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GNC TriFlex™ Soft Chewables - Peanut Butter

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60 Chews

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Description
  • Delicious peanut butter flavored soft chews offer a great-tasting alternative to hard to swallow tablets.
  • Combines glucosamine, a natural component found in connective tissues and joint cartilage with chondroitin and MSM.
  • Glucosamine and chondroitin provide many benefits:


  • Supports the body's natural ability to support joint tissue/function*

    Helps rebuild cartilage and lubricate joints*

    Support the body's ability to support joint health integrity*
  • Supports the body's natural ability to regenerate cartilage*
  • In addition to Glucosamine and Chondroitin this highly effective product also contains 25 mg of Lignisul MSM™ Methylsulfonyl-methane which is an organic sulfur found within connective tissues and joint cartilage.
  • * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    Supplement Facts

    As a dietary supplement for adults, take one soft chew two to three times a day, preferably with meals.

    Serving Size 1 Chews
    Servings Per Container 60
    Amount Per Serving % DV
    Calories 20.00
    Calories from Fat 7.00
    Total Fat 0.80 g 1%
    Sodium 45.00 mg 2%
    Total Carbohydrate 3.00 g 1%
    Sugars 2.00 g
    Glucosamine HCl 500.00 mg **
    Chondroitin Sulfate 400.00 mg **
    Methyl-sulfonyl-methane (MSM) 25.00 mg **
    ** Daily Value (DV) not established

    Other Ingredients: Corn Syrup, Sugar, Peanut Butter, Sweetened Condensed Skim Milk (Sugar, Skim Milk), Partially Hydrogenated Soybean Oil, Glucosamine HCl, Chondroitin Sulfate, Whey, Mono and Diglycerides, Methyl-sulfonyl-methane (MSM), Soya Lecithin, Artificial Flavor

    Storage Instructions: To ensure freshness, reseal container after each use.

    Store at room temperature(55-85 degrees F.

    Warning: After opening, keep tightly closed in refrigerator or other cool place.

    Contains: Crustaceans (shrimp)

    This product contains ingredients derived from milk and soy.

    Contains peanuts.

    Lignisul MSM™ is licensed according to US Patents. Every shipment is tested by third-party laboratories to ensure purity and high-quality.

    Health Notes

    Joint Health

    Joint Health
    • Reliable and relatively consistent scientific data showing a substantial health benefit.
    • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
    • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

    Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

    For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

    Osteoarthritis
    Dose: 800 to 1,200 mg a day
    Many trials have shown that supplementing with chondroitin sulfate reduces pain, increases joint mobility, and promotes healing within the joints.(more)
    Osteoarthritis
    Dose: 2.25 to 6.0 grams per day
    In one trial, supplementing with methyl-sulfonylmethane significantly reduced pain and improved overall physical functioning in patients with osteoarthritis of the knee. (more)
    Osteoarthritis
    Dose: Refer to label instructions
    Studies have shown glucosamine hydrochloride to be effective at reducing pain and improving symptoms in people with osteoarthritis.(more)
    Osteoarthritis
    Dose: 800 to 1,200 mg a day

    Chondroitin sulfate (CS) is a major component of the lining of joints. The structure of CS includes molecules related to glucosamine sulfate. CS levels have been reported to be reduced in joint cartilage affected by osteoarthritis. Possibly as a result, CS supplementation may help restore joint function in people with osteoarthritis.1 On the basis of preliminary evidence, researchers had believed that oral CS was not absorbed in humans;2 as a result, early double-blind CS research was done mostly by giving injections.3, 4 This research documented clinical benefits from CS injections. It now appears, however, that a significant amount of CS is absorbable in humans,5 though dissolving CS in water leads to better absorption than swallowing whole pills.6

    Strong clinical evidence now supports the use of oral CS supplements for osteoarthritis. Many double-blind trials have shown that CS supplementation consistently reduces pain, increases joint mobility, and/or shows evidence (including X-ray changes) of healing within joints of people with osteoarthritis.7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17 Most trials have used 400 mg of CS taken two to three times per day. One trial found that taking the full daily amount (1,200 mg) at one time was as effective as taking 400 mg three times per day.18 Reduction in symptoms typically occurs within several months.

    References

    1. Kerzberg EM, Roldan EJA, Castelli G, Huberman ED. Combination of glycosaminoglycans and acetylsalicylic acid in knee osteoarthritis. Scand J Rheum 1987;16:377.

    2. Baici A, Horler D, Moser B, et al. Analysis of glycosaminoglycans in human serum after oral administration of chondroitin sulfate. Rheumatol Int 1992;12:81-8.

    3. Kerzberg EM, Roldan EJA, Castelli G, Huberman ED. Combination of glycosaminoglycans and acetylsalicylic acid in knee osteoarthritis. Scand J Rheum 1987;16:377.

    4. Rovetta G. Galactosaminoglycuronoglycan sulfate (Matrix) in therapy of tibiofibular osteoarhtirits of the knee. Drugs Exp Clin Res 1991;17:53-7.

    5. Conte A, Volpi N, Palmieri L, et al. Biochemical and pharmacokinetic aspects of oral treatment with chondroitin sulfate. Arzneimittelforschung 1995;45:918-25.

    6. Ronca F, Palmieri L, Panicucci P, Ronca G. Anti-inflammatory activity of chondroitin sulfate. Osteoarthritis Cartilage 1998;6(Supplement A):14-21.

    7. Uebelhart D, Thonar EJ, Delmas PD, et al. Effects of oral chondroitin sulfate on the progression of knee osteoarthritis: a pilot study. Osteoarthritis Cartilage 1998;6(Suppl A):39-46.

    8. Verbruggen G, Goemaere S, Veys EM. Chondroitin sulfate: S/DMOAD (structure/disease modifying anti-osteoarthritis drug) in the treatment of finger joint OA. Osteoarthritis Cartilage 1998;6(Suppl A):37-8.

    9. Bucsi L, Poor G. Efficacy and tolerability of oral chondroitin sulfate as a symptomatic slow-acting drug for osteoarthritis (SYSADOA) in the treatment of knee osteoarthritis. Osteoarthritis Cartilage 1998;6(Suppl A):31-6.

    10. Bourgeois P, Chales G, Dehais J, et al. Efficacy and tolerability of chondroitin sulfate 1200 mg/day vs chondroitin sulfate 3X400 mg/day vs placebo. Osteoarthritis Cartilage 1998;6(Suppl A):25-30.

    11. Pipitone V, Ambanelli U, Cervini C, et al. A multicenter, triple-blind study to evaluate galactosaminoglucuronoglycan sulfate versus placebo in patients with femorotibial gonarthritis. Curr Ther Res 1992;52:608-38.

    12. Bazieres B, Loyau G, Menkes CJ, et al. Le chondroitine sulfate dans le traitement de la gonarthrose et de la coxarthrose. Rev Rhum Mal Osteoartic 1992;59:466-72 [in French].

    13. Conrozier T, Vignon E. Die Wirkung von Chondroitinsulfat bei der Behandlung der Huft Gelenksarthrose. Eine Doppelblindstudie gegen Placebo. Litera Rheumatologica 1992;14:69-75 [in German].

    14. L'Hirondel JL. Klinische Doppelblind-Studie mit oral verabreichtem Chondroitinsulfat gegen Placebo bei der tibiofermoralen Gonarthrose (125 Patienten). Litera Rheumatologica 1992;14:77-82 [in German].

    15. Morreale P, Manopulo R, Galati M, et al. Comparison of the antiinflammatory efficacy of chondroitin sulfate and diclofenac sodium in patients with knee osteoarthritis. J Rheumatol 1996;23:1385-91.

    16. Leeb BF, Petera P, Neumann K. Results of a multicenter study of chondroitin sulfate (Condrosulf) use in arthroses of the finger, knee and hip joints. Wien Med Wochenschr 1996;146:609-14.

    17. Wildi LM, Raynauld JP, Martel-Pelletier J, et al. Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI. Ann Rheum Dis 2011;70:982-9.

    18. Bourgeois P, Chales G, Dehais J, et al. Efficacy and tolerability of chondroitin sulfate 1200 mg/day vs chondroitin sulfate 3X400 mg/day vs placebo. Osteoarthritis Cartilage 1998;6(Suppl A):25-30.

    Osteoarthritis
    Dose: 2.25 to 6.0 grams per dayAccording to a small double-blind trial, 2,250 mg per day of oral methylsulfonylmethane (MSM), a variant of DMSO, reduced osteoarthritis pain after six weeks.1 In another double-blind trial, supplementation with 3 grams of MSM twice a day for 12 weeks significantly reduced pain and improved overall physical functioning in patients with osteoarthritis of the knee.2
    References

    1. Lawrence RM. Methylsulfonylmethane (MSM): a double-blind study of its use in degenerative arthritis. Int J of Anti-Aging Med 1998;1:50.

    2. Kim LS, Axelrod LJ, Howard P, et al. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage 2006;14:286-94.

    Osteoarthritis
    Dose: Refer to label instructionsA few trials have evaluated glucosamine hydrochloride (GH), another form of glucosamine sulfate (GS), as a single remedy for osteoarthritis. One trial found only minor benefits from 1,500 mg per day of GH for 8 weeks in people with osteoarthritis of the knee.1 However, these people were also taking up to 4,000 mg per day of acetaminophen for pain relief, and that treatment might have masked a beneficial effect of GH. In another study, supplementing with GH (2,000 mg each morning for 12 weeks) significantly improved symptoms, compared with a placebo, in people with knee pain due to cartilage damage or osteoarthritis.2 In a four-week study from China, GH was as effective as GS in people with osteoarthritis of the knee.3 Another study found that the combination of GH and chondroitin sulfate was more effective than a placebo in people with moderate to severe knee pain from osteoarthritis, but not in those with mild pain.4 Despite the reported beneficial effects of GH, some investigators believe that the sulfate component of GS itself helps relieve osteoarthritis, and that GS would therefore be more effective than GH.5
    References

    1. Houpt JB, McMillan R, Wein C, Paget-Dellio SD. Effect of glucosamine hydrochloride in the treatment of pain of osteoarthritis of the knee. J Rheumatol 1999;26:2423-30.

    2. Braham R, Dawson B, Goodman C. The effect of glucosamine supplementation on people experiencing regular knee pain. Br J Sports Med 2003;37:45-9.

    3. Qiu GX, Weng XS, Zhang K, et al. A multi-central, randomized, controlled clinical trial of glucosamine hydrochloride/sulfate in the treatment of knee osteoarthritis. Zhonghua Yi Xue Za Zhi 2005;85:3067-70 [in Chinese].

    4. Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 2006;795-808.

    5. Hoffer LJ, Kaplan LN, Hamadeh MJ, et al. Sulfate could mediate the therapeutic effect of glucosamine sulfate. Metabolism 2001;50:767-70.

    Copyright 2014 Aisle7. All rights reserved. Aisle7.com

    The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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    Ratings and Reviews

    REVIEW SNAPSHOT®

    by PowerReviews
    GNC TriFlex™ Soft Chewables - Peanut Butter
     
    4.1

    (based on 21 reviews)

    81%

    of respondents would recommend this to a friend.

    Pros

    • Simple to take (17)
    • Good value (15)
    • Increases flexibility (12)
    • Relieves pain (9)
    • Increases strength (5)

    Cons

      Best Uses

      • Everyday use (15)
      • Older people (11)
      • Injury recovery (9)
      • Athletes (8)
        • Reviewer Profile:
        • Regular user (12), First time user (6), Health conscious (4)

      Reviewed by 21 customers

      Sort by

      Displaying reviews 1-10

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      5.0

      triflex chews

      By anaclement

      from stratham,nh

      About Me Regular User

      See all my reviews

      Pros

      • Good Value
      • Increases Flexibility
      • Increases Strength
      • Relieves Pain
      • Simple To Take

      Cons

        Best Uses

        • Everyday Use
        • Older People

        Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

        great flavor and easy to use

         
        5.0

        Good product

        By Davidbrand34

        from Beavercreek, Oh

        About Me Regular User

        See all my reviews

        Pros

        • Greattriflexhews

        Cons

          Best Uses

          • Everyday Use

          Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

          Really has helped my joints. Was skeptical at first but does work.

           
          3.0

          Good Product, horrible shipping time

          By kirkbergeron

          from Morgan City, LA

          About Me First Time User

          See all my reviews

          Pros

          • Good Value
          • Simple To Take

          Cons

            Best Uses

            • Injury Recovery

            Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

            This is a good product, but has one of the worst shipping delays and time I have ever seen from any online product, if you want this im a timely fashion do yourself a favor and go to the store personally, if you're waiting for it to be shipped to you, expect anywhere from a week to 2 weeks time. If you buy online expect a LONG delay, if you expect it sooner, then do yourself a favor and go to a store personally.

            (2 of 3 customers found this review helpful)

             
            4.0

            I like this product

            By Bustden

            from Pa

            See all my reviews

            Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

            I would recommend this product for dogs who have problems with their hips and legs and stuff due to arthritis. It seemed to help my dog and we give it to her every day.

             
            5.0

            Like em

            By wattfuller

            from Franklin, IN

            About Me First Time User

            See all my reviews

            Pros

            • Good Value
            • Increases Flexibility
            • Relieves Pain
            • Simple To Take

            Cons

              Best Uses

              • Athletes
              • Everyday Use

              Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

              I bought these after using another brand of glucosamine/chondroitin in pill form. I had many of the side effects except nausea. So I decided I should try the chews as they are easier on the stomach. I've taken them twice now & really like. They taste like a Werthers in chew form. I bought for fibromyalgia symptoms & knee pain after surgery a few yrs ago. Dr said I have early arthritis. I was nervous about trying this flavor because of some reviews but they aren't bad.

              (1 of 2 customers found this review helpful)

               
              4.0

              Great for Pets!

              By dlboxall

              from Raleigh, NC

              About Me Regular User

              See all my reviews

              Verified Buyer

              Pros

              • Good Value
              • Increases Flexibility
              • Simple To Take

              Cons

                Best Uses

                  Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

                  My dog loves the chewables and they really help when he's feeling stiff.

                   
                  5.0

                  Very Tasty and Helps

                  By gaylealstrom

                  from Staten Island, NY

                  About Me First Time User, Health Conscious

                  See all my reviews

                  Verified Buyer

                  Pros

                  • Good Value
                  • Relieves Pain
                  • Simple To Take

                  Cons

                  • Adds Calories To Diet

                  Best Uses

                  • Everyday Use
                  • Older People

                  Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

                  In this form TriFlex is delicious. It's like having a candy to finish off a meal, but it is also beneficial. I think it works just as well as taking TriFlex in pill form, if not better. In this form I have more confidence that it is being quickly absorbed. I eat one after every meal (3 a day)

                  (1 of 1 customers found this review helpful)

                   
                  3.0

                  Decent..

                  By bond.connie

                  from Long Beach, CA

                  About Me First Time User, Health Conscious

                  See all my reviews

                  Verified Buyer

                  Pros

                  • Good Value
                  • Simple To Take

                  Cons

                    Best Uses

                    • Athletes
                    • Everyday Use
                    • Injury Recovery
                    • Older People

                    Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

                    A friend recommended this brand and I saw that a chewable was offered so I decided to give it a try. The 1st taste was okay but it does have an after taste. Not a bad product though and I would buy it again.

                    (2 of 2 customers found this review helpful)

                     
                    5.0

                    Delicious

                    By stellman1

                    from Rockaway, NJ

                    About Me Health Conscious, Regular User

                    See all my reviews

                    Verified Buyer

                    Pros

                    • Easy On Stomach
                    • Easy to take swallow
                    • Good Value
                    • Increases Flexibility
                    • Simple To Take
                    • Tastes like candy

                    Cons

                      Best Uses

                      • Everyday Use
                      • Older People

                      Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

                      I take one in the morning and another in the evening. I look forward to my daily treat while giving my body a good suppliment

                      (0 of 2 customers found this review helpful)

                       
                      2.0

                      Some chews were wrong flavor

                      By chemeyer

                      from Hartland, Michigan

                      About Me Regular User

                      See all my reviews

                      Verified Buyer

                      Pros

                      • Simple To Take

                      Cons

                      • Doesn't Work

                      Best Uses

                      • Everyday Use

                      Comments about GNC TriFlex™ Soft Chewables - Peanut Butter:

                      I reported the mix up in flavors (chocolate is bad for dogs and we give them daily to our dogs). All I got was a complicated reply and no indication that they would resolve the issue. This is not the first time this has happened.

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