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Jarrow Formulas® MK-7
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Vitamin K2 as MK-7
Bone andCardiovascular Health*
Jarrow FORMULAS® MK-7 is an extract from genetically unmodified (non-GMO) soybeans fermented with Bacillus subtilus natto. MK-7 is concentrated without solvents. MK-7 (Menaquinone-7) is an enhanced bioactive form of vitamin K2, also known as Menaquinones. MK-7 from Natto is ten times better absorbed than K1 from spinach. MK-7 is responsible for the carboxylation of specific bone proteins needed for building bone.* Also, MK-7 promotes cardiovascular health by helping to maintain arterial elasticity.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
- Supplement Facts
USAGE: Take 1 softgel per day, or as directed by your qualified health care consultant.
Serving Size 1 softgels Servings Per Container 60 Amount Per Serving % DV MK-7 (vitamin K2 as menaquinone-7) 90.00 mcg ** ** Daily Value (DV) not established
Other Ingredients: Medium Chain Triglycerides, Evening Primrose Oil, Beeswax, Lecithin, Gelatin, Water, Glycerin, Caramel
No wheat, no gluten, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.
Warning: Consult your physician prior to using this product it you are pregnant, nursing, taking medication, under 18 years of age or have a medical condition. Discontinue use two weeks prior to surgery.KEEP OUT OF REACH OF CHILDREN.
WARNING: Do not use if taking anticoagulant drugs (such as Warfarin) or other medications.
Los Angeles, CA 90035-4317
- Health Notes
Vitamin KVitamin KThis nutrient has been used in connection with the following health goals
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
This supplement has been used in connection with the following health conditions:OsteoporosisDose: 1,000 mcg dailyVitamin K is needed for bone formation, and supplementing with it may be a way to maintain bone mass.(more)AtherosclerosisDose: 500 mcg per day of vitamin K1 In a double-blind trial, supplementing with vitamin K1 for three years appeared to slow the rate of progression of coronary artery calcification in seniors. (more)Celiac DiseaseDose: Consult a qualified healthcare practitionerThe malabsorption that occurs in celiac disease can lead to multiple nutritional deficiencies. Supplementing with vitamin K may correct a deficiency.(more)Crohn's DiseaseDose: 80 to 1,000 mcg dailyTaking vitamin K can counteract the deficiency and resulting bone loss that can occur in people with Crohn's disease.(more)Morning SicknessDose: Refer to label instructionsVitamin K and vitamin C, taken together, may provide relief of morning sickness symptoms for some women.(more)OsteoporosisDose: 1,000 mcg daily
Vitamin K is needed for bone formation. People with osteoporosis have been reported to have low blood levels1, 2 and low dietary intake of vitamin K.3, 4 One study found that postmenopausal (though not premenopausal) women may reduce urinary loss of calcium by taking 1 mg of vitamin K per day.5 People with osteoporosis given large amounts of vitamin K2 (45 mg per day) have shown an increase in bone density after six months6 and decreased bone loss after one7 or two8 years.
Other preliminary studies have reported that vitamin K supplementation increases bone formation in some women9 and that higher vitamin K intake correlates with greater bone mineral density.10 However, a double-blind study found that supplementing with 500 mcg of vitamin K1 per day for three years had no effect on bone mineral density, when compared with a placebo.11 Some doctors recommend 1 mg vitamin K1 to postmenopausal women as a way to help maintain bone mass, though optimal intake remains unknown.References
1. Hart JP. Circulating vitamin K1 levels in fractured neck of femur. Lancet 1984;2:283 [letter].
2. Tamatani M, Morimoto S, Nakajima M, et al. Decreased circulating levels of vitamin K and 25-hydroxyvitamin D in osteopenic elderly men. Metabolism 1998;47:195-9.
3. Feskanich D, Weber P, Willett WC, et al. Vitamin K intake and hip fractures in women: a prospective study. Am J Clin Nutr 1999;69:74-9.
4. Booth SL, Tucker KL, Chen H, et al. Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women. Am J Clin Nutr 2000;71:1201-8.
5. Knapen MHJ, Hamulyak K, Vermeer C. The effect of vitamin K supplementation on circulating osteocalcin (Bone Gla protein) and urinary calcium excretion. Ann Intern Med 1989;111:1001-5.
6. Orimo H, Shiraki M, Fujita T, et al. Clinical evaluation of Menatetrenone in the treatment of involutional osteoporosis-a double-blind multicenter comparative study with 1-alpha-hydroxyvitamin D3. J Bone Mineral Res 1992;7(Suppl 1):S122.
7. Iwamoto I, Kosha S, Noguchi S, et al. A longitudinal study of the effect of vitamin K2 on bone mineral density in postmenopausal women a comparative study with vitamin D3 and estrogen-progestin therapy. Maturitas 1999;31:161-4.
8. Shiraki M, Shiraki Y, Aoki C, Miura M. Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis. J Bone Miner Res 2000;15:515-21.
9. Craciun AM, Wolf J, Knapen MH, et al. Improved bone metabolism in female elite athletes after vitamin K supplementation. Int J Sports Med 1998;19:479-84.
10. Feskanich D, Weber P, Willett WC, et al. Vitamin K intake and hip fractures in women: a prospective study. Am J Clin Nutr 1999;69:74-9.
11. Booth SL, Dallal G, Shea MK, et al. Effect of vitamin K supplementation on bone loss in elderly men and women. J Clin Endocrinol Metab 2008;93:1217-23.AtherosclerosisDose: 500 mcg per day of vitamin K1 In a double-blind trial, supplementing with vitamin K1 for three years appeared to slow the rate of progression of coronary artery calcification in elderly people who had preexisting coronary artery calcification. Participants in that study were randomly assigned to receive a multivitamin that contained 500 mcg per day of vitamin K1 or the same multivitamin without vitamin K1.1ReferencesCeliac DiseaseDose: Consult a qualified healthcare practitioner
The malabsorption that occurs in celiac disease can lead to multiple nutritional deficiencies. The most common nutritional problems in people with celiac disease include deficiencies of essential fatty acids, iron, vitamin D, vitamin K, calcium, magnesium, and folic acid.1Zinc malabsorption also occurs frequently in celiac disease2 and may result in zinc deficiency, even in people who are otherwise in remission.3 People with newly diagnosed celiac disease should be assessed for nutritional deficiencies by a doctor. Celiac patients who have not yet completely recovered should supplement with a high-potency multivitamin-mineral. Some patients may require even higher amounts of some of these vitamins and minerals-an issue that should be discussed with their healthcare practitioner. Evidence of a nutrient deficiency in a celiac patient is a clear indication for supplementation with that nutrient.
After commencement of a gluten-free diet, overall nutritional status gradually improves. However, deficiencies of some nutrients may persist, even in people who are strictly avoiding gluten. For example, magnesium deficiency was found in 8 of 23 adults with celiac disease who had been following a gluten-free diet and were symptom-free. When these adults were supplemented with magnesium for two years, their bone mineral density increased significantly.4References
1. Connon JJ. Celiac disease. In: Shils ME, Olson JA, Shike M, eds. Modern Nutrition in Health and Disease, 8th ed. Philadelphia: Lea & Febiger, 1994, 1062.
2. Crofton RW, Glover SC, Ewen SWB, et al. Zinc absorption in celiac disease and dermatitis herpetiformis: a test of small intestinal function. Am J Clin Nutr 1983;38:706-12.
3. Solomons NW, Rosenberg IH, Sandstead HH. Zinc nutrition in celiac sprue. Am J Clin Nutr 1976;29:371-5.
4. Rude RK, Olerich M. Magnesium deficiency: possible role in osteoporosis associated with gluten-sensitive enteropathy. Osteoporos Int 1996;6:453-61.Crohn's DiseaseDose: 80 to 1,000 mcg daily
In people with Crohn's disease, vitamin K deficiency can result from malabsorption due to intestinal inflammation or bowel surgery, from chronic diarrhea, or from dietary changes necessitated by food intolerance. In addition, Crohn's disease is often treated with antibiotics that have the potential to kill beneficial vitamin K-producing bacteria in the intestines. Vitamin K levels were significantly lower in a group of people with Crohn's disease than in healthy people. Moreover, the rate of bone loss in the Crohn's disease patients increased with increasing degrees of vitamin K deficiency.1 When combined with earlier evidence that vitamin K is required to maintain healthy bones, this study suggests that vitamin K deficiency is a contributing factor to the accelerated bone loss that often occurs in people with Crohn's disease.ReferencesMorning SicknessDose: Refer to label instructions
Vitamin K and vitamin C, taken together, may provide relief of symptoms for some women. In one study, 91% of women who took 5 mg of vitamin K and 25 mg of vitamin C per day reported the complete disappearance of morning sickness within three days.1 Menadione was removed from the market a number of years ago because of concerns about potential toxicity. Although some doctors still use a combination of vitamin K1 (the most prevalent form of vitamin K in food) and vitamin C for morning sickness, no studies on this treatment have been done.References
Vitamin K is needed for proper bone formation and blood clotting. In both cases, vitamin K does this by helping the body transport calcium. Vitamin K is used by doctors when treating an overdose of the drug warfarin. Also, doctors prescribe vitamin K to prevent excessive bleeding in people taking warfarin but requiring surgery.
There is promising preliminary evidence that vitamin K2 (not vitamin K1), may improve a group of blood disorders known as myelodysplastic syndromes,1 which carry a significantly increased risk of progression to acute myeloid leukemia.
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.
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- Ratings and Reviews
Reviewed by 1 customer
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- Easy on Stomach
- Easy To Swallow
- Simple To Take
- Broken bones
Comments about Jarrow Formulas® MK-7:
I broke my foot and looked for supplements that would encourage bone growth to maybe speed up the process. I take 2 pills at a time in the morning with my vitamins, my foot feels great but i wont know if it helps until i get my x-rays taken again.
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