Instaflex® Advanced | GNC

Instaflex® Advanced


Item # 452399


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Size: 30 Capsules

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Featuring UC-II® Collagen
Doctor Formulated
  • Relieve Discomfort*
  • Improve Flexibility*
  • Joint Relief in 7 Days*
One Small Capsule Daily

Regain Mobility with Instaflex Advanced Just one small capsule once a day can lead to more comfortable joints in as little as 7 days. CLINICAL STUDIES SHOW:
  • Aprèsflex® improves joint stiffness and discomfort by more than 60% when compared to placebo after 90 days.*
  • UC-II® Collagen significantly reduces knee discomfort and is twice as effective as glucosamine plus chondroitin.*
  • BioPerine® significantly enhances the bioavailability of nutrients through increased absorption.*

Label (click image to enlarge)


As a dietary supplement take one (1) capsule a day with water.


Use only as directed. Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical conditions or use prescription medications. For adult use only.

Other Ingredients

Gelatin, Cellulose, Magnesium Stearate, titanium dioxide, FD&C Blue #1


Keep product at room temperature and humidity(59-86F, 40% RH).
Distributed by Direct Digital LLC, Charlotte, NC 28202
ApresFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas - Laila Nutra LLC. Internation patents pending.
UC-II® is a registered trademark of InterHealth N.I.
Bioperine® is registered trademark of Sabinsa Corp.

Nutrition Facts

Serving Size  1 Capsule(s)
Servings Per Container  30

Amount Per Serving     % DV

Turmeric (rhizome)(standardized to min 95% curcuminoids)  200 mg   **
Resveratrol (from Polygonum cuspidatum root extract)  100 mg   **
Apresflex®-Boswellia serrata Extract (resin)  100 mg   **
UC-II® (10 mg total collagen, 3 mg undenatured type II collagen)  40 mg   **
Hyaluronic Acid (min 89%)  5 mg   **
Bioperine®-Black Pepper Extract (fruit)(standardized to min 95% piperine)  5 mg   **

** Daily Value (DV) not established.


4.1 / 5.0
65 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Stars
Give INSTAFLEX a Shot!
I have taken Osteo Bi-Flex, Triple Strength with Vitamin D, for years with excellent results for my painful 'Football Knees". Osteo Bi-Flex contained Glucosamine and Chondroitin. Within the last 6 months, Osteo Bi-Flex was no longer providing the needed relief for sore stiff knees. Switched to INSTAFLEX and within a week I found great relief. No more soreness or stiffness. Glad I switched!
February 14, 2018
Most Effective Knee Pain Relief
I have been using Instflex Advanced for two weeks and I am quite pleased. My knee pain has completely disappeared. I had been using glucosamine- chondroiton for 16 years and have discovered that Instaflex Advanced is much more effective.Better than Glucosamine
February 10, 2018
1 week ago
Starting my second week and see definite improvement looking forward to the next week
February 4, 2018
1 month ago
It’s good but it cost way too much!! I don’t know if I’ll be able to get another bottle!
January 31, 2018
1 month ago
Definitely a Must Try!
It has really improved my arthritis in my hands. I take
this along with Hyaluronic Acid + Chondroitin Sulfate.
I love this product!
I would definitely recommend it.
January 30, 2018
1 month ago
Nine days
I took it 9 days before my pain went away. And when I ran out the pain returned in 4 days, I will never run out again. I am a double amputtee, with pain in my sholders and hips from transfering myself. I also have bad knees and could not wear my legs. My acid reflex cleared up while taking this Instaflex Advanced. Phantam pain is mostly gone. So I do not take 6 Gabbypintan pils a day.
January 26, 2018
Instaflex Rocks!!
I absolutely Instaflex! I am enjoying so much more time with my grandson. Getting out of bed in the morning is no longer a chore. This product is great! I was advised that after knee surgery over a year ago that the next step would be a knee replacement. That was until I tried instaflex. Now I'm golden!! I tell everyone about this product....everyone!
January 17, 2018
1 month ago
Probably one of the best products on the market.
I am so impressed with how much better my knees feel that I have ordered more of it. It really gives you a lot of relief.
January 6, 2018
2 months ago
Not sure yet. I still have pain, so I still can't make a recommendation.
January 6, 2018
2 months ago
Was headed toward knee replacement surgery when I started taking this product.Two years later no surgery and still skiing.
January 1, 2018
2 months ago