Jarrow Formulas® Red Yeast Rice + Nattokinase

Jarrow Formulas® Red Yeast Rice + Nattokinase - JARROW - GNC Zoom
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Item #230820

Size: 60 Veggie Caps

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Product Information

Description

Supports Cardiovascular Health*
Supports Healthy Circulation*
Jarrow Formulas® Red Yeast Rice + Nattokinase is designed to support cardiovascular health and circulation.* Jarrow Formulas® Nattokinase is made via fermentation by Bacillus subtillis natto and then purified. Red Yeast Rice is fermented by the yeast Monascus purpureus. Jarrow Formulas® uses Red Yeast Rice that is carefully fermented to avoid the presence of citrinin, a naturally-occurring mycotoxin. Each two capsules supply 2000 Fibrinolytic Units of activity from nattokinase to promote the breakdown (hydrolysis) of fibrin and - in conjunction with 1200 mg Red Yeast Race extract- support healthy circulation.*

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Supplement Facts

Serving Size 2 Capsules
Servings Per Container 30
Amount Per Serving % DV
Red Yeast Rice (Monascus purpureus) 1200.00 mg**
Natto Extract 100.00 mg**
Nattokinase 0.00 **
** Daily Value (DV) not established

Product Directions / Additional Info

Take 2 capsules per day with a meal or a glass of water or as directed by your qualified healthcare professional.

Other Ingredients: Maltodextrin, Cellulose, Magnesium Stearate (vegetable source), silicon dioxide, Capsule consists of hydroxypropylmethylcellulose

No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.

Warning: Keep out of reach of children

Do NOT use this product if you are pregnant, lactating or trying to conceive. NOTE: If you have a medical condition (especially bleeding disorders), are under the age of 18, or taking medications (especially either blood-thinning or blood-clotting medications), consult your healthcare professional before using this product.

Jarrow Formulas®
P.O. Box 35994
Los Angeles, CA 90035-4317

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Health Notes

Red Yeast Rice

Red Yeast Rice
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

High Cholesterol
Dose: 1.2 to 2.4 grams (5 to 10 mg of monacolins) daily in divided amounts
One of the ingredients in red yeast rice appears to block the production of cholesterol in the liver.(more)
High Triglycerides
Dose: 13.5 mg total monacolins daily
Although primarily used to lower high serum cholesterol, red yeast rice extract, high in monacolins, has been found to significantly lower serum triglyceride levels.(more)
Heart Attack
Dose: 300 mg twice a day (with doctor supervision)
In one trial that included patients with a previous history of a heart attack, supplementing with a particular brand of Chinese red yeast rice that contained 6 mg per day of lovastatin (a statin drug) reduced risk of death from heart disease. (more)
High Cholesterol
Dose: 1.2 to 2.4 grams (5 to 10 mg of monacolins) daily in divided amounts

Researchers have determined that one of the ingredients in red yeast rice, called monacolin K, inhibits the production of cholesterol by stopping the action of the key enzyme in the liver (HMG-CoA reductase) that is responsible for manufacturing cholesterol.1 Monacolin K is the same compound as lovastatin (Mevacor), a prescription drug used to treat high cholesterol. However, the amount of monacolin K in red yeast rice is small (5 mg per 2.4 grams of red yeast rice) when compared with the 20 to 40 mg of lovastatin typically used to lower cholesterol levels.2 It appears that monacolin compounds present in red yeast rice work together with monacolin K to produce a greater cholesterol-lowering effect than would be expected from the small amount of monacolin K alone.

The red yeast rice used in various studies was a proprietary product called Cholestin, which contains ten different monacolins.

Note: Cholestin has been banned in the United States, as a result of a lawsuit alleging patent infringement.

Other red yeast rice products currently on the market differ from Cholestin in their chemical makeup. None contain the full complement of ten monacolin compounds that are present in Cholestin, and some contain a potentially toxic fermentation product called citrinin.3 Despite these concerns, other red yeast rice products are being widely used and both anecdotal reports and clinical research suggest that they have a similar safety and efficacy profile as that of Cholestin.4, 5, 6

References

1. Endo A. Monacolin K, a new hypocholesterolemic agent produced by a Monascus species. J Antibiot (Tokyo) 1979;32:852-4.

2. Heber D, Yip I, Ashley JM, et al. Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement. Am J Clin Nutr 1999;69:231-6.

3. Heber D, Lembertas A, Lu QY, et al. An analysis of nine proprietary Chinese red yeast rice dietary supplements: implications of variability in chemical profile and contents. J Altern Complement Med 2001;7:133-9.

4. Huang CF, Li TC, Lin CC, et al. Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patients. Eur J Cardiovasc Prev Rehabil 2007;14:438-40.

5. Halbert SC, French B, Gordon RY, Farrar JT, Schmitz K, Morris PB, et al. Tolerability of red yeast rice (2,400 mg twice daily) versus pravastatin (20 mg twice daily) in patients with previous statin intolerance. Am J Cardiol 2010;105:198-204.

6. Venero CV, Venero JV, Wortham DC, Thompson PD. Lipid-lowering efficacy of red yeast rice in a population intolerant to statins. Am J Cardiol 2010;105:664-6.

High Triglycerides
Dose: 13.5 mg total monacolins daily

Although primarily used to lower high serum cholesterol, red yeast rice extract, high in monacolins, has been found to significantly lower serum triglyceride levels.1 People in the trial took 1.2 grams (approximately 13.5 mg total monacolins) of a concentrated red yeast rice extract per day for two months. The sale of Cholestin has been banned in the United States, as a result of a lawsuit alleging patent infringement. Other red yeast rice products currently on the market differ from Cholestin in their chemical makeup. None contain the full complement of 10 monacolin compounds that are present in Cholestin, and some contain a potentially toxic fermentation product called citrinin. 2 Until further information is available, red yeast rice products other than Cholestin cannot be recommended.

References

1. Wang J, Lu Z, Chi J, et al. Multicenter clinical trial of the serum lipid-lowering effects of a Monascus purpureus (red yeast) rice preparation from traditional Chinese medicine. Curr Ther Res 1997;58:964-77.

2. Heber D, Lembertas A, Lu QY, et al. An analysis of nine proprietary Chinese red yeast rice dietary supplements: implications of variability in chemical profile and contents. J Altern Complement Med 2001;7:133-9.

Heart Attack
Dose: 300 mg twice a day (with doctor supervision)In a double-blind trial that included patients with a previous history of a heart attack, supplementation with a particular brand of Chinese red yeast rice (Xuezhikang) in the amount of 300 mg twice a day for an average of 4.5 years reduced the death rate from heart disease by about one-third, compared with a placebo.1Xuezhikang is grown by a method that increases its content of lovastatin (a statin drug), and patients in this study received about 6 mg per day of lovastatin from taking Xuezhikang. It is not known whether other red yeast rice products would produce similar benefits.
References

1. Lu Z, Kou W, Du B, et al. Effect of Xuezhikang, an extract from red yeast Chinese rice, on coronary events in a Chinese population with previous myocardial infarction. Am J Cardiol 2008;101:1689-93.

Parts Used & Where Grown

This substance, native to China, is a fermentation by-product of cooked non-glutinous rice on which red yeast has been grown.1 The dried, powdered red yeast rice is used medicinally.

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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2017.