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GNC TriFlex™ Soft Chewables - Chocolate

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60 Chews

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Description
  • Delicious chocolate flavored soft chews offer a great-tasting alternative to hard to swallow tablets.
  • Combines glucosamine, a natural component found in connective tissues and joint cartilage with chondroitin and MSM.
  • Glucosamine and chondroitin provide many benefits:


  • Supports the body's natural ability to support joint tissue/function*

    Helps rebuild cartilage and lubricate joints*

    Support the body's ability to support joint health integrity*
  • Supports the body's natural ability to regenerate cartilage*
  • In addition to Glucosamine and Chondroitin this highly effective product also contains 25 mg of Lignisul MSM™ Methylsulfonyl-methane which is an organic sulfur found within connective tissues and joint cartilage.
  • * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    Supplement Facts

    As a dietary supplement for adults, take one soft chew two to three times a day, preferably with meals.

    Serving Size 1 Chews
    Servings Per Container 60
    Amount Per Serving % DV
    Calories 20.00
    Calories from Fat 5.00
    Total Fat 0.50 g 1%
    Sodium 10.00 mg 0%
    Total Carbohydrate 3.00 g 1%
    Sugars 2.00 g
    Glucosamine HCl 500.00 mg **
    Chondroitin Sulfate 400.00 mg **
    Methyl-sulfonyl-methane (MSM) 25.00 mg **
    ** Daily Value (DV) not established

    Other Ingredients: Corn Syrup, Sugar, Sweetened Condensed Skim Milk (Sugar, Skim Milk), Partially Hydrogenated Soybean Oil, Glucosamine HCl, Chondroitin Sulfate, Whey, Chocolate Liquor (Processed with Alkai), Mono and Diglycerides, Methyl-sulfonyl-methane (MSM), Soya Lecithin, Artificial Flavor

    Storage Instructions: To ensure freshness, reseal container after each use.

    Store at room temperature(55-85 degrees F.

    Warning: After opening, keep tightly closed in refrigerator or other cool place.

    Contains: Crustaceans (shrimp)

    This product contains ingredients derived from milk and soy.

    Lignisul MSM™ is licensed according to US Patents. Every shipment is tested by third-party laboratories to ensure purity and high-quality.

    Health Notes

    Joint Health

    Joint Health
    • Reliable and relatively consistent scientific data showing a substantial health benefit.
    • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
    • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

    Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

    For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

    Osteoarthritis
    Dose: 800 to 1,200 mg a day
    Many trials have shown that supplementing with chondroitin sulfate reduces pain, increases joint mobility, and promotes healing within the joints.(more)
    Osteoarthritis
    Dose: 2.25 to 6.0 grams per day
    In one trial, supplementing with methyl-sulfonylmethane significantly reduced pain and improved overall physical functioning in patients with osteoarthritis of the knee. (more)
    Osteoarthritis
    Dose: Refer to label instructions
    Studies have shown glucosamine hydrochloride to be effective at reducing pain and improving symptoms in people with osteoarthritis.(more)
    Osteoarthritis
    Dose: 800 to 1,200 mg a day

    Chondroitin sulfate (CS) is a major component of the lining of joints. The structure of CS includes molecules related to glucosamine sulfate. CS levels have been reported to be reduced in joint cartilage affected by osteoarthritis. Possibly as a result, CS supplementation may help restore joint function in people with osteoarthritis.1 On the basis of preliminary evidence, researchers had believed that oral CS was not absorbed in humans;2 as a result, early double-blind CS research was done mostly by giving injections.3, 4 This research documented clinical benefits from CS injections. It now appears, however, that a significant amount of CS is absorbable in humans,5 though dissolving CS in water leads to better absorption than swallowing whole pills.6

    Strong clinical evidence now supports the use of oral CS supplements for osteoarthritis. Many double-blind trials have shown that CS supplementation consistently reduces pain, increases joint mobility, and/or shows evidence (including X-ray changes) of healing within joints of people with osteoarthritis.7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17 Most trials have used 400 mg of CS taken two to three times per day. One trial found that taking the full daily amount (1,200 mg) at one time was as effective as taking 400 mg three times per day.18 Reduction in symptoms typically occurs within several months.

    References

    1. Kerzberg EM, Roldan EJA, Castelli G, Huberman ED. Combination of glycosaminoglycans and acetylsalicylic acid in knee osteoarthritis. Scand J Rheum 1987;16:377.

    2. Baici A, Horler D, Moser B, et al. Analysis of glycosaminoglycans in human serum after oral administration of chondroitin sulfate. Rheumatol Int 1992;12:81-8.

    3. Kerzberg EM, Roldan EJA, Castelli G, Huberman ED. Combination of glycosaminoglycans and acetylsalicylic acid in knee osteoarthritis. Scand J Rheum 1987;16:377.

    4. Rovetta G. Galactosaminoglycuronoglycan sulfate (Matrix) in therapy of tibiofibular osteoarhtirits of the knee. Drugs Exp Clin Res 1991;17:53-7.

    5. Conte A, Volpi N, Palmieri L, et al. Biochemical and pharmacokinetic aspects of oral treatment with chondroitin sulfate. Arzneimittelforschung 1995;45:918-25.

    6. Ronca F, Palmieri L, Panicucci P, Ronca G. Anti-inflammatory activity of chondroitin sulfate. Osteoarthritis Cartilage 1998;6(Supplement A):14-21.

    7. Uebelhart D, Thonar EJ, Delmas PD, et al. Effects of oral chondroitin sulfate on the progression of knee osteoarthritis: a pilot study. Osteoarthritis Cartilage 1998;6(Suppl A):39-46.

    8. Verbruggen G, Goemaere S, Veys EM. Chondroitin sulfate: S/DMOAD (structure/disease modifying anti-osteoarthritis drug) in the treatment of finger joint OA. Osteoarthritis Cartilage 1998;6(Suppl A):37-8.

    9. Bucsi L, Poor G. Efficacy and tolerability of oral chondroitin sulfate as a symptomatic slow-acting drug for osteoarthritis (SYSADOA) in the treatment of knee osteoarthritis. Osteoarthritis Cartilage 1998;6(Suppl A):31-6.

    10. Bourgeois P, Chales G, Dehais J, et al. Efficacy and tolerability of chondroitin sulfate 1200 mg/day vs chondroitin sulfate 3X400 mg/day vs placebo. Osteoarthritis Cartilage 1998;6(Suppl A):25-30.

    11. Pipitone V, Ambanelli U, Cervini C, et al. A multicenter, triple-blind study to evaluate galactosaminoglucuronoglycan sulfate versus placebo in patients with femorotibial gonarthritis. Curr Ther Res 1992;52:608-38.

    12. Bazieres B, Loyau G, Menkes CJ, et al. Le chondroitine sulfate dans le traitement de la gonarthrose et de la coxarthrose. Rev Rhum Mal Osteoartic 1992;59:466-72 [in French].

    13. Conrozier T, Vignon E. Die Wirkung von Chondroitinsulfat bei der Behandlung der Huft Gelenksarthrose. Eine Doppelblindstudie gegen Placebo. Litera Rheumatologica 1992;14:69-75 [in German].

    14. L'Hirondel JL. Klinische Doppelblind-Studie mit oral verabreichtem Chondroitinsulfat gegen Placebo bei der tibiofermoralen Gonarthrose (125 Patienten). Litera Rheumatologica 1992;14:77-82 [in German].

    15. Morreale P, Manopulo R, Galati M, et al. Comparison of the antiinflammatory efficacy of chondroitin sulfate and diclofenac sodium in patients with knee osteoarthritis. J Rheumatol 1996;23:1385-91.

    16. Leeb BF, Petera P, Neumann K. Results of a multicenter study of chondroitin sulfate (Condrosulf) use in arthroses of the finger, knee and hip joints. Wien Med Wochenschr 1996;146:609-14.

    17. Wildi LM, Raynauld JP, Martel-Pelletier J, et al. Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI. Ann Rheum Dis 2011;70:982-9.

    18. Bourgeois P, Chales G, Dehais J, et al. Efficacy and tolerability of chondroitin sulfate 1200 mg/day vs chondroitin sulfate 3X400 mg/day vs placebo. Osteoarthritis Cartilage 1998;6(Suppl A):25-30.

    Osteoarthritis
    Dose: 2.25 to 6.0 grams per dayAccording to a small double-blind trial, 2,250 mg per day of oral methylsulfonylmethane (MSM), a variant of DMSO, reduced osteoarthritis pain after six weeks.1 In another double-blind trial, supplementation with 3 grams of MSM twice a day for 12 weeks significantly reduced pain and improved overall physical functioning in patients with osteoarthritis of the knee.2
    References

    1. Lawrence RM. Methylsulfonylmethane (MSM): a double-blind study of its use in degenerative arthritis. Int J of Anti-Aging Med 1998;1:50.

    2. Kim LS, Axelrod LJ, Howard P, et al. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage 2006;14:286-94.

    Osteoarthritis
    Dose: Refer to label instructionsA few trials have evaluated glucosamine hydrochloride (GH), another form of glucosamine sulfate (GS), as a single remedy for osteoarthritis. One trial found only minor benefits from 1,500 mg per day of GH for 8 weeks in people with osteoarthritis of the knee.1 However, these people were also taking up to 4,000 mg per day of acetaminophen for pain relief, and that treatment might have masked a beneficial effect of GH. In another study, supplementing with GH (2,000 mg each morning for 12 weeks) significantly improved symptoms, compared with a placebo, in people with knee pain due to cartilage damage or osteoarthritis.2 In a four-week study from China, GH was as effective as GS in people with osteoarthritis of the knee.3 Another study found that the combination of GH and chondroitin sulfate was more effective than a placebo in people with moderate to severe knee pain from osteoarthritis, but not in those with mild pain.4 Despite the reported beneficial effects of GH, some investigators believe that the sulfate component of GS itself helps relieve osteoarthritis, and that GS would therefore be more effective than GH.5
    References

    1. Houpt JB, McMillan R, Wein C, Paget-Dellio SD. Effect of glucosamine hydrochloride in the treatment of pain of osteoarthritis of the knee. J Rheumatol 1999;26:2423-30.

    2. Braham R, Dawson B, Goodman C. The effect of glucosamine supplementation on people experiencing regular knee pain. Br J Sports Med 2003;37:45-9.

    3. Qiu GX, Weng XS, Zhang K, et al. A multi-central, randomized, controlled clinical trial of glucosamine hydrochloride/sulfate in the treatment of knee osteoarthritis. Zhonghua Yi Xue Za Zhi 2005;85:3067-70 [in Chinese].

    4. Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 2006;795-808.

    5. Hoffer LJ, Kaplan LN, Hamadeh MJ, et al. Sulfate could mediate the therapeutic effect of glucosamine sulfate. Metabolism 2001;50:767-70.

    Copyright 2014 Aisle7. All rights reserved. Aisle7.com

    The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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    Ratings and Reviews

    REVIEW SNAPSHOT®

    by PowerReviews
    GNC TriFlex™ Soft Chewables - Chocolate
     
    4.3

    (based on 21 reviews)

    90%

    of respondents would recommend this to a friend.

    Pros

    • Simple to take (16)
    • Increases flexibility (9)
    • Relieves pain (9)
    • Good value (7)
    • Effective (3)

    Cons

      Best Uses

      • Everyday use (11)
      • Older people (8)
      • Injury recovery (5)
      • Athletes (4)
        • Reviewer Profile:
        • Regular user (9), Health conscious (7), First time user (6)

      Reviewed by 21 customers

      Sort by

      Displaying reviews 1-10

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      5.0

      I buy this product again and again

      By vikingsfan52672

      from Hemet, CA

      About Me Regular User

      See all my reviews

      Pros

      • Increases Flexibility
      • Simple To Take

      Cons

        Best Uses

          Comments about GNC TriFlex™ Soft Chewables - Chocolate:

          My doctor recommended I take a Glucosamine, Chondroitin, and MSM supplement; I started off with the pills, but then decided to try the chews and I was pleasantly surprised at how tasty they are and easy to take! I thought they were a little funky at first as they have an almost tart flavor, and I think I was expecting more of a tootsie roll, but that doesn't mean they don't taste good! I have also tried the Peanut Butter flavor, and although I like it just fine, I have decided I like the chocolate flavor best. I couldn't say if they make a HUGE difference, but I have successfully recovered from knee surgery, so I can say it didn't hurt!

           
          5.0

          GNC TriFlex Soft Chewables- peanut butte

          By pojo242012

          from Virginia Beach, Virginia

          About Me Avoid Knee Surgery, Health Conscious, Regular User

          See all my reviews

          Pros

          • Enjoyable Daily Treat
          • Increases Flexibility
          • Relieves Pain
          • Simple To Take

          Cons

          • Pricey

          Best Uses

          • All Women Over 30
          • Athletes
          • Everyday Use
          • Injury Recovery
          • Older People

          Comments about GNC TriFlex™ Soft Chewables - Chocolate:

          I have loved Tri-Flex chewables from day #one be-
          cause they are tasty, easy to chew, no side effects. After 14 days of chewing one per day, I
          had -0- pain and could exercise, walk, climb
          stairs, etc. I do not participate in jogging
          and strenuous exercises such as high step dancing
          type routines and power aerobics------ ever--
          because I had the opinion that overdoing is bad
          for most people. And, now this is proving to be
          true as friends have terrible arthritis and are
          having surgery/while I am able to climb stairs,
          walk,+ use mild exercise equipment. I give credit
          to Tri-Flex chewables for keeping my knees and
          ankles + wrists and all of my joints in youth-
          ful working order. I have tried not taking this
          supplement for two weeks and found that I began
          to ache and limp around ! Now, I buy extra and
          have given as a gift to family and friends so
          they can enjoy flexibility as I do ! THANKS
          to GNC for stocking this fine product, which I
          have used for over five years. JP 11-6/'13

          (1 of 1 customers found this review helpful)

           
          4.0

          So far so good

          By rutzebeck4

          from FLA

          About Me First Time User

          See all my reviews

          Verified Buyer

          Pros

          • Good Value
          • Relieves Pain
          • Simple To Take

          Cons

            Best Uses

              Comments about GNC TriFlex™ Soft Chewables - Chocolate:

              Haven't been using very long but have noticed a slight improvement in my knee pain. Taste is not bad. I purchased both chocolate and peanut butter but have only tried the chocolate thus far.

               
              5.0

              GNC TriFlex Soft Chewables - Chocolate

              By brownfox263

              from Roseburg, OR

              About Me Regular User

              See all my reviews

              Verified Buyer

              Pros

              • Good Value
              • Increases Flexibility
              • Relieves Pain
              • Simple To Take

              Cons

                Best Uses

                • Everyday Use
                • Older People

                Comments about GNC TriFlex™ Soft Chewables - Chocolate:

                Regular price somewhat high but when on sale is a great buy.

                 
                1.0

                Inedible.

                By ajennerjahn

                from NY

                About Me Health Conscious

                See all my reviews

                Verified Buyer

                Pros

                  Cons

                  • Disgusting
                  • Horrible taste

                  Best Uses

                    Comments about GNC TriFlex™ Soft Chewables - Chocolate:

                    I tried one and couldn't even make myself finish it.unfortunately there is no way to give zero stars.

                    (1 of 1 customers found this review helpful)

                     
                    5.0

                    GREAT

                    By jr1476

                    from San Marcos, TX

                    See all my reviews

                    Verified Buyer

                    Pros

                    • Increases Flexibility
                    • Relieves Pain
                    • Simple To Take

                    Cons

                      Best Uses

                        Comments about GNC TriFlex™ Soft Chewables - Chocolate:

                        I have flat feet so I've never had the best joints. Since I've been working out my joints would ache and take longer to heal. After about 10 days of taking triflex chewables, my joints (especially my knees) feel 10 times better!

                        (1 of 1 customers found this review helpful)

                         
                        5.0

                        Works very well!

                        By jenna.archuleta

                        from Texas

                        About Me First Time User, Health Conscious

                        See all my reviews

                        Pros

                        • Effective
                        • Good Value
                        • Increases Flexibility
                        • Relieves Pain
                        • Simple To Take

                        Cons

                        • Taste

                        Best Uses

                        • Athletes
                        • Everyday Use
                        • Injury Recovery
                        • Older People

                        Comments about GNC TriFlex™ Soft Chewables - Chocolate:

                        I am very skeptical of vitamins. However, after reading the reviews, I was willing to give this product a shot. I am glad that I did! I am recovering from a torn rotator cuff, two torn ACL's & my knuckles pop all the time. I have noticed that after 2 weeks of use, my knuckles and knees do not pop or ache as much as they used to! My rotator cuff however is still bothersome. Also, the taste isn't the best. But I will still use the product despite the fact that the taste is strange. It is an excellent product!

                        (1 of 1 customers found this review helpful)

                         
                        4.0

                        Have been using GNC Chewables for years

                        By Jim757470

                        from Atlanta, GA

                        See all my reviews

                        Verified Buyer

                        Comments about GNC TriFlex™ Soft Chewables - Chocolate:

                        I have been using both the chocolate and peanut butter versions for years. I am no spring chicken but still work out vigorously (P90x which can test your joints and elyptical which is easier on the joints) several times a week so I like to think they help. Taking one with breakfast, lunch, and dinner also satisfies my need for any between meal snacks. Of course, like all supplements no way to be certain what the real impact is.

                        (3 of 3 customers found this review helpful)

                         
                        4.0

                        GNC Triflex Chewables are GREAT!

                        By daven

                        from Dayton, OH

                        About Me Athlete with bad joints, Health Conscious, Nerve damage from work

                        See all my reviews

                        Verified Buyer

                        Pros

                        • Good Value
                        • Relieves Pain
                        • Simple To Take

                        Cons

                          Best Uses

                          • Athletes
                          • Everyday Use
                          • Injury Recovery
                          • Older People

                          Comments about GNC TriFlex™ Soft Chewables - Chocolate:

                          The pills were too hard to swallow (sharp edges and HUGE) so I bought these chewables instead as a last resort. After a week or so of taking these, I experienced DRAMATIC changes to both my knees, neck and elbows (the original reason I started taking Tri-Flex) but also got relief from the pain in my wrists and forearms where my office work has created loss of feeling and dull pain. I am a believer! The chewables are great. I am skipping the huge "horse pill" versions for these from now on.

                          (1 of 1 customers found this review helpful)

                           
                          5.0

                          not only they're tasty but they help

                          By abasicman

                          from Hollywood, Fl

                          About Me Health Conscious, Regular User

                          See all my reviews

                          Verified Buyer

                          Pros

                          • Good Value
                          • Increases Flexibility
                          • Simple To Take

                          Cons

                            Best Uses

                            • Everyday Use
                            • Injury Recovery
                            • Older People

                            Comments about GNC TriFlex™ Soft Chewables - Chocolate:

                            not only they're tasty but they help my movement. This is the first bag and I'm gonna continue to take them

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