Instaflex® Advanced | GNC

Instaflex® Advanced


Item # 452399


Size: 30 Capsules

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Featuring UC-II® Collagen
Doctor Formulated
  • Relieve Discomfort*
  • Improve Flexibility*
  • Joint Relief in 7 Days*
One Small Capsule Daily

Regain Mobility with Instaflex Advanced Just one small capsule once a day can lead to more comfortable joints in as little as 7 days. CLINICAL STUDIES SHOW:
  • Aprèsflex® improves joint stiffness and discomfort by more than 60% when compared to placebo after 90 days.*
  • UC-II® Collagen significantly reduces knee discomfort and is twice as effective as glucosamine plus chondroitin.*
  • BioPerine® significantly enhances the bioavailability of nutrients through increased absorption.*

Label (click image to enlarge)


As a dietary supplement take one (1) capsule a day with water.


Use only as directed. Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical conditions or use prescription medications. For adult use only.

Other Ingredients

Gelatin, Cellulose, Magnesium Stearate, titanium dioxide, FD&C Blue #1


Keep product at room temperature and humidity(59-86F, 40% RH).
Distributed by Direct Digital LLC, Charlotte, NC 28202
ApresFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas - Laila Nutra LLC. Internation patents pending.
UC-II® is a registered trademark of InterHealth N.I.
Bioperine® is registered trademark of Sabinsa Corp.

Nutrition Facts

Serving Size  1 Capsule
Servings Per Container  30

Amount Per Serving     % DV

Turmeric (rhizome)(standardized to min 95% curcuminoids)  200 mg   **
Resveratrol (from Polygonum cuspidatum root extract)  100 mg   **
Apresflex®-Boswellia serrata Extract (resin)  100 mg   **
UC-II® (10 mg total collagen, 3 mg undenatured type II collagen)  40 mg   **
Hyaluronic Acid (min 89%)  5 mg   **
Bioperine®-Black Pepper Extract (fruit)(standardized to min 95% piperine)  5 mg   **

** Daily Value (DV) not established.


3.8 / 5.0
32 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Stars
walking without pain!
I have tried this product for 2 months now and am totally thrilled with the results I am having. A year ago I was told I need both knees replaced. I refuse to put myself through that if not really necessary. So I gave this a try. I will continue purchasing this product. Wish it were a little less expensive though/
July 28, 2015
Instaflex Advanced
I have been taking the Advanced Instaflex for a couple of months. I was told I would need 2 knee replacements also.
I am having less pain and walking much better without knee
supports! I love this product and will continue to take it. A larger
quantity and less expensive would be great! Also, love the fact
of one pill daily.
August 23, 2015
Works as Advertised!
Was recommended to me and I was a bit skeptical, but I have to say it works. I run a lot and my knee soreness has disappeared as has general muscle tightness Highly recommend!
August 22, 2015
Walking never felt so good!!
I have been taking Instaflex for a little over a month now. It took about 2 weeks for me to notice any difference. Instaflex truly works and my Orthopedist told me to keep taking it since it has ingredients that are proven to relieve joint pain. I just wish it was less expensive though.
September 24, 2015
Really Relieved My Back Pain
I started taking this about 3 months ago and these pills are great I no longer take any pain pills don't wake up at night with a aching back and walking much easier I have arthritis of the spine and stenosis I would recommend these pills highly just wish they were a little cheaper but my gold card does help to reduce the price a little.
January 14, 2016
Joint pain worse than ever
This is supposed to show improvement in a week but, not only did that not happen, my joints hurt more than ever and it's been nearly a month. I stopped my normal routine of MSM + Glucosamine HCl to give this a try and now I'm trying to get restabilized. I sure wish I'd only bought 1 bottle instead of 2!!!
August 25, 2015
I have been taking these pills in one day will be a month. When I went to purchase them I could hardly walk. Now I am walking without the pain can even wear my heels again I am so thankful for finding this pill. It is a little pricey, but when it works it is well worth the money. Thanks to the Doctor that came up with miracle pill.

MARCH 17,2016
March 17, 2016
False promises
I tried it because it was supposed to show results in 7 days. So I thought the 14 day trial should tell me something. Absolutely no results!. All the good reviews say that they took it at least 1 month, mostly longer. If it is taking as long as other products they should advertise it that way.
May 23, 2016
Really works! No shellfish!
I have had minor issues with my knees for a long time & they were gradually getting worse. I especially noticed how stiff my knees were when I visit my daughter's house. She has a 2-story house & going up & down the steps is a necessity several times a day. When I first visited, I could barely navigate the stairs after a couple of days. Now, after taking InstaFlex for over a year, I can go up & down the stairs like a "normal" person! And for the whole 2-wk. visit! I can get in & out of my SUV easier, kneel easier & just plain move more easily! It took a couple of months before I noticed a difference, but it was definitely worth the wait! This product has no shellfish in it, which is hard to find when looking for a help for joints. SO glad I tried it! Won't be without it! (FYI: I'm 62)
December 5, 2016
Great product. Helps in managing knee pain. Recommend highly.
December 20, 2016

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