Instaflex® Advanced | GNC

Instaflex® Advanced


Item # 452399


Size: 30 Capsules

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Featuring UC-II® Collagen
Doctor Formulated
  • Relieve Discomfort*
  • Improve Flexibility*
  • Joint Relief in 7 Days*
One Small Capsule Daily

Regain Mobility with Instaflex Advanced Just one small capsule once a day can lead to more comfortable joints in as little as 7 days. CLINICAL STUDIES SHOW:
  • Aprèsflex® improves joint stiffness and discomfort by more than 60% when compared to placebo after 90 days.*
  • UC-II® Collagen significantly reduces knee discomfort and is twice as effective as glucosamine plus chondroitin.*
  • BioPerine® significantly enhances the bioavailability of nutrients through increased absorption.*

Label (click image to enlarge)


As a dietary supplement take one (1) capsule a day with water.


Use only as directed. Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical conditions or use prescription medications. For adult use only.

Other Ingredients

Gelatin, Cellulose, Magnesium Stearate, titanium dioxide, FD&C Blue #1


Keep product at room temperature and humidity(59-86F, 40% RH).
Distributed by Direct Digital LLC, Charlotte, NC 28202
ApresFlex® is a registered trademark of Laila Nutraceuticals exclusively licensed to PL Thomas - Laila Nutra LLC. Internation patents pending.
UC-II® is a registered trademark of InterHealth N.I.
Bioperine® is registered trademark of Sabinsa Corp.

Nutrition Facts

Serving Size  1 Capsule
Servings Per Container  30

Amount Per Serving     % DV

Turmeric (rhizome)(standardized to min 95% curcuminoids)  200 mg   **
Resveratrol (from Polygonum cuspidatum root extract)  100 mg   **
Apresflex®-Boswellia serrata Extract (resin)  100 mg   **
UC-II® (10 mg total collagen, 3 mg undenatured type II collagen)  40 mg   **
Hyaluronic Acid (min 89%)  5 mg   **
Bioperine®-Black Pepper Extract (fruit)(standardized to min 95% piperine)  5 mg   **

** Daily Value (DV) not established.


4.0 / 5.0
52 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Stars
Worth a try. I'm satisfied.
Instaflex taken with turmeric I now can sleep at night without any knee pain. I can also walk longer and farther also without pain. I'm a regular user.
November 16, 2017
3 weeks ago
Since I've been taking this, my knees have never felt better. Hopefully over time they will improve more. Only taking them for 2 weeks yet
October 31, 2017
1 month ago
I am on my second bottle and the pain in my knees is almost gone. Love it.
October 26, 2017
1 month ago
Worth your trial
I self test all OTC supplements by starting then stopping (evaluation results) and repeat the process. Instaflex passed my test In decreasing my knee soreness (stiffness) to a significant degree. Certainly for me much more effective than glucosamine and chondroitin.
What works for me may not for you, which I find true for all of this type of supplements
October 25, 2017
1 month ago
Great for knee pain !!!
Instaflex Advanced has helped my knee pain more than any other product I have tried. I am so thankful for it !!!!
October 23, 2017
1 month ago
The best pain reliever I've ever tried, this is a true statement from a 65 year old black female.
I tried the 14 day free sample and within two days I could feel the difference, it does work!!! I recommend that anyone with knee pain try this product, maybe it doesn't work for everyone; but I don't have have cartilage in my Knee's and it has relieved my constant pain.
October 22, 2017
I just finished up taking a ten day sample of this new product. I simply can't believe how much improved my knees are. I was at the point of not being able to walk, and had to keep sitting in my recliner to get relief.

This is a great product and I highly recommend it. Although I'm a senior citizen on live on a limited income I have to find a way to keep purchasing this product.
October 17, 2017
Works great
September 19, 2017
5 months ago
It works. Try it
I've had cortisone shots. Monovisc injections. Had surgery for a torn meniscus. None of this stuff worked. I need a knee replacement. I come across instaflex advance. I started taking it and within two weeks my pain is gone. Thankyou Instaflex advance. It works. Gary M
September 18, 2017
I feel the price is way to high for what you get. I haven't experienced any change in my symptoms since I started using the product. Maybe I need to take it for a longer time. I'm not impressed.
August 7, 2017
4 months ago