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GNC Pro Performance® HMB

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240 Tablets

Item #752821 See Product Details

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Description
  • Supports Muscle Health During Exercise
  • Supports Protein Synthesis
  • Patented Form – 1000 MG Per Serving
Resistance training in conjunction with HMB may improve protein synthesis. In addition, HMB plays a role in decreasing protein breakdown during resistance training. Pro Performance® HMB gives you pure HMB blended with Monopotassium Phosphate.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

As a dietary supplement, take four tablets three times a day with meals. Do not exceed recommended intake levels.

Serving Size 4 Tablets
Servings Per Container 60
Amount Per Serving % DV
Calcium Hydroxymethyl Butyrate Monohydrate (HMB) 1000.00 mg **
Monopotassium Phosphate 200.00 mg **
** Daily Value (DV) not established

Other Ingredients: Di-Calcium Phosphate, Cellulose, Vegetable Acetoglycerides

No Sugar, No Starch, No Artificial Color, No Artificial Flavors, No Preservatives, Sodium Free, No Wheat, No Gluten, No Corn, No Soy, No Dairy, Yeast Free

Storage Instructions: Store in a cool dry place.

Warning: After opening, keep tightly closed in refrigerator or other cool place.

Nutritional uses of Calcium B-Hydroxyl B-Methylbutyrate (HMB) are licensed to GNC under United States Patent No 5.348.979

Health Notes

HMB

HMB
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

High Cholesterol
Dose: 3 grams daily
Supplementing with HMB, or beta hydroxy-beta-methylbutyrate, is an effective way to lower total and LDL cholesterol. (more)
Obesity
Dose: 3 grams per day or 17 mg per pound of body weight per day
HMB may improve muscle growth and overall body composition when combined with an exercise program in people who are not already highly trained athletes.(more)
Athletic Performance and Improving Body Composition with Strength Training in Untrained People
Dose: 3 grams daily
HMB, a breakdown product of an essential branched-chain amino acid, has a role in protein synthesis and might, therefore, improve muscle growth and overall body composition. Research suggests it might be effective only when combined with an exercise program in people who are not already highly trained athletes.(more)
HIV and AIDS Support and Preservation of Lean Body Mass
Dose: 1.5 grams of HMB, 7 grams of L-glutamine, and 7 grams of L-arginine twice per day
The combination of glutamine, arginine, and HMB may prevent loss of lean body mass in people with AIDS-associated wasting.(more)
High Cholesterol
Dose: 3 grams dailyThe combined results of nine double-blind trials indicate that supplementing with HMB, or beta hydroxy-beta-methylbutyrate, effectively lowers total and LDL cholesterol.1 All trials used 3 grams per day, taken for three to eight weeks.
References

1. Nissen S, Sharp RL, Panton L, et al. beta-hydroxy-beta-methylbutyrate (HMB) supplementation in humans is safe and may decrease cardiovascular risk factors. J Nutr 2000;130:1937-45.

Obesity
Dose: 3 grams per day or 17 mg per pound of body weight per day

Biochemical and animal research show that HMB has a role in protein synthesis and might, therefore, improve muscle growth and overall body composition when given as a supplement. However, double-blind human research suggests that HMB may only be effective when combined with an exercise program in people who are not already highly trained athletes. Double-blind trials found no effect of 3 to 6 grams per day of HMB on body weight, body fat, or overall body composition in weight-training football players or other trained athletes.1, 2, 3, 4, 5 However, one double-blind study found that 3 grams per day of HMB increased the amount of body fat lost by 70-year old adults who were participating in a strength-training program for the first time.6 A double-blind study of young men with no strength-training experience reported greater improvements in muscle mass (but not in percentage body fat) when HMB was used in the amount of 17 mg per pound of body weight per day.7 However, another group of men in the same study given twice as much HMB did not experience any changes in body composition.

References

1. Ransone J, Neighbors K, Lefavi R, Chromiak J. The effect of beta-hydroxy beta-methylbutyrate on muscular strength and body composition in collegiate football players. J Strength Cond Res 2003;17:34-9.

2. Kreider R, Ferreira M, Wilson M, et al. Effects of calcium beta-HMB supplementation with or without creatine during training on body composition alterations. FASEB J 1997;11:A374 [abstract].

3. Slater G, Jenkins D, Logan P, et al. Beta-hydroxy-beta-methylbutyrate (HMB) supplementation does not affect changes in strength or body composition during resistance training in trained men. Int J Sport Nutr Exerc Metab 2001;11:384-96.

4. Kreider RB, Ferreira M, Wilson M, Almada AL. Effects of calcium beta-hydroxy-beta-methylbutyrate (HMB) supplementation during resistance-training on markers of catabolism, body composition and strength. Int J Sports Med 1999;20:503-9.

5. Slater GJ, Jenkins D. Beta-hydroxy-beta-methylbutyrate (HMB) supplementation and the promotion of muscle growth and strength. Sports Med 2000;30:105-16 [review].

6. Vukovich MD, Stubbs NB, Bohlken RM. Body composition in 70-year-old adults responds to dietary beta-hydroxy-beta-methylbutyrate similarly to that of young adults. J Nutr 2001;131:2049-52.

7. Gallagher PM, Carrithers JA, Godard MP, et al. Beta-hydroxy-beta-methylbutyrate ingestion, Part I: effects on strength and fat free mass. Med Sci Sports Exerc 2000;32:2109-15.

Athletic Performance and Improving Body Composition with Strength Training in Untrained People
Dose: 3 grams dailyHMB (beta hydroxy-beta-methylbutyrate) is a metabolite (breakdown product) of leucine, one of the essential branched-chain amino acids. Biochemical and animal research show that HMB has a role in protein synthesis and might, therefore, improve muscle growth and overall body composition when given as a supplement. However, double-blind human research suggests that HMB may only be effective when combined with an exercise program in people who are not already highly trained athletes. Double-blind trials found no effect of 3 to 6 grams per day of HMB on body weight, body fat, or overall body composition in weight-training football players or other trained athletes.1, 2, 3, 4, 5 However, one double-blind study found that 3 grams per day of HMB increased the amount of body fat lost by 70-year old adults who were participating in a strength-training program for the first time.6 A double-blind study of young men with no strength-training experience reported greater improvements in muscle mass (but not in percentage body fat) when HMB was used in the amount of 17 mg per pound of body weight per day.7 However, another group of men in the same study given twice as much HMB did not experience any changes in body composition.
References

1. Ransone J, Neighbors K, Lefavi R, Chromiak J. The effect of beta-hydroxy beta-methylbutyrate on muscular strength and body composition in collegiate football players. J Strength Cond Res 2003;17:34-9.

2. Kreider R, Ferreira M, Wilson M, et al. Effects of calcium beta-HMB supplementation with or without creatine during training on body composition alterations. FASEB J 1997;11:A374 [abstract].

3. Slater G, Jenkins D, Logan P, et al. Beta-hydroxy-beta-methylbutyrate (HMB) supplementation does not affect changes in strength or body composition during resistance training in trained men. Int J Sport Nutr Exerc Metab 2001;11:384-96.

4. Kreider RB, Ferreira M, Wilson M, Almada AL. Effects of calcium beta-hydroxy-beta-methylbutyrate (HMB) supplementation during resistance-training on markers of catabolism, body composition and strength. Int J Sports Med 1999;20:503-9.

5. Slater GJ, Jenkins D. Beta-hydroxy-beta-methylbutyrate (HMB) supplementation and the promotion of muscle growth and strength. Sports Med 2000;30:105-16 [review].

6. Vukovich MD, Stubbs NB, Bohlken RM. Body composition in 70-year-old adults responds to dietary beta-hydroxy-beta-methylbutyrate similarly to that of young adults. J Nutr 2001;131:2049-52.

7. Gallagher PM, Carrithers JA, Godard MP, et al. Beta-hydroxy-beta-methylbutyrate ingestion, Part I: effects on strength and fat free mass. Med Sci Sports Exerc 2000;32:2109-15.

HIV and AIDS Support and Preservation of Lean Body Mass
Dose: 1.5 grams of HMB, 7 grams of L-glutamine, and 7 grams of L-arginine twice per day

The combination of glutamine, arginine, and the amino acid derivative, hydroxymethylbutyrate (HMB), may prevent loss of lean body mass in people with AIDS-associated wasting. In a double-blind trial, AIDS patients who had lost 5% of their body weight in the previous three months received either placebo or a nutrient mixture containing 1.5 grams of HMB, 7 grams of L-glutamine, and 7 grams of L-arginine twice daily for eight weeks.1 Those supplemented with placebo gained an average of 0.37 pounds, mostly fat, but lost lean body mass. Those taking the nutrient mixture gained an average of 3 pounds, 85% of which was lean body weight.

References

1. Clark RH, Feleke G, Din M, et al. Nutritional treatment for acquired immunodeficiency virus-associated wasting using beta-hydroxy beta-methylbutyrate, glutamine, and arginine: a randomized, double-blind, placebo-controlled study. JPEN J Parenter Enteral Nutr 2000;24:133-9.

HMB (beta hydroxy-beta-methylbutyrate) is a metabolite of the essential amino acid leucine (one of the branched-chain amino acids).

Copyright 2015 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2016.

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