified healthcare practitioner

Magnesium deficiency frequently occurs in people with CHF, and such a deficiency may lead to heart arrhythmias. Magnesium supplements have reduced the risk of these arrhythmias.1 People with CHF are often given drugs that deplete both magnesium and potassium; a deficiency of either of these minerals may lead to an arrhythmia.2 Many doctors suggest magnesium supplements of 300 mg per day.

Whole fruit and fruit and vegetable juice, which are high in potassium, are also recommended by some doctors. One study showed that elderly men who consumed food prepared with potassium-enriched salt (containing about half potassium chloride and half sodium chloride) had a 70% reduction in deaths due to heart failure and a significant reduction in medical costs for cardiovascular disease, when compared with men who continued to use regular salt.3 While increasing potassium intake can be beneficial for heart patients, this dietary change should be discussed with a healthcare provider, because several drugs given to people with CHF may actually cause retention of potassium, making dietary potassium, even from fruit, dangerous.

References

1. Bashir Y, Sneddon JF, Staunton A, et al. Effects of long-term oral magnesium chloride replacement in congestive heart failure secondary to coronary artery disease. Am J Cardiol 1993;72:1156-62.

2. Packer M, Gottlieb SS, Kessler PD. Hormone-electrolyte interactions in the pathogenesis of lethal cardiac arrhythmias in patients with congestive heart failure. Am J Med 1986;80 (Suppl 4A):23-9.

3. Chang HY, Hu YW, Yue CSJ, et al. Effect of potassium-enriched salt on cardiovascular mortality and medical expenses of elderly men. Am J Clin Nutr 2006;83:1289-96.

Stroke
Dose: Consult a qualified healthcare practitionerResearchers have found an association between diets low in potassium and increased risk of stroke.1, 2, 3 People who take potassium supplements have been reported to have a low risk of suffering a stroke.4 However, the association of increasing dietary potassium intake and decreasing stroke mortality only occurred in black men and hypertensive men in one study.5 Others have found an association between increased risk of stroke and the combination of low dietary potassium plus high salt intake.6 Increasing dietary potassium has lowered blood pressure in humans, which by itself should reduce the risk of stroke.7 However, some of the protective effect of potassium appears to extend beyond its ability to lower blood pressure.8 Maintaining a high potassium intake is best achieved by eating fruits and vegetables.
References

1. Ascherio A, Rimm EB, Hernan MA, et al. Intake of potassium, magnesium, calcium, and fiber and risk of stroke among US men. Circulation 1998;98:1198-204.

2. Sasaki S, Zhang XH, Kesteloot H. Dietary sodium, potassium, saturated fat, alcohol, and stroke mortality. Stroke 1995;26:783-9.

3. Khaw KT, Barrett-Connor E. Dietary potassium and stroke-associated mortality. A 12-year prospective population study. N Engl J Med 1987;316:235-40.

4. Ascherio A, Rimm EB, Hernan MA, et al. Intake of potassium, magnesium, calcium, and fiber and risk of stroke among US men. Circulation 1998;98:1198-204.

5. Fang J, Madhavan S, Alderman MH. Dietary Potassium Intake and Stroke Mortality. Stroke 2000;31:1532-7.

6. Yamori Y, Nara Y, Mizushima S, et al. Nutritional factors for stroke and major cardiovascular diseases: international epidemiological comparison of dietary prevention. Health Rep 1994;6:22-7.

7. Stamler J, Caggiula AW, Grandits GA. Relation of body mass and alcohol, nutrient, fiber, and caffeine intakes to blood pressure in the special intervention and usual care groups in the Multiple Risk Factor Intervention Trial. Am J Clin Nutr 1997;65:338S-65S.

8. Suter PM. The effects of potassium, magnesium, calcium, and fiber on risk of stroke. Nutr Rev 1999;57:84-8.

Cardiac Arrhythmia
Dose: 1,000 mg daily under medical supervision

Patients taking hydrochlorothiazide for high blood pressure had a significant reduction in arrhythmias when supplemented with 1 gram twice per day of potassium hydrochloride (supplying 1040 mg per day of elemental potassium). Those results were not improved by adding 500 mg twice per day of magnesium hydroxide (supplying 500 mg per day of elemental magnesium) to the potassium.1 Low serum concentrations of potassium were found to be associated with a higher incidence of arrhythmia in a large population study.2

References

1. Lumme JA, Jounela AJ. The effect of potassium and potassium plus magnesium supplementation on ventricular extrasystoles in mild hypertensives treated with hydrochlorothiazide. Int J Cardiol 1989;25:93-8.

2. Tsuji H, Venditti FJ, Evans JC, et al. The associations of levels of serum potassium and magnesium with ventricular premature complexes (the Framingham Heart Study). Am J Cardiol 1994;74:232-5.

Premenstrual Syndrome
Dose: 600 mg daily

A preliminary, uncontrolled trial found that women with severe PMS who took potassium supplements had complete resolution of PMS symptoms within four menstrual cycles.1 Most participants took 400 mg of potassium per day as potassium gluconate plus 200 mg of potassium per day as potassium chloride for the first two cycles, then switched to solely the gluconate form (600 mg potassium per day) for the remainder of the year-long trial. Without exception, all of the women found their symptoms (i.e., bloating, fatigue, irritability, etc.) decreasing gradually over three cycles and disappearing completely by the fourth cycle. Controlled trials are needed to confirm these preliminary observations.

References

1. Takacs BE. Potassium: A new treatment for premenstrual syndrome. J Orthomolec Med 1998;13:215-22.

Premenstrual Syndrome
Dose: 600 mg daily

A preliminary, uncontrolled trial found that women with severe PMS who took potassium supplements had complete resolution of PMS symptoms within four menstrual cycles.1 Most participants took 400 mg of potassium per day as potassium gluconate plus 200 mg of potassium per day as potassium chloride for the first two cycles, then switched to solely the gluconate form (600 mg potassium per day) for the remainder of the year-long trial. Without exception, all of the women found their symptoms (i.e., bloating, fatigue, irritability, etc.) decreasing gradually over three cycles and disappearing completely by the fourth cycle. Controlled trials are needed to confirm these preliminary observations.

References

1. Takacs BE. Potassium: A new treatment for premenstrual syndrome. J Orthomolec Med 1998;13:215-22.

Chronic Fatigue Syndrome
Dose: 1 gram of aspartates is taken twice per day

The combination of potassium aspartate and magnesium aspartate has shown benefits for chronically fatigued people in double-blind trials.1, 2, 3, 4 However, these trials were performed before the criteria for diagnosing CFS was established, so whether these people were suffering from CFS is unclear. Usually 1 gram of aspartates is taken twice per day, and results have been reported within one to two weeks.

References

1. Shaw DL, Chesney MA, Tullis IF, Agersborg HPK. Management of fatigue: a physiologic approach. Am J Med Sci 1962;243:758-69.

2. Crescente FJ. Treatment of fatigue in a surgical practice. J Abdom Surg 1962;4:73.

3. Hicks J. Treatment of fatigue in general practice: a double-blind study. Clin Med 1964;Jan:85-90.

4. Formica PE. The housewife syndrome: treatment with the potassium and magnesium salts of aspartic acid. Curr Ther Res 1962;Mar:98-106.

Potassium is an essential mineral needed to regulate water balance, levels of acidity, blood pressure, and neuromuscular function. This mineral also plays a critical role in the transmission of electrical impulses in the heart.

Copyright 2014 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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