Now® Glucomannan

Now® Glucomannan - NOW NUTRITION - GNC Zoom
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Size: 180 Capsules

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Product Information

Description

575 mg - from Konjac Root
Healthy Weight Management*
  • Supports Healthy Cholesterol Levels already within healthy range*
  • Supports Regularity*
Glucomannan is a soluble, bulk-forming fiber derived from the konjac root (Amorphophallus konjac) that can help to maintain intestinal regularity.* Glucomannan may also help to maintain serum lipid levels already within the healthy range.* In addition, by promoting satiety (feeling of fullness), Glucomannan can be a convenient addition to a weight management plan that includes a healthy diet and exercise program.*

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Label

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Supplement Facts

Serving Size 3 Capsules
Servings Per Container 60
Amount Per Serving % DV
Calories 5.00
Total Carbohydrate 2.00 g1%
Dietary Fiber 2.00 g8%
Glucomannan (from Konjac Root)(Amorphophallus konjac) 1725.00 mg **
** Daily Value (DV) not established

Product Directions / Additional Info

Take 3 capsules 1 to 2 times daily with at least 8 oz. of water 30-45 minutes before a meal.

Other Ingredients: Gelatin (Capsule), Silica, Cellulose

Warning: For adults only. Take this product as recommended. Without drinking enough liquid the product may swell in the throat, causing blockage or choking. Avoid use if you ever had esophageal narrowing or swallowing difficulties. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.

NOW FOODS, 395 S. Glen Ellyn Rd.
Bloomingdale, IL 60108, USA

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Health Notes

Glucomannan

Glucomannan
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Insulin Resistance Syndrome
Dose: 8 to 13 grams daily
Taking a glucomannan fiber supplement may improve blood cholesterol and blood sugar.(more)
Type 2 Diabetes
Dose: 500 to 700 mg per 100 calories in the diet
Glucomannan delays stomach emptying, leading to more gradual sugar absorption and lower blood sugar levels after meals.(more)
Hypoglycemia
Dose: Refer to label instructions
Glucomannan is a water-soluble dietary fiber. In one trial, adding glucomannan to a meal prevented hypoglycemia in adults with previous stomach surgery.(more)
Type 1 Diabetes
Dose: Refer to label instructions
Glucomannan delays stomach emptying, leading to more gradual sugar absorption and possibly lowering insulin requirements for people with type 1 diabetes.(more)
High Cholesterol
Dose: 4 to 13 grams daily
Glucomannan is a water-soluble dietary fiber that has been shown to significantly reduce total blood cholesterol, LDL cholesterol, and triglycerides, and to raise HDL cholesterol.(more)
Constipation
Dose: 3 to 4 grams daily in water, followed by a second glass of water
Glucomannan is a water-soluble dietary fiber that has shown to be effective as a bulk-forming laxative.(more)
Diverticular Disease
Dose: Refer to label instructions
Glucomannan is a water-soluble dietary fiber. One study found that people with diverticular disease had reduced symptoms after taking glucommanan.(more)
Obesity
Dose: Adults: 3 to 4 grams daily; adolescents: 2 to 3 grams daily
Supplementing with glucomannan, a bulking agent, has promoted weight loss in overweight adults.(more)
Childhood Obesity
Dose: 2 to 3 grams daily
Glucomannan, a type of fiber, dilutes calories, slows down the eating process, and may make people feel more full despite eating fewer calories.(more)
Insulin Resistance Syndrome
Dose: 8 to 13 grams daily

Glucomannan, a type of water-soluble dietary fiber, may reduce many risk factors in people with IRS. A double-blind trial found that 8-13 grams per day of glucomannan significantly improved several measures of blood cholesterol control and one measure of blood glucose control in people with IRS.1 Another double-blind study of healthy people found that 30 grams per day of guar gum, a fiber similar to glucomannan, improved insulin sensitivity and many other components of IRS, including blood pressure and blood glucose, cholesterol, and triglycerides, leading the authors to recommend guar gum for people with IRS.2 However, in another study, obese people taking 8-16 grams per day of guar gum for 6-12 weeks did not experience any change in insulin sensitivity.3

References

1. Vuksan V, Sievenpiper JL, Owen R, et al. Beneficial effects of viscous dietary fiber from Konjac-mannan in subjects with the insulin resistance syndrome: results of a controlled metabolic trial. Diabetes Care 2000;23:9-14.

2. Landin K, Holm G, Tengborn L, Smith U. Guar gum improves insulin sensitivity, blood lipids, blood pressure, and fibrinolysis in healthy men. Am J Clin Nutr 1992;56:1061-5.

3. Cavallo-Perin P, Bruno A, Nuccio P, et al. Dietary guar gum supplementation does not modify insulin resistance in gross obesity. Acta Diabetol Lat 1985;22:139-142.

Type 2 Diabetes
Dose: 500 to 700 mg per 100 calories in the dietGlucomannan is a water-soluble dietary fiber derived from konjac root (Amorphophallus konjac)that delays stomach emptying, leading to a more gradual absorption of dietary sugar. This effect can reduce the elevation of blood sugar levels that is typical after a meal. 1 After-meal blood sugar levels are lower in people with diabetes given glucomannan in their food, 2 and overall diabetic control is improved with glucomannan-enriched diets, according to preliminary and controlled clinical trials. 3, 4, 5 One preliminary report suggested that glucomannan may also be helpful in pregnancy-related diabetes. 6 For controlling blood sugar, 500 to 700 mg of glucomannan per 100 calories in the diet has been used successfully in controlled research.
References

1. Doi K. Effect of konjac fibre (glucomannan) on glucose and lipids. Eur J Clin Nutr 1995;49(Suppl. 3):S190-7 [review].

2. Melga P, Giusto M, Ciuchi E, et al. Dietary fiber in the dietetic therapy of diabetes mellitus. Experimental data with purified glucomannans. Riv Eur Sci Med Farmacol 1992;14:367-73 [in Italian].

3. Huang CY, Zhang MY, Peng SS, et al. Effect of Konjac food on blood glucose level in patients with diabetes. Biomed Environ Sci 1990;3:123-31.

4. Vuksan V, Jenkins DJ, Spadafora P, et al. Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial. Diabetes Care 1999;22:913-9.

5. Vorster HH, Lotter AP, Odendaal I, et al. Benefits from supplementation of the current recommended diabetic diet with gel fibre. Int Clin Nutr Rev 1988;8:140-6.

6. Cesa F, Mariani S, Fava A, et al. The use of vegetable fibers in the treatment of pregnancy diabetes and/or excessive weight gain during pregnancy. Minerva Ginecol 1990;42:271-4 [in Italian].

Hypoglycemia
Dose: Refer to label instructions

Glucomannan is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). In a preliminary trial,1 addition of either 2.6 or 5.2 grams of glucomannan to a meal prevented hypoglycemia in adults with previous stomach surgery. A trial of glucomannan in children with hypoglycemia due to a condition known as "dumping syndrome" produced inconsistent results.2

References

1. Hopman WP, Houben PG, Speth PA, Lamers CB. Glucomannan prevents postprandial hypoglycaemia in patients with previous gastric surgery. Gut 1988;29:930-4.

2. Kneepkens CM, Fernandes J, Vonk RJ. Dumping syndrome in children. Diagnosis and effect of glucomannan on glucose tolerance and absorption. Acta Paediatr Scand 1988;77:279-86.

Type 1 Diabetes
Dose: Refer to label instructionsGlucomannan is a water-soluble dietary fiber derived from konjac root (Amorphophallus konjac). Glucomannan delays stomach emptying, leading to a more gradual absorption of dietary sugar. This effect can reduce the elevation of blood sugar levels that is typical after a meal.1 This could lower insulin requirements for type 1 diabetics, but no research has been done to test this possibility.
References

1. Doi K. Effect of konjac fibre (glucomannan) on glucose and lipids. Eur J Clin Nutr 1995;49(Suppl. 3):S190-7 [review].

High Cholesterol
Dose: 4 to 13 grams dailyGlucomannan is a water-soluble dietary fiber that is derived from konjac root. Controlled1, 2 and double-blind3, 4 trials have shown that supplementation with glucomannan significantly reduced total blood cholesterol, LDL cholesterol, and triglycerides, and in some cases raised HDL cholesterol. Effective amounts of glucomannan for lowering blood cholesterol have been 4 to 13 grams per day.
References

1. Vuksan V, Jenkins DJ, Spadafora P, et al. Konjac-mannan (glucomannan) improves glycemia and other associated risk factors for coronary heart disease in type 2 diabetes. A randomized controlled metabolic trial. Diabetes Care 1999;22:913-9.

2. Zhang MY, Huang CY, Wang X, et al. The effect of foods containing refined Konjac meal on human lipid metabolism. Biomed Environ Sci 1990;3:99-105.

3. Arvill A, Bodin L. Effect of short-term ingestion of konjac glucomannan on serum cholesterol in healthy men. Am J Clin Nutr 1995;61:585-9.

4. Walsh DE, Yaghoubian V, Behforooz A. Effect of glucomannan on obese patients: a clinical study. Int J Obes 1984;8:289-93.

Constipation
Dose: 3 to 4 grams daily in water, followed by a second glass of water

Glucomannan is a water-soluble dietary fiber that is derived from konjac root. Like other sources of fiber, such as psyllium and fenugreek, glucomannan is considered a bulk-forming laxative. A preliminary trial1 and several double-blind trials2, 3, 4, 5 have found glucomannan to be an effective treatment for constipation. The amount of glucomannan shown to be effective as a laxative is 3 to 4 grams per day. In constipated people, glucomannan and other bulk-forming laxatives generally help produce a bowel movement within 12 to 24 hours.

References

1. Passaretti S, Franzoni M, Comin U, et al. Action of glucomannans on complaints in patients affected with chronic constipation: a multicentric clinical evaluation. Ital J Gastroenterol 1991;23:421-5.

2. Marzio L, Del Bianco R, Donne M, et al. Mouth-to-cecum transit time in patients affected by chronic constipation: effect of glucomannan. Am J Gastroenterol 1989;84:888-91.

3. Marsicano LJ, Berrizbeitia ML, Mondelo A. Use of glucomannan dietary fiber in changes in intestinal habit. G E N 1995;49:7-14 [in Spanish].

4. Signorelli P, Croce P, Dede A. A clinical study of the use of a combination of glucomannan with lactulose in the constipation of pregnancy. Minerva Ginecol 1996;48:577-82 [in Italian].

5. Staianno A, Simeone D, Giudice ED, et al. Effect of the dietary fiber glucomannan on chronic constipation in neurologically impaired children. J Pediatr 2000;136:41-5.

Diverticular Disease
Dose: Refer to label instructions

Glucomannan is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). A preliminary clinical trial found that approximately one-third to one half of people with diverticular disease had reduced symptoms of diverticular disease after taking glucommanan.1 The amount of glucomannan shown to be effective as a laxative is 3-4 grams per day.

References

1. Papi C, Ciaco A, Koch M, Capurso L. Efficacy of rifaximin in the treatment of symptomatic diverticular disease of the colon. A multicentre double-blind placebo-controlled trial. Aliment Pharmacol Ther 1995;9:33-9.

Obesity
Dose: Adults: 3 to 4 grams daily; adolescents: 2 to 3 grams dailySupplementing with 3 to 4 grams per day of a bulking agent called glucomannan, with or without calorie restriction, has promoted weight loss in overweight adults,1, 2, 3 while 2 to 3 grams per day was effective in a group of obese adolescents in another controlled trial.4
References

1. Biancardi G, Palmiero L, Ghirardi PE. Glucomannan in the treatment of overweight patients with osteoarthritis. Curr Ther Res 1989;46:908-12.

2. Vita PM, Restelli A, Caspani P, Klinger R. Chronic use of glucomannan in the dietary treatment of severe obesity. Minerva Med 1992;83:135-9 [in Italian].

3. Walsh DE, Yaghoubian V, Behforooz A. Effect of glucomannan on obese patients: a clinical study. Int J Obes 1984;8:289-93.

4. Livieri C, Novazi F, Lorini R. The use of highly purified glucomannan-based fibers in childhood obesity. Pediatr Med Chir 1992;14:195-8 [in Italian].

Childhood Obesity
Dose: 2 to 3 grams daily

Increased fiber intake is thought to have potential benefit in a weight-loss program since dietary fiber dilutes calories, slows down the eating process, and may make people feel more full despite eating fewer calories.1 However, research on using fiber in the treatment of childhood obesity has focused on using fiber supplements rather than comparing low- and high-fiber diets. Supplementation for four months with 2 to 3 grams per day of a bulking agent called glucomannan, was effective in a group of obese adolescents in one controlled trial,2 but another controlled trial found no significant effect of 2 grams per day for two months.3

References

1. Kimm SY. The role of dietary fiber in the development and treatment of childhood obesity. Pediatrics 1995;96:1010-4.

2. Livieri C, Novazi F, Lorini R. The use of highly purified glucomannan-based fibers in childhood obesity. Pediatr Med Chir 1992;14:195-8 [in Italian].

3. Vido L, Facchin P, Antonello I, et al. Childhood obesity treatment: double blinded trial on dietary fibres (glucomannan) versus placebo. Padiatr Padol 1993;28:133-6.

Glucomannan is a water-soluble dietary fiber that is derived from konjac root (Amorphophallus konjac). Like other forms of dietary fiber, glucomannan is considered a "bulk-forming laxative." Glucomannan promotes a larger, bulkier stool that passes through the colon more easily and requires less pressure-and subsequently less straining-to expel.

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The information presented by Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2017.