Instaflex® Advanced | GNC

Instaflex® Advanced


Item # 452399


Free Shipping on Orders of $49 or More! Details
Free Shipping on Orders of $49 or More!
Size: 30 Capsules

Add to cart options

Product Options

Product Actions


Product Information


Featuring UC-II® Collagen
Doctor Formulated
  • Relieve Discomfort*
  • Improve Flexibility*
  • Joint Relief in 7 Days*
One Small Capsule Daily

Regain Mobility with Instaflex Advanced Just one small capsule once a day can lead to more comfortable joints in as little as 7 days. CLINICAL STUDIES SHOW:
  • Aprèsflex® improves joint stiffness and discomfort by more than 60% when compared to placebo after 90 days.*
  • UC-II® Collagen significantly reduces knee discomfort and is twice as effective as glucosamine plus chondroitin.*
  • BioPerine® significantly enhances the bioavailability of nutrients through increased absorption.*

Label (click image to enlarge)


As a dietary supplement take one (1) capsule a day with water.


Use only as directed. Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical conditions or use prescription medications. For adult use only.

Other Ingredients

Gelatin, Cellulose, Magnesium Stearate, titanium dioxide, FD&C Blue #1


Keep product at room temperature and humidity(59-86F, 40% RH).
Distributed by Direct Digital LLC, Charlotte, NC 28202
ApresFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas - Laila Nutra LLC. Internation patents pending.
UC-II® is a registered trademark of InterHealth N.I.
Bioperine® is registered trademark of Sabinsa Corp.

Nutrition Facts

Serving Size  1 Capsule
Servings Per Container  30

Amount Per Serving     % DV

Turmeric (rhizome)(standardized to min 95% curcuminoids)  200 mg   **
Resveratrol (from Polygonum cuspidatum root extract)  100 mg   **
Apresflex®-Boswellia serrata Extract (resin)  100 mg   **
UC-II® (10 mg total collagen, 3 mg undenatured type II collagen)  40 mg   **
Hyaluronic Acid (min 89%)  5 mg   **
Bioperine®-Black Pepper Extract (fruit)(standardized to min 95% piperine)  5 mg   **

** Daily Value (DV) not established.


4.0 / 5.0
58 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Stars
Probably one of the best products on the market.
I am so impressed with how much better my knees feel that I have ordered more of it. It really gives you a lot of relief.
January 6, 2018
1 month ago
Not sure yet. I still have pain, so I still can't make a recommendation.
January 6, 2018
1 month ago
Was headed toward knee replacement surgery when I started taking this product.Two years later no surgery and still skiing.
January 1, 2018
1 month ago
Ssurgery or Instaflex Advanced
I was headed for knee replacement - pain walking, aching while trying to sleep, 4-5 steps when got up before able to walk without stumbling. I worked in a medical field for over 30 years and was taught herbals were just placebos. Decided to try Instaflex Advanced as a last resort before surgery. Didn't expect much....but even a little relief would get me a little more time. The second day I had less pain! Each day got a little better. Do I still 'feel' my knees if I twist the wrong way? Yes. But, I can walk without limping, sleep without discomfort, and continue to play golf. Do I think this is a miracle cure? No. But it has relieved most of my pain, and allowed me to continue my daily activities for now. At some point in the future.....who knows.
December 6, 2017
1 month ago
This works!
November 27, 2017
2 months ago
Worth a try. I'm satisfied.
Instaflex taken with turmeric I now can sleep at night without any knee pain. I can also walk longer and farther also without pain. I'm a regular user.
November 16, 2017
2 months ago
Since I've been taking this, my knees have never felt better. Hopefully over time they will improve more. Only taking them for 2 weeks yet
October 31, 2017
3 months ago
I am on my second bottle and the pain in my knees is almost gone. Love it.
October 26, 2017
3 months ago
Worth your trial
I self test all OTC supplements by starting then stopping (evaluation results) and repeat the process. Instaflex passed my test In decreasing my knee soreness (stiffness) to a significant degree. Certainly for me much more effective than glucosamine and chondroitin.
What works for me may not for you, which I find true for all of this type of supplements
October 25, 2017
3 months ago
Great for knee pain !!!
Instaflex Advanced has helped my knee pain more than any other product I have tried. I am so thankful for it !!!!
October 23, 2017
3 months ago