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Now® Hyaluronic Acid

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Description


NOW® Hyaluronic Acid
Joint Support
Important Joint Jubricant
With MSM

Hyaluronic Acid is a compound present in every tissue of the body, with the highest concentrations occurring in connective tissues such as skin and cartilage. Hyaluronic Acid is an important constituent of joint fluid, where it serves as a lubricant and plays a role in resisting compressive forces. Look for other fine NOW products in health food stores nationwide.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

Suggested Usage: As a dietary supplement, take 2 Vcaps® 1-2 times daily, preferably with meals.

Serving Size 2 Vcaps
Servings Per Container 30
Amount Per Serving % DV
Sodium 9.00 mg 0%
Hyaluronic Acid 100.00 mg **
MSM (methylsulfonylmethane) 900.00 mg **
** Daily Value (DV) not established

Other Ingredients: Cellulose (capsule shell), Magnesium Stearate (Vegetable Source), silica

Contains no sugar, salt, starch, yeast, wheat, gluten, corn, milk, egg or preservatives.

Storage Instructions: STORE IN A COOL, DRY PLACE. CONTENTS SOLD BY WEIGHT NOT VOLUME.

Warning: Do Not Eat Freshness Packet. Keep in Bottle.

NOW FOODS, Bloomingdale, IL 60108

Health Notes

Hyaluronic Acid

Hyaluronic Acid
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Wound Healing
Dose: 1% solution for ears
Topically applied hyaluronic acid is sometimes used in skin wound dressings to improve healing.(more)
Skin Ulcers
Dose: Apply a gel containing a partial benzyl ester derivative of hyaluronan under compression bandaging daily
A trial found that topical application of a hyaluronic acid compound with compression bandaging was significantly better than bandaging alone for healing chronic venous skin ulcers.(more)
Wound Healing
Dose: 1% solution for ears
Topically applied hyaluronic acid is sometimes used in skin wound dressings to improve healing.(more)
Gingivitis
Dose: Apply five times per day for one week or twice per day for three weeks
Gels and sprays containing hyaluronic acid, an important connective tissue component in the gums, have been shown to help reduce bleeding tendency and other indicators of gingivitis.(more)
Osteoarthritis
Dose: Refer to label instructions
Injection of hyaluronic acid compounds into osteoarthritic joints, primarily the knee, has been shown to improve symptoms.(more)
Dry Eye Syndrome
Dose: Refer to label instructions
(more)
Wound Healing
Dose: 1% solution for ears

Topical application of hyaluronic acid and related compounds is sometimes used in skin wound dressings to improve healing.1 One controlled trial found a hyaluronic acid compound helpful for healing skin ulcers associated with chronic venous insufficiency.2 Improved healing of nasal surgery wounds with topical hyaluronic acid was reported in one controlled study,3 but not in another.4 A double-blind study found improved healing of perforated eardrums in patients using drops of 1% sodium hyaluronate.5 Whether oral hyaluronic acid supplements might improve wound healing has not been investigated.

References

1. Anderson I. The properties of hyaluronan and its role in wound healing. Prof Nurse 2001;17:232-5 [review].

2. Taddeucci P, Pianigiani E, Colletta V, et al. An evaluation of Hyalofill-F plus compression bandaging in the treatment of chronic venous ulcers. J Wound Care 2004;13:202-4.

3. Soldati D, Rahm F, Pasche P. Mucosal wound healing after nasal surgery. A controlled clinical trial on the efficacy of hyaluronic acid containing cream. Drugs Exp Clin Res 1999;25:253-61.

4. Miller RS, Steward DL, Tami TA, et al. The clinical effects of hyaluronic acid ester nasal dressing (Merogel) on intranasal wound healing after functional endoscopic sinus surgery. Otolaryngol Head Neck Surg 2003;128:862-9.

5. Rivas Lacarte MP, Casasin T, Pumarola F, Alonso A. An alternative treatment for the reduction of tympanic membrane perforations: sodium hyaluronate. A double blind study. Acta Otolaryngol 1990;110:110-4.

Skin Ulcers
Dose: Apply a gel containing a partial benzyl ester derivative of hyaluronan under compression bandaging daily

A controlled trial found that topical application of a hyaluronic acid compound with compression bandaging was significantly better than bandaging alone for healing chronic venous skin ulcers.1No research has investigated whether oral hyaluronic acid supplements might be similarly effective.

References

1. Taddeucci P, Pianigiani E, Colletta V, et al. An evaluation of Hyalofill-F plus compression bandaging in the treatment of chronic venous ulcers. J Wound Care 2004;13:202-4.

Wound Healing
Dose: 1% solution for ears

Topical application of hyaluronic acid and related compounds is sometimes used in skin wound dressings to improve healing.1 One controlled trial found a hyaluronic acid compound helpful for healing skin ulcers associated with chronic venous insufficiency.2 Improved healing of nasal surgery wounds with topical hyaluronic acid was reported in one controlled study,3 but not in another.4 A double-blind study found improved healing of perforated eardrums in patients using drops of 1% sodium hyaluronate.5 Whether oral hyaluronic acid supplements might improve wound healing has not been investigated.

References

1. Anderson I. The properties of hyaluronan and its role in wound healing. Prof Nurse 2001;17:232-5 [review].

2. Taddeucci P, Pianigiani E, Colletta V, et al. An evaluation of Hyalofill-F plus compression bandaging in the treatment of chronic venous ulcers. J Wound Care 2004;13:202-4.

3. Soldati D, Rahm F, Pasche P. Mucosal wound healing after nasal surgery. A controlled clinical trial on the efficacy of hyaluronic acid containing cream. Drugs Exp Clin Res 1999;25:253-61.

4. Miller RS, Steward DL, Tami TA, et al. The clinical effects of hyaluronic acid ester nasal dressing (Merogel) on intranasal wound healing after functional endoscopic sinus surgery. Otolaryngol Head Neck Surg 2003;128:862-9.

5. Rivas Lacarte MP, Casasin T, Pumarola F, Alonso A. An alternative treatment for the reduction of tympanic membrane perforations: sodium hyaluronate. A double blind study. Acta Otolaryngol 1990;110:110-4.

Gingivitis
Dose: Apply five times per day for one week or twice per day for three weeks

Hyaluronic acid is an important connective tissue component in the gums.1 Double-blind studies of topical hyaluronic acid treatments have shown that applying either a gel twice a day or a spray five times per day to the gum tissues helps reduce bleeding tendency and other indicators of gingivitis.2, 3 However, plaque removal is still necessary for best results, and one study found that adding weekly topical hyaluronic acid treatments to a single session of scaling and root planing did not make a significant difference in healing.4 No research has investigated whether hyaluronic acid supplements that are swallowed are effective for treating gingivitis.

References

1. Moseley R, Waddington RJ, Embery G. Hyaluronan and its potential role in periodontal healing. Dent Update 2002;29:144-8 [review].

2. Pistorius A, Martin M, Willershausen B, Rockmann P. The clinical application of hyaluronic acid in gingivitis therapy. Quintessence Int 2005;36:531-8.

3. Jentsch H, Pomowski R, Kundt G, Gocke R. Treatment of gingivitis with hyaluronan. J Clin Periodontol 2003;30:159-64.

4. Xu Y, Hofling K, Fimmers R, et al. Clinical and microbiological effects of topical subgingival application of hyaluronic acid gel adjunctive to scaling and root planing in the treatment of chronic periodontitis. J Periodontol 2004;75:1114-8.

Osteoarthritis
Dose: Refer to label instructions

Hyaluronic acid is a normal component of joint fluid, but its amount and molecular structure are altered in osteoarthritic joints.1 Injection of hyaluronic acid compounds into osteoarthritic joints, primarily the knee, has been investigated in many double-blind trials with some improvement demonstrated.2, 3, 4 However, no research has been done to determine whether oral supplementation with hyaluronic acid is an effective treatment for osteoarthritis.

References

1. Tehranzadeh J, Booya F, Root J. Cartilage metabolism in osteoarthritis and the influence of viscosupplementation and steroid: a review. Acta Radiol2005;46:288-96 [review].

2. Modawal A, Ferrer M, Choi HK, Castle JA. Hyaluronic acid injections relieve knee pain. J Fam Pract 2005;54:758-67 [review].

3. Bellamy N, Campbell J, Robinson V, et al . Viscosupplementation for the treatment of osteoarthritis of the knee. Cochrane Database Syst Rev 2005;(2):CD005321 [review].

4. Arrich J, Piribauer F, Mad P, et al. Intra-articular hyaluronic acid for the treatment of osteoarthritis of the knee: systematic review and meta-analysis. CMAJ 2005;172:1039-43 [review].

Dry Eye Syndrome
Dose: Refer to label instructionsIn a double-blind trial, application of eye drops containing 0.18% sodium hyaluronate (the sodium salt of hyaluronic acid) improved symptoms and objective signs in people with dry eye syndrome. The amount used was 1 or 2 drops in each eye 3 to 6 times per day for 14 days.1 Several other trials have confirmed the effectiveness of sodium hyaluronate eye drops for dry eye syndrome.
References

1. Vogel R, Crockett RS, Oden N, et al. Demonstration of efficacy in the treatment of dry eye disease with 0.18% sodium hyaluronate ophthalmic solution (Vismed, Rejena). Am J Ophthalmol 2010;149:594-601.

Hyaluronic acid is a member of the family of molecules known as glycosaminoglycans. This family also includes chondroitin sulfate and some other large carbohydrate-containing molecules. Hyaluronic acid is an important component of the connective tissue that fills the spaces between cells of the skin and other tissues, and is a major ingredient of the synovial fluid that lubricates and cushions joints as well as the vitreous humor that fills the inner chamber of the eye.1

Copyright 2014 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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Ratings and Reviews

REVIEW SNAPSHOT®

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NOW NUTRITIONNow® Hyaluronic Acid
 
4.3

(based on 4 reviews)

75%

of respondents would recommend this to a friend.

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      Reviewed by 4 customers

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      5.0

      excellent product

      By steinmeg

      from lake wroth fl

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            Comments about NOW NUTRITION Now® Hyaluronic Acid:

            none

            • My Beauty Routine Takes:
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            3.0

            Hyaluronic Acid may be helping me?

            By frwinkler

            from Montgomery. Alabama

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            Pros

            • Easy To Use

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              • Daily Use

              Comments about NOW NUTRITION Now® Hyaluronic Acid:

              I suffer from preliminary stages of osteopenosis and osteoperosis in my hip joints and lower back. Have been taking this product for a few years, (in addition to calcium- Dr's suggestion- and a variety of other vitamins & supplements)and can't honestly say that it has made any difference. My brother (a professional skydiver with over 10,000 jumps) swears by this product, which he says has helped him regarding joint issues he experiences.

               
              5.0

              I would buy this product again

              By Lisaw

              from Philadelphia PA

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              Pros

              • Easy to take with food
              • Easy To Use
              • Effective
              • Effective in health care
              • Good Value
              • Lightweight

              Cons

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                • Daily Use
                • On-the-go
                • Use for high performance
                • Women

                Comments about NOW NUTRITION Now® Hyaluronic Acid:

                use for athletic performance -keeps body going strong

                • My Beauty Routine Takes:
                • 10 Minutes

                (11 of 11 customers found this review helpful)

                 
                4.0

                joint ache easer

                By catercynthia255

                from nyc

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                Pros

                • Easy to take swallow
                • Effective

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                  Comments about NOW NUTRITION Now® Hyaluronic Acid:

                  I recently start taking this supplement and i notice that the pain in my knees is not as severe. I did not have to take any pain medications to relieve the pain.

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