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Source Naturals® Vinpocetine

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60 Tablets

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Description
Vinpocetine is a derivative of vincamine, a key component of the lesser periwinkle plant. Research suggests vinpocetine may improve cognitive performance and short-term memory loss that is sometimes experienced with stress or aging. Animal studies have shown that vinpocetine significantly increases circulatory parameters including total cerebral blood flow.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

1 tablet 1 to 3 times daily with food. Do not exceed three tablets per day.

Serving Size 1 Tablet
Servings Per Container 60
Amount Per Serving % DV
Vinpocetine 10.00 mg **
** Daily Value (DV) not established

Other Ingredients: Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate

Contains no yeast, dairy, egg, gluten, corn, soy, wheat, sugar, starch, salt, preservatives, and artificial color, flavor and fragrance.

Warning: Do not use if either tamper evident seal is broken or missing.
Keep out of reach of children.

May cause stomach upset if taken on an empty stomach. If you have low blood pressure, have a history of heart problems, strokes or are using blood-thinning medications, consult your doctor before using this product. For adult use only. Not for use by pregnant, may become pregnant, or breastfeeding women.

Source Naturals Inc. P.O. Box 2118 Santa Cruz, CA 95062

Health Notes

Vinpocetine

Vinpocetine
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Stroke
Dose: 30 to 60 mg per day taken with food
Vinpocetine injections have been reported to improve some measures of brain function in stroke patients and to reduce some of the brain function loss that typically follows a stroke.(more)
Urinary Incontinence
Dose: 5 mg three times daily for two weeks, then 10 mg three times daily for two weeks
In a small, preliminary study, some men and women with urge incontinence reported reduced symptoms and also improved in laboratory measures of bladder muscle control when supplementing with vinpocetine. (more)
Age-Related Cognitive Decline
Dose: 30 to 60 mg daily
Vinpocetine has been shown to improve dementia symptoms in patients with various brain diseases.(more)
Memory
Dose: Refer to label instructions
(more)
Age-Related Cognitive Decline
Dose: 30 to 60 mg daily
Vinpocetine has been shown to improve dementia symptoms in patients with various brain diseases.(more)
Vertigo
Dose: 15 mg daily
Supplementing with vinpocetine has been shown to ease symptoms.(more)
Retinopathy
Dose: Refer to label instructions
Preliminary studies have reported improved vision in people with various diseases of the retina who took vinpocetine.(more)
Retinopathy
Dose: Refer to label instructions
Preliminary studies have reported improved vision in people with various diseases of the retina who took vinpocetine.(more)
Stroke
Dose: 30 to 60 mg per day taken with food

Vinpocetine given by intravenous injection has been reported to improve some biochemical measures of brain function in stroke patients.1, 2 A controlled trial found intravenous vinpocetine given within 72 hours of a stroke reduced some of the losses in brain function that typically follow a stroke.3 However, the reliability of human stroke research using vinpocetine has been questioned,4, 5 and more double-blind trials are needed. No studies using oral vinpocetine for treating acute strokes have been published.

References

1. Gulyas B, Bonoczk P, Vas A, et al. [The effect of a single-dose intravenous vinpocetine on brain metabolism in patients with ischemic stroke.] Orv Hetil2001;142:443-9 [in Hungarian].

2. Szakall S, Boros I, Balkay L, et al. Cerebral effects of a single dose of intravenous vinpocetine in chronic stroke patients: a PET study. J Neuroimaging1998;8:197-204.

3. Feigin VL, Doronin BM, Popova TF, et al. Vinpocetine treatment in acute ischaemic stroke: a pilot single-blind randomized clinical trial. Eur J Neurol2001;8:81-5.

4. Bereczki D, Fekete I. A systematic review of vinpocetine therapy in acute ischaemic stroke. Eur J Clin Pharmacol 1999;55:349-52 [review].

5. Bereczki D, Fekete I. Vinpocetine for acute ischaemic stroke. Cochrane Database Sys Rev2000;2:CD000480.

Urinary Incontinence
Dose: 5 mg three times daily for two weeks, then 10 mg three times daily for two weeks Vinpocetine is a semisynthetic derivative of vincamine, one of the major active compounds found in periwinkle. In a small, preliminary study, men and women with urge incontinence were given 5 mg of vinpocetine three times daily for two weeks, then 10 mg three times daily for an additional two weeks. About half of the subjects reported reduced symptoms of urge incontinence and also improved in laboratory measures of bladder muscle control.1 However, a small, double-blind trial found improvement in only one of several measures of urge incontinence.2 More double blind trials are needed to confirm these findings.
References

1. Truss MC, Stief CG, Uckert S, et al. Initial clinical experience with the selective phosphodiesterase-I isoenzyme inhibitor vinpocetine in the treatment of urge incontinence and low compliance bladder. World J Urol 2000;18:439-43.

2. Truss MC, Stief CG, Uckert S, et al. Phosphodiesterase 1 inhibition in the treatment of lower urinary tract dysfunction: from bench to bedside. World J Urol 2001;19:344-50 [review].

Age-Related Cognitive Decline
Dose: 30 to 60 mg daily

A double-blind trial found both 30 mg and 60 mg per day of vinpocetine improved symptoms of dementia in patients with various brain diseases.1 Another double-blind trial gave 30 mg per day of vinpocetine for one month, followed by 15 mg per day for an additional two months, to people with dementia associated with hardening of the arteries of the brain, and significant improvement in several measures of memory and other cognitive functions was reported.2 Other double-blind trials have reported similar effects of vinpocetine in people with some types of dementia or age-related cognitive decline.3, 4 However, a study of Alzheimer patients in the United States found vinpocetine given in increasing amounts from 30 mg to 60 mg per day over the course of a year neither reversed nor slowed the decline in brain function measured by a number of different tests.5

References

1. Hindmarch I, Fuchs HH, Erzigkeit H. Efficacy and tolerance of vinpocetine in ambulant patients suffering from mild to moderate organic psychosyndromes. Int Clin Psychopharmacol 1991;6:31-43.

2. Balestreri R, Fontana L, Astengo F. A double-blind placebo controlled evaluation of the safety and efficacy of vinpocetine in the treatment of patients with chronic vascular senile cerebral dysfunction. J Am Geriatr Soc 1987;35:425-30.

3. Peruzza M, DeJacobis M. A double-blind placebo controlled evaluation of the efficacy and safety of vinpocetine in the treatment of patients with chronic vascular or degenerative senile cerebral dysfunction. Adv Ther 1986;3:201-9.

4. Manconi E, Binaghi F, Pitzus F. A double-blind clinical trial of vinpocetine in the treatment of cerebral insufficiency of vascular and degenerative origin. Curr Ther Res Clin Exp1986;30:702-709.

5. Thal LJ, Salmon DP, Lasker B, et al. The safety and lack of efficacy of vinpocetine in Alzheimer's disease. J Am Geriatr Soc 1989;37:515-20.

Memory
Dose: Refer to label instructions
Age-Related Cognitive Decline
Dose: 30 to 60 mg daily

A double-blind trial found both 30 mg and 60 mg per day of vinpocetine improved symptoms of dementia in patients with various brain diseases.1 Another double-blind trial gave 30 mg per day of vinpocetine for one month, followed by 15 mg per day for an additional two months, to people with dementia associated with hardening of the arteries of the brain, and significant improvement in several measures of memory and other cognitive functions was reported.2 Other double-blind trials have reported similar effects of vinpocetine in people with some types of dementia or age-related cognitive decline.3, 4 However, a study of Alzheimer patients in the United States found vinpocetine given in increasing amounts from 30 mg to 60 mg per day over the course of a year neither reversed nor slowed the decline in brain function measured by a number of different tests.5

References

1. Hindmarch I, Fuchs HH, Erzigkeit H. Efficacy and tolerance of vinpocetine in ambulant patients suffering from mild to moderate organic psychosyndromes. Int Clin Psychopharmacol 1991;6:31-43.

2. Balestreri R, Fontana L, Astengo F. A double-blind placebo controlled evaluation of the safety and efficacy of vinpocetine in the treatment of patients with chronic vascular senile cerebral dysfunction. J Am Geriatr Soc 1987;35:425-30.

3. Peruzza M, DeJacobis M. A double-blind placebo controlled evaluation of the efficacy and safety of vinpocetine in the treatment of patients with chronic vascular or degenerative senile cerebral dysfunction. Adv Ther 1986;3:201-9.

4. Manconi E, Binaghi F, Pitzus F. A double-blind clinical trial of vinpocetine in the treatment of cerebral insufficiency of vascular and degenerative origin. Curr Ther Res Clin Exp1986;30:702-709.

5. Thal LJ, Salmon DP, Lasker B, et al. The safety and lack of efficacy of vinpocetine in Alzheimer's disease. J Am Geriatr Soc 1989;37:515-20.

Vertigo
Dose: 15 mg daily

A preliminary trial showed that 15 mg per day of vinpocetine had a moderate or greater effect on reducing the signs and symptoms of vertigo in 77% of patients with this condition.1 Other preliminary reports exist describing benefits of vinpocetine for vertigo and other symptoms of inner ear disorders,2 but controlled research is needed to evaluate these claims.

References

1. Taiji H, Kanzaki J. Clinical study of vinpocetine in the treatment of vertigo. Jpn Pharmacol and Ther (Japan) 1986;14:577-89.

2. Ribari O, Zelen B, Kollar B. Ethyl apovincaminate in the treatment of sensorineural impairment of hearing. Arzneimittelforschung 1976;26:1977-80.

Retinopathy
Dose: Refer to label instructions

Preliminary studies have reported improved vision in people with various diseases of the retina who took 45 mg per day of vinpocetine.1

References

1. Brooser G, Anda L, Doman J. Preliminary report on the use of ethyl apovincaminate in affections of the eyeground. Arzneimittelforschung 1976;26:1973-5.

Retinopathy
Dose: Refer to label instructions

Preliminary studies have reported improved vision in people with various diseases of the retina who took 45 mg per day of vinpocetine.1

References

1. Brooser G, Anda L, Doman J. Preliminary report on the use of ethyl apovincaminate in affections of the eyeground. Arzneimittelforschung 1976;26:1973-5.

Vinpocetine is a chemical substance synthesized from vincamine, a natural constituent found in the leaves of Vinca minor (lesser periwinkle).

Copyright 2014 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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Ratings and Reviews

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Source Naturals® Vinpocetine
 
4.5

(based on 2 reviews)

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(1 of 3 customers found this review helpful)

 
4.0

Beneficial

By jnheatherly

from Knoxville, TN

About Me First Time User

See all my reviews

Pros

  • Good Value
  • Natural-Feeling Results
  • No Side Effects

Cons

    Best Uses

    • Afternoon
    • Morning

    Comments about Source Naturals® Vinpocetine:

    I take it morning and evening. After 5-7 days of use, I found it very beneficial and will continue to use it.

    (3 of 5 customers found this review helpful)

     
    5.0

    An essential every day, it works

    By TEAMBAUCH

    from Trabuco Canyon, CA

    About Me Health Conscious, Regular User

    See all my reviews

    Verified Buyer

    Pros

    • Good Value
    • Natural-Feeling Results
    • No Side Effects

    Cons

      Best Uses

      • Morning

      Comments about Source Naturals® Vinpocetine:

      Has definitely sharpened my brain.

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