Instaflex® Advanced | GNC

Instaflex® Advanced


Item # 452399


Size: 30 Capsules

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Featuring UC-II® Collagen
Doctor Formulated
  • Relieve Discomfort*
  • Improve Flexibility*
  • Joint Relief in 7 Days*
One Small Capsule Daily

Regain Mobility with Instaflex Advanced Just one small capsule once a day can lead to more comfortable joints in as little as 7 days. CLINICAL STUDIES SHOW:
  • Aprèsflex® improves joint stiffness and discomfort by more than 60% when compared to placebo after 90 days.*
  • UC-II® Collagen significantly reduces knee discomfort and is twice as effective as glucosamine plus chondroitin.*
  • BioPerine® significantly enhances the bioavailability of nutrients through increased absorption.*

Label (click image to enlarge)


As a dietary supplement take one (1) capsule a day with water.


Use only as directed. Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical conditions or use prescription medications. For adult use only.

Other Ingredients

Gelatin, Cellulose, Magnesium Stearate, titanium dioxide, FD&C Blue #1


Keep product at room temperature and humidity(59-86F, 40% RH).
Distributed by Direct Digital LLC, Charlotte, NC 28202
ApresFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas - Laila Nutra LLC. Internation patents pending.
UC-II® is a registered trademark of InterHealth N.I.
Bioperine® is registered trademark of Sabinsa Corp.

Nutrition Facts

Serving Size  1 Capsule
Servings Per Container  30

Amount Per Serving     % DV

Turmeric (rhizome)(standardized to min 95% curcuminoids)  200 mg   **
Resveratrol (from Polygonum cuspidatum root extract)  100 mg   **
Apresflex®-Boswellia serrata Extract (resin)  100 mg   **
UC-II® (10 mg total collagen, 3 mg undenatured type II collagen)  40 mg   **
Hyaluronic Acid (min 89%)  5 mg   **
Bioperine®-Black Pepper Extract (fruit)(standardized to min 95% piperine)  5 mg   **

** Daily Value (DV) not established.


3.9 / 5.0
36 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Stars
The first bottle really made a difference in my pain levels and released a lot of pressure in my knees. As weeks go by I find myself needing to use a knee rub as well. But it is better than others I have used.

I would and have told some friends about Instaflex Advanced.
June 22, 2017
2 months ago
Advantage Plus Flexion
This works right for myself; I believe to be working it in.
June 7, 2017
1 month ago
INSTAFLEX ADVANCED - GREAT stuff -other instaflex variations, not so much
The Instaflex Advanced that contains turmeric & reservatrol SEEMS to help with my cervical spine pain! Just finishing my first bottle and have re-ordered - so time will tell. It's definitely worth trying for 3 to 6 months to see if it really helps!

BEWARE of other variations of Instaflex though. It was recommended that the product be purchased on-line, but I drove to my local GNC and purchased what I THOUGHT was the same thing - and it is completely different.

Be SURE to get the product that contains turmeric & reservatrol!!!
June 6, 2017
1 month ago
This product has made such a difference in my mobility. I can walk without staffing pain in my knee. The only two downsides: it's expensive at almost $2 per pill, and the name confusion on the regular brand. I bought the regular Instaflex the first time and was disappointed with the results. I hadn't realized they were different formulas. The advanced is wonderful! I signed up for the instant refills so I never have to worry about running out of product.
June 2, 2017
1 month ago
I feel like dancing again
Oh My God, let me tell you for the longest time I did not dance anymore I stopped walking for exercise because it hurt so much my knees were so stiff and swollen till I would only walk if I had to because I dreaded the pain and stiffness that i felt when I simply tried to take a step it would hurt so much. I started taking this product Instaflex just one pill a day and it only took me two days to start feeling the difference I mean really two days and I dont feel the pain and stiffness anymore I feel really good about this product and I wouldn't say it if I didn't mean it. If anyone is having some pain or even some stiffness in their joints just try Instaflex a really good product
March 31, 2017
It Works
I couldn't hardly walk, always limping and couldn't sleep, always in pain. Started the Instaflex Advanced and about 2-3 weeks later most of the pain was gone, I hardly limped at all, and I finally got a decent nights sleep. I have been on glucosomine and condroiton for years but my arthritis still caught up with me at the ripe age of 70. At least now I can get around - hope it continues to work now that I have been taking them for about 4 months.
March 31, 2017
Instaflex is the BEST Product on the Market
I have tried various products over the last few months to find relief for my knees. After trying the product I received enormous relief within the 1st 7 days and have decided to use this product going forward. While it is an expensive product I can purchase each of the ingredients separately if necessary with the exact same measures as listed. The cost separately means taking more than one pill a day. With this product I only take at night once a day and I am so relieved from the pain. Now I'm just waiting to see what my orthopedic doctor will have to saw about this product and my knees. So glad I found it. At one point I could not walk up more than 3 steps and now I can do steps again with only an annoyed paid but I don't have to pull myself up the steps anymore.
March 15, 2017
I haven't been taking this long enough to give my opinion yet
I took the 2 week sample and I'm almost half way through my 1st full bottle. I'm going to need more time before giving a true opinion.
March 14, 2017
Good Product
More relief from this product than from others that I have tried.
March 14, 2017
joint pain
some relief felt after only 3 weeks
March 14, 2017