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GNC Total Lean™ Appetrex Control™

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60 Tablets

Item #968222 See Product Details

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Description
  • Clinically proven to reduce calorie intake
  • Boosts energy and metabolism

No more excuses - GNC Total Lean™ Appetrex Control™ is clinically shown to help control your appetite and reduce calorie intake when you need it most - at the start of your diet. This multi-action formula combines energizing herbs such as yerba mate extract and black tea with EGCG, a major thermogenic component of green tea that helps support metabolism. In addition, Appetrex Control supplies chromium that supports your metabolism by assisting insulin and important B vitamins to help your body use glucose more efficiently and metabolize fats, protein and carbohydrates. B vitamins also play an essential role in energy production; low energy levels are a key concern among dieters.

In a clinical study of 30 healthy adults (who took Appetrex Control one week followed by a placebo one week apart, or vice versa) food intake was reduced by nearly 10% when the subjects took Appetrex Control versus the placebo prior to their first meal at the start of their diet.

To help you manage your weight, we've included an easy-to-follow meal and exercise plan. Created by expert nutritionists and dietitians, this two-week meal plan provides you with 1,500 calories each day and features healthy foods.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

As a dietary supplement, take two tablets once daily with water 30 to 60 minutes before lunch or dinner. Do not take near bedtime.

Serving Size 2 Tablets
Servings Per Container 30
Amount Per Serving % DV
Thiamin (Vitamin B-1)(as Thiamin Mononitrate) 1.50 mg 100%
Riboflavin (Vitamin B-2) 1.70 mg 100%
Niacin 20.00 mg 100%
Vitamin B-6 (as Pyridoxine Hydrochloride) 2.00 mg 100%
Chromium (as Hydrolyzed Protein Chelate) 120.00 mcg 100%
Proprietary Herbal Blend 522.50 mg 0%
 Black Tea Leaves Extract (Camellia sinensis)*** **
 Coffee Bean Extract*** **
 Green Tea Leaves Extract (Camillia sinensis)(9.6% EGCG = 50mg)*** **
Yerba Mate Extract (Ilex paraguariensis)*** 500.00 mg 0%
Grape Skin Extract (Vitis vinifera) 210.00 mg 0%
Chrysin 200.00 mg 0%
Ginger Root Extract (Zingiber officinale) 200.00 mg 0%
Grape Seed Extract (Vitis vinifera) 125.00 mg 0%
Dill Weed Extract (Anethum graveolens) 5.00 mg 0%
** Daily Value (DV) not established

Other Ingredients: Di-Calcium Phosphate, Cellulose, Polyethylene Glycol, Vegetable Acetoglycerides, Titanium Dioxide (Natural Mineral Whitener), Caramel Color, Ethyl Vanillin

No Artificial Color, No Preservatives, Sodium Free, No Wheat, No Gluten, No Soy, No Dairy, Yeast Free

Storage Instructions: Store in a cool dry place.

Warning:

Consult your physician prior to using this product if you are pregnant, nursing, taking medication, under 18 years of age or have a medical condition. Discontinue use two weeks prior to surgery.

Keep out of reach of children

General Nutrition Corporation
Pittsburgh, PA 15222

Health Notes

Green Coffee Extract

Green Coffee Extract
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Hypertension
Dose: Extracts providing at least 50 mg per day chlorogenic acids
Extracts of green, unroasted coffee that are high in chlorogenic acids might help lower blood pressure. (more)
Obesity
Dose: Extract providing 400 to 450 mg of chlorogenic acids per day
Some research has suggested that green coffee extracts taken as supplements or in food may support weight loss. (more)
Type 2 Diabetes
Dose: Refer to label instructions
Drinking either regular or decaffeinated coffee has been associated with reduced type 2 diabetes risk in several preliminary human studies. (more)
Hypertension
Dose: Extracts providing at least 50 mg per day chlorogenic acids While drinking regular coffee or other sources of caffeine may slightly raise blood pressure,1 coffee also contains chlorogenic acids that may have a blood pressure-lowering effect, according to animal research.2 However, a double-blind study found that a substance produced by roasting coffee can inhibit this blood pressure-lowering effect, and by removing this substance, coffee lowered blood pressure.3 This suggests that extracts of unroasted ("green") coffee that are high in chlorogenic acids might help lower blood pressure. A double-blind trial found that eating soups containing green coffee extracts providing at least 50 mg per day chlorogenic acids lowered blood pressure significantly better than soup containing no green coffee extracts in people with mild hypertension, but that lower amounts of green coffee extracts in the soup were not effective.4 A double-blind trial of green coffee extract supplements containing 140 mg per day of chlorogenic acids reduced systolic blood pressure by an average of 10 mm Hg and diastolic blood pressure by an average of 7 mm Hg in people with mild hypertension.5 One controlled trial found no blood pressure-lowering effect of green coffee extract supplements in people with normal blood pressure.6
References

1. Noordzij M, Uiterwaal CS, Arends LR, et al. Blood pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials. J Hypertens 2005;23:921-8 [review].

2. Noordzij M, Uiterwaal CS, Arends LR, et al. Blood pressure response to chronic intake of coffee and caffeine: a meta-analysis of randomized controlled trials. J Hypertens 2005;23:921-8 [review].

3. Yamaguchi T, Chikama A, Mori K, et al. Hydroxyhydroquinone-free coffee: a double-blind, randomized controlled dose-response study of blood pressure. Nutr Metab Cardiovasc Dis 2008;18:408-14.

4. Kozuma K, Tsuchiya S, Kohori J, et al. Antihypertensive effect of green coffee bean extract on mildly hypertensive subjects. Hypertens Res 2005;28:711-8.

5. Watanabe T, Arai Y, Mitsui Y, et al. The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension. Clin Exp Hypertens 2006;28:439-49.

6. Ochiai R, Jokura H, Suzuki A, et al. Green coffee bean extract improves human vasoreactivity. Hypertens Res 2004;27:731-7.

Obesity
Dose: Extract providing 400 to 450 mg of chlorogenic acids per day Animal research suggests that green coffee extract and its major component, chlorogenic acid, may help with weight loss and reducing abdominal fat.1, 2 An uncontrolled human study found that people who drank 750 ml per day of coffee containing green coffee bean constituents for four weeks ate fewer calories and lost weight.3 In a controlled study, overweight people who drank a coffee beverage containing green coffee extract (providing 400 to 450 mg of chlorogenic acids per day) for 12 weeks lost an average of about 12 pounds and 3.6% body fat compared to less than 4 pounds and an insignificant amount of body fat lost by people who drank a similar amount of coffee without added green coffee extracts.4 Another controlled study reported a statistically significant 11 pound weight loss after 60 days when overweight people took 400 mg per day of green coffee extracts (providing 180 mg of chlorogenic acids per day), compared to about a five pound loss in people taking a placebo.5 The green coffee extracts group also significantly raised their ratio of lean body tissue to body fat compared to the control group. However, since these studies lasted only 12 weeks or less, more research is needed to determine if green coffee extract can help people accomplish long-term weight loss. In addition, at least one human study supporting green coffee extract's effect on weight loss has been retracted due to methodological problems, raising suspicion about research relating to green coffee extract and weight loss.
References

1. Cho AS, Jeon SM, Kim MJ, et al. Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice. Food Chem Toxicol 2010;48:937-43.

2. Shimoda H, Seki E, Aitani M. Inhibitory effect of green coffee bean extract on fat accumulation and body weight gain in mice. BMC Complement Altern Med 2006;6:9.

3. Bakuradze T, Boehm N, Janzowski C, et al. Antioxidant-rich coffee reduces DNA damage, elevates glutathione status and contributes to weight control: results from an intervention study. Mol Nutr Food Res 2011;55:793-7

4. Thom E. The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people J Int Med Res 2007;35:900-8.

5. Dellalibera O. Lemaire B, Lafay S. Svetol, green coffee extract, induces weight loss and increases the lean to fat mass ratio in volunteers with overweight problem. Phytotherapie 2006;4:194-7.

Type 2 Diabetes
Dose: Refer to label instructionsDrinking either regular or decaffeinated coffee has been associated with reduced type 2 diabetes risk in several preliminary human studies.1 Test tube studies suggest that chlorogenic acid, a primary constituent found in both coffee and in green coffee extract may inhibit glucose production by the liver,2 which could theoretically lead to lower blood sugar. An animal study found that green coffee extract also prevented the reduction in insulin sensitivity caused by a high-fat diet.3 No human studies have tested the effect of green coffee extract on reducing risk of diabetes or improving insulin sensitivity, but a double-blind trial found that healthy people who drank a sweetened coffee beverage containing green coffee extract (providing 400 to 450 mg of chlorogenic acids) had lower blood sugar during the following two hours compared to when they drank the same coffee beverage without added green coffee extract.4 More research is needed to determine whether green coffee extract can help prevent or treat type 2 diabetes.
References

1. Huxley R, Lee CM, Barzi F, et al. Coffee, decaffeinated coffee, and tea consumption in relation to incident type 2 diabetes mellitus: a systematic review with meta-analysis. Arch Intern Med 2009;169:2053-63 [review].

2. Henry-Vitrac C, Ibarra A, Roller M. Contribution of chlorogenic acids to the inhibition of human hepatic glucose-6-phosphatase activity in vitro by Svetol, a standardized decaffeinated green coffee extract. J Agric Food Chem 2010;58:4141-4.

3. Ho L, Varghese M, Wang J, et al. Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice. Nutr Neurosci 2012;15:37-45.

4. Thom E. The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people J Int Med Res 2007;35:900-8.

Parts Used & Where Grown

Coffee is grown extensively throughout the world for its seeds (or beans), especially in the warm regions of the Central and South America, Asia, Africa, and the Pacific Islands.

Copyright 2014 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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Ratings and Reviews

REVIEW SNAPSHOT®

by PowerReviews
GNC Total Lean™ Appetrex Control™
 
3.6

(based on 153 reviews)

78%

of respondents would recommend this to a friend.

Pros

  • Curbs appetite (113)
  • No side effects (77)
  • Boosts energy (70)
  • Weight loss (67)
  • Good value (51)

Cons

  • Bad flavor (51)
  • Tough to swallow (38)
  • Not effective (31)
  • Caused side effects (24)
  • Poor value (9)

Best Uses

  • Weight loss (85)
  • Everyday use (74)
  • Exercise and diet supplement (55)
  • Maintaining weight (38)
  • Women (33)
    • Reviewer Profile:
    • Exercise regularly (60), Overweight (55), Health conscious (45), Athletic (19), Health professional (10)

Reviewed by 153 customers

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Displaying reviews 1-10

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(3 of 4 customers found this review helpful)

 
3.0

Tried It - It Works

By mskjfowler

from New Orleans

About Me Exercise Frequently, Health Conscious, Overweight

See all my reviews

Pros

  • Boosts Energy
  • Curbs Appetite
  • No Side Effects

Cons

  • Poor Taste
  • Tough To Swallow

Best Uses

  • Weight Loss

Comments about GNC Total Lean™ Appetrex Control™:

This product does curb my appetite. I would probably lose weight if I took it daily. I have taken it mid-day when I started feeling that afternoon sleepy...it perks me up and I make it through to the end of the day. I'm seditary for the most part and this helps me either jump start the day...or picks me up in the after noon. But I've not lost any weight. Two pills per day, doesn't seem to be enough. But it works when taken.

(5 of 5 customers found this review helpful)

 
5.0

Curbs cravings and reduce appetite

By mariana.cordova

from Saudi Arabia

About Me Diabetic, Exercise Frequently

See all my reviews

Pros

  • Boosts Energy
  • Curbs Appetite
  • No Side Effects

Cons

  • Poor Taste

Best Uses

  • Everyday Use
  • Exercise and Diet Supplement
  • Weight Loss
  • Women

Comments about GNC Total Lean™ Appetrex Control™:

I take my pill after lunch ending afternoon because thats when I have my food cravings. It helps a lot to keep calm and control what I eat.

(6 of 6 customers found this review helpful)

 
4.0

great product

By wlara

from tampa, florida

About Me Athletic, Exercise Regularly

See all my reviews

Pros

  • Boosts Energy
  • Curbs Appetite
  • Curbs Cravings
  • Helped Lose Weight

Cons

  • Hard On Stomach
  • Tough To Swallow

Best Uses

  • Everyday Use
  • Exercise and Diet Supplement
  • Maintaining Weight
  • Weight Loss
  • Women

Comments about GNC Total Lean™ Appetrex Control™:

This pill really does work. I was looking for somenthing to help me with my night cravings of sugar and also for a product to help me loose acouple of extra pounds that I have been wanting to loose and this has helped. I started using it 2 weeks ago and have lost 4 lbs. The only problems that I have with them is that they are very hard on my stomach, therefore instead of taking 2 pills before lunch I will take 1 before lunch and another before dinner to see if that helps they are also huge to swallow but they do work. My night cravings have dissapeared which is awesome and I get that extra energy during my workouts. I am very happy with this product overall.

(0 of 7 customers found this review helpful)

 
1.0

Feel nothing, but hunger

By cata.chinchilla

from San Jose CR

About Me Exercise Frequently, Exercise Regularly

See all my reviews

Pros

    Cons

    • Not Effective

    Best Uses

      Comments about GNC Total Lean™ Appetrex Control™:

      Keep drinking it cause I bought it but I experiences no effect at all

      (2 of 2 customers found this review helpful)

       
      4.0

      Good product

      By aaiimmyy

      from jackson, tn

      About Me Exercise Regularly, Health Conscious, Overweight

      See all my reviews

      Pros

      • Boosts Energy
      • Curbs Appetite
      • Goes Down Easy

      Cons

        Best Uses

        • Everyday Use
        • Weight Loss

        Comments about GNC Total Lean™ Appetrex Control™:

        Found this product to be effective if one taken in am and one around 1pm with water and 30 minutes before a meal.

        (7 of 7 customers found this review helpful)

         
        5.0

        So far, So good

        By MLC825

        from Washington, DC

        About Me Athletic, Bodybuilder, Exercise Frequently, Health Conscious, Health Professional

        See all my reviews

        Pros

        • Boosts Energy
        • Curbs Appetite
        • Goes Down Easy
        • Good Value
        • Helped Lose Weight
        • No Side Effects

        Cons

          Best Uses

          • Everyday Use
          • Exercise and Diet Supplement
          • Maintaining Weight
          • Weight Loss

          Comments about GNC Total Lean™ Appetrex Control™:

          Love it! Gives me energy, makes me really consider what I'm eating, when I'm eating and how much I'm eating. I've had these urges to just eat and eat and eat and this is helping out a lot. I'm drinking much more water & liquids.

          (6 of 9 customers found this review helpful)

           
          1.0

          No Bueno

          By da1udzire

          from New York, NY

          See all my reviews

          Comments about GNC Total Lean™ Appetrex Control™:

          The Total Lean line is the only line of products that I use. Although, this one in particular was an epic fail unfortunately. It did not curb my appetite at all. As a matter of fact, 3/4 of the bottle is still sitting in my drawer. Skip this one.

          (11 of 12 customers found this review helpful)

           
          1.0

          Doesn't work

          By vicky_83ncat

          from Charlotte, NC

          See all my reviews

          Pros

            Cons

            • Not Effective

            Best Uses

              Comments about GNC Total Lean™ Appetrex Control™:

              I didn't expect this to perform miracles, but I did expect get some results from using this. I would never expect a pill to do everything, but this one did nothing. In fact, I think it made me even more hungry than usual! Luckily GNC has a great return policy and awesome customer service, so I had no issues when I returned it.

              (8 of 9 customers found this review helpful)

               
              1.0

              Can't use

              By Chemoangeljudie

              from Morrison, CO

              About Me Overweight

              See all my reviews

              Pros

                Cons

                • Caused Side Effects

                Best Uses

                  Comments about GNC Total Lean™ Appetrex Control™:

                  This made me very itchy and I had to take first thing in the morning - only one - or I couldn't get my body to relax enough to go to sleep at night. Won't be taking it any more!

                  (5 of 9 customers found this review helpful)

                   
                  4.0

                  Works for me

                  By tgsloan

                  from Columbia, MD

                  About Me Exercise Regularly, Overweight

                  See all my reviews

                  Pros

                  • Curbs Appetite
                  • Helped Lose Weight
                  • No Side Effects

                  Cons

                  • Poor Taste

                  Best Uses

                  • Weight Loss

                  Comments about GNC Total Lean™ Appetrex Control™:

                  Solid product with no side effects at least to me....but the taste needs some work

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