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GNC alpha-Lipoic Acid 600 MG

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Description
Supports antioxidant regeneration & plays an important role in cell energy metabolism.*

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

As a dietary supplement, take on caplet daily. For maximum support, take a directed everyday.

Serving Size 1 Caplet
Servings Per Container 60
Amount Per Serving % DV
alpha-Lipoic Acid 600.00 mg **
** Daily Value (DV) not established

Other Ingredients: Cellulose, Dicalcium Phosphate, Natural Vanilla Flavor, Sucralose, Titanium Dioxide (Natural Mineral Whitener), Vegetable Acetaglycerides, Riboflavin

No Sugar, No Artificial Colors, No Artificials Flavors, No Preservatives, Sodium Free, No Wheat, No Gluten, No Soy, No Diary, Yeast Free

Distributed by: General Nutrition Corporation Pittsburgh, PA 15222

Health Notes

Alpha Lipoic Acid

Alpha Lipoic Acid
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Type 2 Diabetes
Dose: 600 to 1,200 mg a day
Taking alpha lipoic acid may improve insulin sensitivity and help protect against diabetic complications such as nerve damage.(more)
Type 1 Diabetes
Dose: 600 to 1,200 mg a day
Supplementing with alpha lipoic acid may protect against diabetic complications, such as nerve and kidney damage.(more)
Migraine Headache
Dose: 600 mg per day
In a small double-blind trial, supplementing with alpha-lipoic acid significantly reduced the frequency of migraine attacks.(more)
Obesity
Dose: Refer to label instructions
(more)
Glaucoma
Dose: Refer to label instructions
Alpha lipoic acid may improve visual function in people with some types of glaucoma.(more)
Vitiligo
Dose: Refer to label instructions
In one study, supplementing with a combination of antioxidants including alpha-lipoic acid increased the effectiveness of ultraviolet light therapy. (more)
Type 2 Diabetes
Dose: 600 to 1,200 mg a dayAlpha lipoic acid is a powerful natural antioxidant. Preliminary and double-blind trials have found that supplementing 600 to 1,200 mg of lipoic acid per day improves insulin sensitivity and the symptoms of diabetic neuropathy.1, 2, 3, 4, 5, 6, 7, 8 In a preliminary study, supplementing with 600 mg of alpha lipoic acid per day for 18 months slowed the progression of kidney damage in patients with type 2 diabetes.9
References

1. Konrad T, Vicini P, Kusterer K, et al. alpha lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes. Diabetes Care 1999;22:280-7.

2. Ruhnau KJ, Meissner HP, Finn JR, et al. Effects of 3-week oral treatment with the antioxidant thioctic acid (alpha-lipoic acid) in symptomatic diabetic polyneuropathy. Diabet Med 1999;16:1040-3.

3. Ruhnau KJ, Meissner HP, Finn JR, et al. Effects of 3-week oral treatment with the antioxidant thioctic acid (alpha-lipoic acid) in symptomatic diabetic polyneuropathy. Diabet Med 1999;16:1040-3.

4. Reljanovic M, Reichel G, Rett K, et al. Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): a two year multicenter randomized double-blind placebo-controlled trial (ALADIN II). Alpha Lipoic Acid in Diabetic Neuropathy. Free Radic Res 1999;31:171-9.

5. Ziegler D, Schatz H, Conrad F, et al. Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Diabetes Care 1997;20:369-73.

6. Jacob S, Ruus P, Hermann R, et al. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial. Free Radic Biol Med 1999;27:309-14.

7. Ziegler D, Hanefeld M, Ruhnau KJ, et al. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy. Diabetes Care 1999;22:1296-301.

8. Ziegler D, Ametov A, Barinov A, et al. Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diabetes Care 2006;29:2365-70.

9. Morcos M, Borcea V, Isermann B, et al. Effect of alpha-lipoic acid on the progression of endothelial cell damage and albuminuria in patients with diabetes mellitus: an exploratory study. Diabetes Res Clin Pract 2001;52:175-83.

Type 1 Diabetes
Dose: 600 to 1,200 mg a dayAlpha lipoic acid is a powerful natural antioxidant. Preliminary and double-blind trials have found that supplementing with 600 to 1,200 mg of lipoic acid per day improves the symptoms of diabetic nerve damage (neuropathy).1, 2, 3, 4 In a preliminary study, supplementing with 600 mg of alpha-lipoic acid per day for 18 months slowed the progression of kidney damage in people with type 1 diabetes.5
References

1. Ruhnau KJ, Meissner HP, Finn JR, et al. Effects of 3-week oral treatment with the antioxidant thioctic acid (alpha-lipoic acid) in symptomatic diabetic polyneuropathy. Diabet Med 1999;16:1040-3.

2. Ruhnau KJ, Meissner HP, Finn JR, et al. Effects of 3-week oral treatment with the antioxidant thioctic acid (alpha-lipoic acid) in symptomatic diabetic polyneuropathy. Diabet Med 1999;16:1040-3.

3. Reljanovic M, Reichel G, Rett K, et al. Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): a two year multicenter randomized double-blind placebo-controlled trial (ALADIN II). Alpha Lipoic Acid in Diabetic Neuropathy. Free Radic Res 1999;31:171-9.

4. Ziegler D, Hanefeld M, Ruhnau KJ, et al. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic Neuropathy. Diabetes Care 1999;22:1296-301.

5. Morcos M, Borcea V, Isermann B, et al. Effect of alpha-lipoic acid on the progression of endothelial cell damage and albuminuria in patients with diabetes mellitus: an exploratory study. Diabetes Res Clin Pract 2001;52:175-83.

Migraine Headache
Dose: 600 mg per day

In a small double-blind trial, supplementation with 600 mg of alpha-lipoic acid once a day for three months significantly reduced the frequency of migraine attacks. However, this improvement was not statistically significant when compared with the change in the placebo group.1 Additional research is needed to determine whether alpha-lipoic acid is effective for preventing migraines.

References

1. Magis D, Ambrosini A, Sandor P, et al. A randomized double-blind placebo-controlled trial of thioctic acid in migraine prophylaxis. Headache 2007;47:52-7.

Obesity
Dose: Refer to label instructionsIn a double-blind trial, obese people who supplemented with alpha-lipoic acid (1,200 or 1,800 mg per day for 20 weeks) resulted in a statistically significant weight loss, compared with a placebo. The amount of weight lost was 6.1 pounds with 1,800 mg per day of alpha-lipoic acid, 3.3 pounds with 1,200 mg per day, and 2.1 pounds with placebo.1 The weight loss was due primarily to a loss of fat mass, as opposed to muscle mass. It is not clear how alpha-lipoic acid works, but it may work by increasing the conversion of fuel to energy in the body.

References

1. Koh EH, Lee WJ, Lee SA, et al. Effects of alpha-lipoic acid on body weight in obese subjects. Am J Med 2011;124:85.e1-85.e8.

Glaucoma
Dose: Refer to label instructions

Alpha lipoic acid (150 mg per day for one month) improves visual function in people with some types of glaucoma.1

References

1. Filina AA, Davydova NG, Endrikhovskii SN, et al. Lipoic acid as a means of metabolic therapy of open-angle glaucoma. Vestn Oftalmol 1995;111:6-8.

Vitiligo
Dose: Refer to label instructionsIn a double-blind trial, supplementation with antioxidants for two months before and for six months during treatment with narrowband ultraviolet B light increased the effectiveness of the ultraviolet light therapy. The antioxidant supplement contained daily 100 mg of alpha-lipoic acid, 100 mg of vitamin C, 40 IU of vitamin E, and 100 mg of cysteine.1
References

1. Dell'Anna ML, Mastrofrancesco A, Sala R, et el. Antioxidants and narrow band-UVB in the treatment of vitiligo: a double-blind placebo controlled trial. Clin Exp Dermatol 2007;32:631-6.

Alpha lipoic acid (ALA) is a vitamin-like antioxidant, sometimes referred to as the "universal antioxidant" because it is soluble in both fat and water.1 ALA is manufactured in the body and is found in some foods, particularly liver and yeast.

Copyright 2014 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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Ratings and Reviews

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GNC alpha-Lipoic Acid 600 MG
 
5.0

(based on 2 reviews)

Reviewed by 2 customers

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(4 of 4 customers found this review helpful)

 
5.0

Alpha Lipoic Acid

By radtech37

from Indiana

About Me Medical Professional

See all my reviews

Pros

  • Easy on Stomach
  • Easy To Swallow
  • Effective
  • Simple To Take
  • Tastes Good
  • Vanilla Flavor

Cons

  • None

Best Uses

  • Daily Use
  • Men
  • Older People
  • Women

Comments about GNC alpha-Lipoic Acid 600 MG:

I have been taking ALA for over two years per my physicians recommendations. Liver enzymes have normalized for over a 1 1/2 now and neuropathy has improved. Very effective product !!!

(0 of 5 customers found this review helpful)

 
5.0

I buy this product all the time

By dnbmullinax

from Mt.Vernon,Il 62864

About Me Health Conscious

See all my reviews

Pros

  • Easy on Stomach
  • Easy To Swallow
  • Effective
  • Simple To Take

Cons

    Best Uses

    • Older People

    Comments about GNC alpha-Lipoic Acid 600 MG:

    I use Alpha Lipoic Acid for pain in my feet and it works well.

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