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Now® Pyruvate 1000 mg

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Description
Extra Strength Calcium Pyruvate

NOW® Calcium Pyruvate is a natural combination of two important nutrients - Calcium and Pyruvic Acid. This combination produces a stable compound called pyruvate salt that is more easily absorbed than calcium alone. Calcium Pyruvate also plays a crucial role in energy production by facilitating the transport of glucose from the bloodstream into the muscles, making this a popular supplement with fitness enthusiasts and body builders.*

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

As a dietary supplement, take 2 tablets 1-3 times daily, preferably with meals. We recommend using this product with a rigorous diet and exercise program for best results.

Serving Size 2 Tablets
Servings Per Container 45
Amount Per Serving % DV
Calcium 320.00 mg 30%
Calcium Pyruvate 2000.00 mg **
** Daily Value (DV) not established

Other Ingredients: Cellulose, Magensium Stearate (Vegetable Source)

No Sugar, No Salt, No Starch, No Yeast, No Wheat, No Gluten, No Corn, No Soy, No Milk, No Egg, No Preservatives

Warning: Consult your physician prior to using this product it you are pregnant, nursing, taking medication, under 18 years of age or have a medical condition. Discontinue use two weeks prior to surgery.KEEP OUT OF REACH OF CHILDREN.

Caution: Please discard the inedible freshness packet enclosed.

Manufactured by NOW FOODS
BLOOMINGDALE, IL 60108
NOW® Calcium Pyruvate contains 65-70% Pyruvic Acid. Calcium Pyruvate is a fully reacted supplement that combines Pyruvic Acid with Calcium.

Health Notes

Pyruvate

Pyruvate
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Obesity
Dose: 6 to 10 grams daily combined with an exercise program
Combining exercise with pyruvate may help speed up your metabolism.(more)
Athletic Performance
Dose: 100 grams of a combination of dihydroxyacetone and pyruvate
One group of researchers has reported that a combination of dihydroxyacetone and pyruvate enhanced the endurance of certain muscles. (more)
Athletic Performance and Improving Body Composition with Strength Training in Untrained People
Dose: Refer to label instructions
Three controlled studies of people using a combination of pyruvate and an exercise program reported positive effects on weight loss and body fat. (more)
Obesity
Dose: 6 to 10 grams daily combined with an exercise programPyruvate, a compound that occurs naturally in the body, might aid weight-loss efforts.1 A controlled trial found that pyruvate supplements (22 to 44 grams per day) enhanced weight loss and resulted in a greater reduction of body fat in overweight adults consuming a low-fat diet.2 Three controlled trials combining 6 to 10 grams per day of pyruvate with an exercise program reported greater effects on weight loss and body fat than that seen with a placebo plus the exercise program.3, 4, 5 Animal studies suggest that pyruvate supplementation leads to weight loss by increasing the resting metabolic rate.6
References

1. Stanko RT, Tietze DL, Arch JE. Body composition, energy utilization, and nitrogen metabolism with a 4.25-MJ/d low-energy diet supplemented with pyruvate. Am J Clin Nutr 1992;56:630-5.

2. Stanko RT, Reynolds HR, Hoyson R, et al. Pyruvate supplementation of a low-cholesterol, low-fat diet: Effects on plasma lipid concentration and body composition in hyperlipidemic patients. Am J Clin Nutr 1994;59:423-7.

3. Kalman D, Colker CM, Wilets I, et al. The effects of pyruvate supplementation on body composition in overweight individuals. Nutrition 1999;15:337-40.

4. Kalman D, Colker CM, Stark S, et al. Effect of pyruvate supplementation on body composition and mood. Curr Ther Res 1998;59:793-802.

5. Kreider R, Koh P, Ferreira M, et al. Effects of pyruvate supplementation during training on body composition & metabolic responses to exercise. Med Sci Sports Exerc 1998;30:S62 [abstract].

6. Ivy JL, Cortez MY, Chandler RM, et al. Effects of pyruvate on the metabolism and insulin resistance of obese Zucker rats. Am J Clin Nutr 1994;59:331-7.

Athletic Performance
Dose: 100 grams of a combination of dihydroxyacetone and pyruvate

One group of researchers in two small, controlled trials has reported that 100 grams of a combination of dihydroxyacetone and pyruvate enhanced the endurance of certain muscles in untrained men.1, 2 Three controlled studies of untrained individuals using a combination of 6 to 10 grams per day of pyruvate and an exercise program reported greater effects on weight loss and body fat compared with those taking a placebo with the exercise program.3, 4, 5 However, in a study of healthy untrained women undergoing an exercise program, supplementing with 5 grams of pyruvate twice a day had no effect on exercise performance.6 Studies of pyruvate supplementation on exercise performance in trained athletes have also failed to demonstrate any beneficial effect. Seven grams per day did not improve aerobic exercise performance in cyclists,7 and an average of 15 grams per day did not improve anaerobic performance or body composition in football players.8 More recently, evidence has appeared casting doubt on the ability of high levels (an average exceeding 15 grams per day depending upon body weight) of pyruvate to improve exercise capacity in a weight-lifting study.9

References

1. Stanko RT, Robertson RJ, Galbreath RW, et al. Enhanced leg exercise endurance with a high-carbohydrate diet and dihyroxyacetone and pyruvate. J Appl Phys 1990;69:1651-6.

2. Stanko RT, Robertson RJ, Spina RJ, et al. Enhancement of arm exercise endurance capacity with dihydroxyacetone and pyruvate. J Appl Phys 1990;68:119-24.

3. Kalman D, Colker CM, Wilets I, et al. The effects of pyruvate supplementation on body composition in overweight individuals. Nutrition 1999;15:337-40.

4. Kreider R, Koh P, Ferreira M, et al. Effects of pyruvate supplementation during training on body composition & metabolic responses to exercise. Med Sci Sports Exerc 1998;30:S62 [abstract].

5. Kalman D, Colker CM, Stark S, et al. Effect of pyruvate supplementation on body composition and mood. Curr Ther Res 1998;59:793-802.

6. Koh-Banerjee PK, Ferreira MP, Greenwood M, et al. Effects of calcium pyruvate supplementation during training on body composition, exercise capacity, and metabolic responses to exercise. Nutr 2005;21:312-9.

7. Morrison MA, Spriet LL, Dyck DJ. Pyruvate ingestion for 7 days does not improve aerobic performance in well-trained individuals. J Appl Physiol 2000;89:549-56.

8. Stone MH, Sanborn K, Smith LL, et al. Effects of in-season (5 weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Int J Sport Nutr 1999;9:146-65.

9. Stone MH, Sanborn K, Smith LL, et al. Effects of in-season (5 weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Int J Sport Nutr 1999;9:146-65.

Athletic Performance and Improving Body Composition with Strength Training in Untrained People
Dose: Refer to label instructions

One group of researchers in two small, controlled trials has reported that 100 grams of a combination of dihydroxyacetone and pyruvate enhanced the endurance of certain muscles in untrained men.1, 2 Three controlled studies of untrained individuals using a combination of 6 to 10 grams per day of pyruvate and an exercise program reported greater effects on weight loss and body fat compared with those taking a placebo with the exercise program.3, 4, 5 However, in a study of healthy untrained women undergoing an exercise program, supplementing with 5 grams of pyruvate twice a day had no effect on exercise performance.6 Studies of pyruvate supplementation on exercise performance in trained athletes have also failed to demonstrate any beneficial effect. Seven grams per day did not improve aerobic exercise performance in cyclists,7 and an average of 15 grams per day did not improve anaerobic performance or body composition in football players.8 More recently, evidence has appeared casting doubt on the ability of high levels (an average exceeding 15 grams per day depending upon body weight) of pyruvate to improve exercise capacity in a weight-lifting study.9

References

1. Stanko RT, Robertson RJ, Galbreath RW, et al. Enhanced leg exercise endurance with a high-carbohydrate diet and dihyroxyacetone and pyruvate. J Appl Phys 1990;69:1651-6.

2. Stanko RT, Robertson RJ, Spina RJ, et al. Enhancement of arm exercise endurance capacity with dihydroxyacetone and pyruvate. J Appl Phys 1990;68:119-24.

3. Kalman D, Colker CM, Wilets I, et al. The effects of pyruvate supplementation on body composition in overweight individuals. Nutrition 1999;15:337-40.

4. Kreider R, Koh P, Ferreira M, et al. Effects of pyruvate supplementation during training on body composition & metabolic responses to exercise. Med Sci Sports Exerc 1998;30:S62 [abstract].

5. Kalman D, Colker CM, Stark S, et al. Effect of pyruvate supplementation on body composition and mood. Curr Ther Res 1998;59:793-802.

6. Koh-Banerjee PK, Ferreira MP, Greenwood M, et al. Effects of calcium pyruvate supplementation during training on body composition, exercise capacity, and metabolic responses to exercise. Nutr 2005;21:312-9.

7. Morrison MA, Spriet LL, Dyck DJ. Pyruvate ingestion for 7 days does not improve aerobic performance in well-trained individuals. J Appl Physiol 2000;89:549-56.

8. Stone MH, Sanborn K, Smith LL, et al. Effects of in-season (5 weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Int J Sport Nutr 1999;9:146-65.

9. Stone MH, Sanborn K, Smith LL, et al. Effects of in-season (5 weeks) creatine and pyruvate supplementation on anaerobic performance and body composition in American football players. Int J Sport Nutr 1999;9:146-65.

Pyruvate (the buffered form of pyruvic acid) is a product created in the body during the metabolism of carbohydrates and protein.

Copyright 2014 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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      5.0

      I love it!

      By marciarams

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        Comments about NOW NUTRITION Now® Pyruvate 1000 mg:

        Dr. Oz mentioned Pyruvate Calcium.

        (2 of 5 customers found this review helpful)

         
        4.0

        Prompt delivery. Will order again.

        By amurphything

        from Griffin, GA

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          Comments about NOW NUTRITION Now® Pyruvate 1000 mg:

          I was advised to use this product by a doctor when I was on a weight loss program and have continued to use it for several years.

          (1 of 2 customers found this review helpful)

           
          4.0

          Great product

          By jeff5328

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