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GNC TriFlex™ Fast-Acting

GNC TriFlex™ Fast-Acting
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GNC TriFlex™ Fast-Acting

240 Caplets

281422

Price: $66.99

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Description
  • Now with a joint cushioning blend including hyaluronic acid and vitamin C*
  • Maximum strength fast-acting support - works in days
  • Clinical strength for daily long-term useJoint comfort in days with GNC TriFlex™ Fast-Acting. This premium formula combines the full, clinically-tested amounts of glucosamine (1500 mg) and chondroitin (1200 mg) with a proprietary Fast-Acting Blend plus MSM to support joint comfort and flexibility and hyaluronic acid to help cushion joints.*
  • Clinically studied doses of glucosamine and chondroitin combined with MSM and proprietary herbal blend, which is shown to improve joint comfort and function.
  • Glucosamine and Chondroitin are natural building block components found in connective tissues and joint cartilage. Scientific research has shown that these building block compounds help to support the body's natural ability to regenerate cartilage and lubricate joints thus supporting joint health integrity and function.
  • Hyaluronic acid is an important structural component of body tissue, including the fluids surrounding the joints and collagen. Hyaluronic acid has the capacity to hold water, cushion joints and maintain the elastic integrity of skin.
  • Vitamin C is involved in the synthesis of collage.

  • * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
    Supplement Facts
    As a dietary supplement, take four caplets daily preferably with meals.
    Serving Size   4 Caplets
    Servings Per Container  60
    Amount Per Serving   % DV
    Sodium    130.00 mg   5% 
    Vitamin C (as Ascorbic Acid)    30.00 mg   50% 
    Glucosamine Hydrochiorde    1500.00 mg   ** 
    Chondroitin Sulfate Sodium    1200.00 mg   ** 
    MSM (Methylsulfonyl-methane)    250.00 mg   ** 
    Fast-Acting Comfort Blend    250.00 mg   ** 
     Chinese Skullcap Root Extract (Scutellaria baicalensis)        ** 
     Clutch Tree Wood& Bark Extract (Acacia catechu)        ** 
    Hyaluronic Acid (HA) (as Sodium Hyaluronate)    5.00 mg   ** 
     ** Daily Value (DV) not established

    Other Ingredients:  Cellulose, Titanium Dioxide (Natural Mineral Whitener), Vegetable Acetoglycerides, Natural Vanilla Flavor, Riboflavin, Sucralose

    No Sugar, No Artificial Colors, No Artificial Flavors, No Preservatives,No Wheat, No Gluten, No Soy, No Dairy, Yeast Free.

    Storage Instructions:  Store in a cool, dry place.

    Warning:  Keep out of reach of children



    Consult your physician prior to using this product if you are pregnant, nursing, taking medication, under 18 years of age or have a medical condition. Discontinue use two weeks prior to surgery.

    CONTAINS: Crustaceans (Shrimp)

    GNC Quality Commitment
    GNC is the leader in the development and manufacture of dietary supplements, committed to producing the highest quality products available. This commitment begins with quality designed supplement formulations. Every raw material that goes into a GNC supplement is guaranteed as to quality and potency. Each product is dated and then shipped immediately, so you can be sure you are purchasing the freshest supplements available. At GNC, we extend our quality commitment to you by offering our money-back guarantee.

    GNC Guarantee
    If you are not 100% completely satisfied, return the unused portion of the product with proof of purchase to your GNC store for a complete refund of your purchase price. No questions asked!

    Distributed by: General Nutrition Corporation Pittsburgh, Pa 15222
    Health Notes

    Joint Health

    Joint Health
    • Reliable and relatively consistent scientific data showing a substantial health benefit.
    • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
    • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

    Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

    For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

    Chondroitin SulfateStudies have shown that chondroitin may reduce pain, increase joint mobility, and promote healing in joints. It may also promote healing after injury giving the body the raw materials needed to manufacture molecules that help make up skin, tendons, ligaments, and joints.See Related Conditions (1)Close
    Osteoarthritis
    Dose: 800 to 1,200 mg a day
    Many trials have shown that supplementing with chondroitin sulfate reduces pain, increases joint mobility, and promotes healing within the joints.(more)
    Methylsulfonylmethane (MSM)In people with osteoarthritis of the knee, MSM has been associated with reduced pain and improved physical functioning.See Related Conditions (1)Close
    Osteoarthritis
    Dose: 2.25 to 6.0 grams per day
    In one trial, supplementing with methyl-sulfonylmethane significantly reduced pain and improved overall physical functioning in patients with osteoarthritis of the knee. (more)
    Glucosamine HydrochloridePreliminary research has suggested that glucosamine hydrochloride may help reduce pain and improve other symptoms in people with rheumatoid and osteoarthritis.See Related Conditions (1)Close
    Osteoarthritis
    Dose: Refer to label instructions
    Studies have shown glucosamine hydrochloride to be effective at reducing pain and improving symptoms in people with osteoarthritis.(more)
    Osteoarthritis
    Dose: 800 to 1,200 mg a day

    Chondroitin sulfate (CS) is a major component of the lining of joints. The structure of CS includes molecules related to glucosamine sulfate. CS levels have been reported to be reduced in joint cartilage affected by osteoarthritis. Possibly as a result, CS supplementation may help restore joint function in people with osteoarthritis.1 On the basis of preliminary evidence, researchers had believed that oral CS was not absorbed in humans;2 as a result, early double-blind CS research was done mostly by giving injections.3, 4 This research documented clinical benefits from CS injections. It now appears, however, that a significant amount of CS is absorbable in humans,5 though dissolving CS in water leads to better absorption than swallowing whole pills.6

    Strong clinical evidence now supports the use of oral CS supplements for osteoarthritis. Many double-blind trials have shown that CS supplementation consistently reduces pain, increases joint mobility, and/or shows evidence (including X-ray changes) of healing within joints of people with osteoarthritis.7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17 Most trials have used 400 mg of CS taken two to three times per day. One trial found that taking the full daily amount (1,200 mg) at one time was as effective as taking 400 mg three times per day.18 Reduction in symptoms typically occurs within several months.

    References

    1. Kerzberg EM, Roldan EJA, Castelli G, Huberman ED. Combination of glycosaminoglycans and acetylsalicylic acid in knee osteoarthritis. Scand J Rheum 1987;16:377.

    2. Baici A, Horler D, Moser B, et al. Analysis of glycosaminoglycans in human serum after oral administration of chondroitin sulfate. Rheumatol Int 1992;12:81-8.

    3. Kerzberg EM, Roldan EJA, Castelli G, Huberman ED. Combination of glycosaminoglycans and acetylsalicylic acid in knee osteoarthrosis. Scand J Rheumatol 1987;16:377-80.

    4. Rovetta G. Galactosaminoglycuronoglycan sulfate (Matrix) in therapy of tibiofibular osteoarhtirits of the knee. Drugs Exptl Clin Res 1991;17:53-7.

    5. Conte A, Volpi N, Palmieri L, et al. Biochemical and pharmacokinetic aspects of oral treatment with chondroitin sulfate. Arzneimittelforschung 1995;45:918-25.

    6. Ronca F, Palmieri L, Panicucci P, Ronca G. Anti-inflammatory active of chondroitin sulfate. Osteoarthritis Cartilage 1998;6(Suppl A):14-21.

    7. Uebelhart D, Thonar EJ, Delmas PD, et al. Effects of oral chondroitin sulfate on the progression of knee osteoarthritis: a pilot study. Osteoarthritis Cartilage 1998;6(Suppl A):39-46.

    8. Verbruggen G, Goemaere S, Veys EM. Chondroitin sulfate: S/DMOAD (structure/disease modifying anti-osteoarthritis drug) in the treatment of finger joint OA. Osteoarthritis Cartilage 1998;6(Suppl A):37-8.

    9. Bucsi L, Poor G. Efficacy and tolerability of oral chondroitin sulfate as a symptomatic slow-acting drug for osteoarthritis (SYSADOA) in the treatment of knee osteoarthritis. Osteoarthritis Cartilage 1998;6(Suppl A):31-6.

    10. Bourgeois P, Chales G, Dehais J, et al. Efficacy and tolerability of chondroitin sulfate 1200 mg/day vs chondroitin sulfate 3X400 mg/day vs placebo. Osteoarthritis Cartilage 1998;6(Suppl A):25-30.

    11. Pipitone V, Ambanelli U, Cervini C, et al. A multicenter, triple-blind study to evaluate galactosaminoglucuronoglycan sulfate versus placebo in patients with femorotibial gonarthritis. Curr Ther Res 1992;52:608-38.

    12. Bazieres B, Loyau G, Menkes CJ, et al. Le chondroitine sulfate dans le traitement de la gonarthrose et de la coxarthrose. Rev Rhum Mal Osteoartic 1992;59:466-72 [in French].

    13. Conrozier T, Vignon E. Die Wirkung von Chondroitinsulfat bei der Behandlung der Huft Gelenksarthrose. Eine Doppelblindstudie gegen Placebo. Litera Rheumatologica 1992;14:69-75 [in German].

    14. L'Hirondel JL. Klinische Doppelblind-Studie mit oral verabreichtem Chondroitinsulfat gegen Placebo bei der tibiofermoralen Gonarthrose (125 Patienten). Litera Rheumatologica 1992;14:77-82 [in German].

    15. Morreale P, Manopulo R, Galati M, et al. Comparison of the antiinflammatory efficacy of chondroitin sulfate and diclofenac sodium in patients with knee osteoarthritis. J Rheumatol 1996;23:1385-91.

    16. Leeb BF, Petera P, Neumann K. Results of a multicenter study of chondroitin sulfate (Condrosulf) use in arthroses of the finger, knee and hip joints. Wien Med Wochenschr 1996;146:609-14.

    17. Wildi LM, Raynauld JP, Martel-Pelletier J, et al. Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI. Ann Rheum Dis 2011;70:982-9.

    18. Bourgeois P, Chales G, Dehais J, et al. Efficacy and tolerability of chondroitin sulfate 1200 mg/day vs chondroitin sulfate 3X400 mg/day vs placebo. Osteoarthritis Cartilage 1998;6(Suppl A):25-30.

    Osteoarthritis
    Dose: 2.25 to 6.0 grams per dayAccording to a small double-blind trial, 2,250 mg per day of oral methylsulfonylmethane (MSM), a variant of DMSO, reduced osteoarthritis pain after six weeks.1 In another double-blind trial, supplementation with 3 grams of MSM twice a day for 12 weeks significantly reduced pain and improved overall physical functioning in patients with osteoarthritis of the knee.2
    References

    1. Lawrence RM. Methylsulfonylmethane (MSM): a double-blind study of its use in degenerative arthritis. Int J of Anti-Aging Med 1998;1:50.

    2. Kim LS, Axelrod LJ, Howard P, et al. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage 2006;14:286-94.

    Osteoarthritis
    Dose: Refer to label instructionsA few trials have evaluated glucosamine hydrochloride (GH), another form of glucosamine sulfate (GS), as a single remedy for osteoarthritis. One trial found only minor benefits from 1,500 mg per day of GH for 8 weeks in people with osteoarthritis of the knee.1 However, these people were also taking up to 4,000 mg per day of acetaminophen for pain relief, and that treatment might have masked a beneficial effect of GH. In another study, supplementing with GH (2,000 mg each morning for 12 weeks) significantly improved symptoms, compared with a placebo, in people with knee pain due to cartilage damage or osteoarthritis.2 In a four-week study from China, GH was as effective as GS in people with osteoarthritis of the knee.3 Another study found that the combination of GH and chondroitin sulfate was more effective than a placebo in people with moderate to severe knee pain from osteoarthritis, but not in those with mild pain.4 Despite the reported beneficial effects of GH, some investigators believe that the sulfate component of GS itself helps relieve osteoarthritis, and that GS would therefore be more effective than GH.
    References

    1. Houpt JB, McMillan R, Wein C, Paget-Dellio SD. Effect of glucosamine hydrochloride in the treatment of pain of osteoarthritis of the knee. J Rheumatol 1999;26:2423-30.

    2. Braham R, Dawson B, Goodman C. The effect of glucosamine supplementation on people experiencing regular knee pain. Br J Sports Med 2003;37:45-9.

    3. Qiu GX, Weng XS, Zhang K, et al. A multi-central, randomized, controlled clinical trial of glucosamine hydrochloride/sulfate in the treatment of knee osteoarthritis. Zhonghua Yi Xue Za Zhi 2005;85:3067-70 [in Chinese].

    4. Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 2006;795-808.

    Copyright 2013 Aisle7. All rights reserved. Aisle7.com

    The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2014.

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    Ratings and Reviews

    REVIEW SNAPSHOT®

    by PowerReviews
    GNC TriFlex™ Fast-Acting
     
    4.3

    (based on 29 reviews)

    92%

    of respondents would recommend this to a friend.

    Pros

    • Effective (21)
    • Easy to swallow (15)
    • Simple to take (15)
    • Easy on stomach (13)

    Cons

      Best Uses

      • Older people (15)
      • Daily use (9)
      • Men (9)
      • Women (7)
        • Reviewer Profile:
        • First time user (15), Health conscious (8)

      Reviewed by 29 customers

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      5.0

      Great product

      By chris5200

      from New Brunswick,NJ

      See all my reviews

      Pros

      • Effective

      Cons

        Best Uses

        • Older People

        Comments about GNC TriFlex™ Fast-Acting:

        My father really likes it. It is very effective. He feels better.

         
        4.0

        Triflex fast acting

        By tdoan

        from Saint Petersburg,FL

        About Me First Time User

        See all my reviews

        Pros

        • Easy To Swallow
        • Simple To Take

        Cons

          Best Uses

          • Older People

          Comments about GNC TriFlex™ Fast-Acting:

          It helps my knee and my joint feel better as I take it, but it is very expensive compare to the other products.

          (1 of 2 customers found this review helpful)

           
          3.0

          I would buy this product again and agai

          By 157634073

          from ROWLAND HEIGHTS,CA

          See all my reviews

          Comments about GNC TriFlex™ Fast-Acting:

          Things that are great about it

           
          4.0

          wd be better if cheaper

          By whbintexas

          from houston, tx

          About Me First Time User

          See all my reviews

          Pros

          • Effective

          Cons

          • Hard To Swallow

          Best Uses

          • Daily Use

          Comments about GNC TriFlex™ Fast-Acting:

          way too expensive.

          but effective.

          (1 of 1 customers found this review helpful)

           
          5.0

          What a difference this product has made

          By torreydwalker

          from Manvel, Texas

          About Me First Time User

          See all my reviews

          Pros

          • Easy on Stomach
          • Easy To Swallow
          • Effective
          • Simple To Take
          • Tastes Good

          Cons

            Best Uses

            • Daily Use

            Comments about GNC TriFlex™ Fast-Acting:

            TriFlex Fast Acting is an awesome natural product for joint pain! The GNC rep at (Pearland Town Center location) recommended it to me to assist with my lower back and hip pains I have been experiencing for over 10 years. He ensured me that this product would be very effective and beneficial in the process of elliminating my pain issue without any negative health side affects and he was so right! After about 3 days of taking this product I notice I was not experiencing any of pains I normally experienced each day. I now get out of bed and go throughout the day with little to no pain. The only issue I have is you must take a caplet (4) times a day and it would be great take only once a day. However, I have recommended this to friends and immediately they have all expressed what a difference this product has made with their various pains.

            (2 of 2 customers found this review helpful)

             
            5.0

            This Product Works!!

            By abbaclinic

            from Atlanta, GA

            About Me First Time User

            See all my reviews

            Pros

            • Easy on Stomach
            • Easy To Swallow
            • Effective
            • Simple To Take

            Cons

              Best Uses

              • Older People

              Comments about GNC TriFlex™ Fast-Acting:

              I have had osteoarthritis for 4 years. None of the NSAIDS have worked. My friend suggested that I take Triflex fast acting. I did. In 3 weeks, my pain is gone.!!

               
              5.0

              Great

              By tw2423

              from Manhattan,ny

              About Me First Time User

              See all my reviews

              Pros

              • Effective
              • Simple To Take

              Cons

                Best Uses

                • Men
                • Older People

                Comments about GNC TriFlex™ Fast-Acting:

                Great product, really help fix joint damage.

                (2 of 2 customers found this review helpful)

                 
                5.0

                very good

                By 744852683

                from usa

                About Me First Time User

                See all my reviews

                Verified Buyer

                Pros

                • Effective
                • Simple To Take

                Cons

                  Best Uses

                  • Older People
                  • Women

                  Comments about GNC TriFlex™ Fast-Acting:

                  this produce are great effective to my Arthritis

                  (0 of 2 customers found this review helpful)

                   
                  4.0

                  gnc triflex

                  By wchou48301

                  from MI

                  See all my reviews

                  Verified Buyer

                  Comments about GNC TriFlex™ Fast-Acting:

                  ok

                  (0 of 1 customers found this review helpful)

                   
                  5.0

                  Great item..

                  By seragood2000

                  from NJ

                  About Me First Time User

                  See all my reviews

                  Verified Buyer

                  Pros

                  • Effective

                  Cons

                  • Complicated To Take

                  Best Uses

                  • Men

                  Comments about GNC TriFlex™ Fast-Acting:

                  Great!!!!!!!!!!!

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