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Description


Excellent for bathing, showering, shaving and shampooing. Many loyal users have been telling us for generations how "wonder"ful it cleans, moisturizes and deodorizes. They have described it as being helpful in removing scales of Psoriasis, Dandruff, Eczema and other skin irritations. No added colors or fragrances.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

Other Ingredients: Coconut Oil, Palm Oil, Aqua (Purified Water), Vegetable Glycerin, Rolled Oats, essence of oatmeal

Formulated & Marketed by Grandpa Brands Company
1820 Airport Exchange Blvd. Erlanger, KY 41018

Health Notes

Pycnogenol

Pycnogenol
This nutrient has been used in connection with the following health goals
  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary "Star-Rating" system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Retinopathy
Dose: 120 to 150 mg per day
Preliminary and double blind studies have shown that daily supplementation with Pycnogenol may slow the progression of retinopathy and improve vision. (more)
Glaucoma
Dose: Refer to label instructions
In a preliminary study, supplementation with a product that provided Pycnogenol (a maritime pine bark extract) and a standardized bilberry extract significantly decreased intraocular pressure in people who had elevated intraocular pressure.(more)
Hypertension
Dose: 100 to 200 mg per day
Pycnogenol has been shown to reduce systolic blood pressure in people with mild hypertension. (more)
Chronic Venous Insufficiency
Dose: 150 to 300 mg per day
A controlled study reported that supplementing daily with Pycnogenol improved symptoms of chronic venous insufficiency and reduced associated leg swelling. (more)
Edema
Dose: 150 mg per day for chronic edema
(more)
Venous Thrombosis
Dose: For plane travel: 200 mg two to three hours before a flight, 200 mg six hours later, and 100 mg on the following day
People at risk for venous thrombosis during plane travel were shown a video explaining in-flight exercises to prevent venous thrombosis and also followed a regimen of Pycnogenol, which appears to reduce frequency of episodes of venous thrombosis.(more)
High Cholesterol
Dose: 150 mg per day
Preliminary research suggests that Pycnogenol may lower LDL cholesterol and raise HDL cholesterol in people with normal cholesterol levels.(more)
Retinopathy
Dose: 120 to 150 mg per day
Preliminary and double blind studies have shown that daily supplementation with Pycnogenol may slow the progression of retinopathy and improve vision. (more)
Type 2 Diabetes
Dose: 100 to 150 mg per day
Preliminary research has suggested that Pycnogenol might help lower blood sugar in people with type 2 diabetes and slow progression of complications such as retinopathy. (more)
Type 1 Diabetes, Diabetic Retinopathy, and Skin Ulcers
Dose: Refer to label instructions
(more)
Dysmenorrhea
Dose: 60 mg per day
Preliminary research and double-blind research has reported that pycnogenol may reduce severe abdominal and back pain during menses. (more)
Menopause
Dose: 60 to 200 mg per day
In a double-blind trial, perimenopausal women who took Pycnogenol experienced reduced menopause symptoms. (more)
Endometriosis
Dose: 60 mg per day
In a preliminary study, symptoms of endometriosis gradually declined when women took Pycnogenol. (more)
Pregnancy and Postpartum Support
Dose: 30 mg per day
In a controlled study, pregnant women who took Pycnogenol reported some relief of pain in the legs, pelvis, hip, and low back. (more)
Erectile Dysfunction
Dose: 120 mg daily
In one study of men with erectile dysfunction, supplementing with Pycnogenol improved erectile function. (more)
Male Infertility
Dose: Refer to label instructions
(more)
Dysmenorrhea
Dose: 60 mg per day
Preliminary research and double-blind research has reported that pycnogenol may reduce severe abdominal and back pain during menses. (more)
Endometriosis
Dose: 60 mg per day
In a preliminary study, symptoms of endometriosis gradually declined when women took Pycnogenol. (more)
Sunburn
Dose: 1.1 to 1.66 mg per 2.2 lbs (1 kg) of body weight per day during periods of high sun exposure
Proanthocyanidins (flavonoids found in pine bark, grape seed, and other plant sources) may increase the amount of ultraviolet rays necessary to cause sunburn. (more)
Skin Ulcers
Dose: 150 mg per day orally, along with topical application of 100 mg daily
In a controlled study, symptoms of diabetic skin ulcers improved in those treated with standard medications plus oral and topical Pycnogenol. (more)
Melasma
Dose: 75 mg per day
Preliminary research shows that melasma, a disorder of increased skin pigmentation, may be improved by Pycnogenol supplementation. (more)
Attention Deficit-Hyperactivity Disorder
Dose: 1 mg daily per 2.2 pounds body weight daily
Though another story did not find effect, one study reported that Pycnogenol reduced symptoms of hyperactivity and improved attention, coordination, and concentration after one month in a group of children with ADHD. (more)
Osteoarthritis
Dose: 100 to 150 mg per day
Double-blind research has shown that Pycnogenol may improve symptoms of osteoarthritis, including reducing pain and the use of pain-relieving medication and improving walking performance. (more)
Menopause
Dose: 60 to 200 mg per day
In a double-blind trial, perimenopausal women who took Pycnogenol experienced reduced menopause symptoms. (more)
Asthma
Dose: 1 mg per pound of body weight per day, in two divided doses
In one trial, supplementing with Pycnogenol improved lung function and asthma symptoms and reduced the need for rescue medication in children with asthma. (more)
Gingivitis
Dose: 6 pieces chewing gum per day containing 5 mg each
In a double blind trial, people with gingivitis who chewed six pieces daily of a gum had less gum bleeding and no additional plaque formation, compared with a placebo group. (more)
Hemorrhoids
Dose: 300 mg per day for four days followed by 150 mg per day for three days, with or without daily use of a 0.5% topical cream at the same time
(more)
Erectile Dysfunction
Dose: 120 mg daily
In one study of men with erectile dysfunction, supplementing with Pycnogenol improved erectile function. (more)
Age-Related Cognitive Decline
Dose: 150 mg per day
A study of healthy senior people reported that supplementing daily with Pycnogenol improved some measures of memory after three months, compared with a group taking a placebo. (more)
Age-Related Cognitive Decline
Dose: 150 mg per day
A study of healthy senior people reported that supplementing daily with Pycnogenol improved some measures of memory after three months, compared with a group taking a placebo. (more)
Pregnancy and Postpartum Support
Dose: 30 mg per day
In a controlled study, pregnant women who took Pycnogenol reported some relief of pain in the legs, pelvis, hip, and low back. (more)
Jet Lag
Dose: 150 mg per day for seven days, beginning two days before travel
In controlled studies, Pycnogenol taken for two days before and five days after air travel led to milder symptoms that lasted for a shorter period of time, compared with untreated control groups. (more)
Leg Cramps
Dose: Refer to label instructions
A preliminary study of people experiencing at least four episodes per week of leg cramps due to either athletic activity, circulatory disorders, or unknown causes reported that Pycnogenol significantly reduced cramping. (more)
Lupus
Dose: 60 to 120 mg per day
In a small, controlled study, Pycnogenol seemed to help decrease systemic lupus erythematosus activity, measured with a combination of signs, symptoms, and blood measurements. (more)
Retinopathy
Dose: 120 to 150 mg per day Preliminary and double blind studies have shown that Pycnogenol slows the progression of retinopathy and improves vision when given in typical amounts of 120 to 150 mg per day.
Glaucoma
Dose: Refer to label instructionsIn a preliminary study, supplementation with a product that provided daily 80 mg of Pycnogenol (a maritime pine bark extract) and 160 mg of a standardized bilberry extract for two months significantly decreased intraocular pressure in people who had elevated intraocular pressure.1
References

1. Steigerwalt RD, Gianni B, Paolo M, et al. Effects of Mirtogenol on ocular blood flow and intraocular hypertension in asymptomatic subjects. Mol Vis 2008;14:1288-92.

Hypertension
Dose: 100 to 200 mg per day In a small double-blind trial, 200 mg per day of Pycnogenol lowered systolic blood pressure by about 5 mmHg in a group of people with mild hypertension.1 Another double-blind trial found that 100 mg per day of Pycnogenol made it possible to significantly reduce the amount of blood pressure medication necessary to normalize blood pressure.2 In a controlled study, hypertensive patients with signs of early kidney dysfunction were treated with blood pressure medication and either 150 mg of Pycnogenol or placebo.3 After six months, the group receiving Pycnogenol had a greater reduction in diastolic blood pressure and improved in some measures of kidney function.
References

1. Hosseini, S, Lee, J, Sepulveda RT, Fagan T, et al. A randomized, double blind, placebo-controlled, prospective 16 week crossover study to determine the role of Pycnogenol(R) in modifying blood pressure in mildly hypertensive patients. Nutr.Res 2001;21:67-76.

2. Liu X, Wei J, Tan F, et al.. Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patients. Life Sci 2004;74:855-62

3. Cesarone MR, Belcaro G, Stuard S, et al. Kidney flow and function in hypertension: protective effects of pycnogenol in hypertensive participants--a controlled study. J Cardiovasc Pharmacol Ther 2010;15:41-6.

Chronic Venous Insufficiency
Dose: 150 to 300 mg per day A controlled study reported that 150 mg per day of Pycnogenol improved symptoms of chronic venous insufficiency (CVI) and reduced associated leg swelling.1 Double-blind trials have also found that 100 mg of Pycnogenol two to three times daily reduced symptoms of CVI and improved measurements of blood flow and pressure inside of the veins.2, 3 A controlled trial found that 150 mg per day of Pycnogenol was more effective for CVI than use of elastic stockings alone, but that a combination of the two was better than either treatment alone.4 Several preliminary studies of CVI have investigated pycnogenol in comparison to or combined with other flavonoid extracts. These studies reported that Pycnogenol (150 to 300 mg per day) was more effective than 1,000 mg per day of a flavonoid mixture of 90% diosmin and 10% hesperidin,5 that 360 mg per day of Pycnogenol was more effective than 600 mg per day of horse chestnut seed extract,6 and that a daily combination of 40 mg Pycnogenol and 940 mg hydroxyethylrutosides was more effective than 1,200 mg per day of hydroxyethylrutosides alone.7
References

1. Cesarone MR, Belcaro G, Rohdewald P, et al. Rapid relief of signs/symptoms in chronic venous microangiopathy with pycnogenol: a prospective, controlled study. Angiology 2006;57:569-76.

2. Petrassi C, Mastromarino A, Spartera C. PYCNOGENOL in chronic venous insufficiency. Phytomedicine 2000;7:383-8.

3. Arcangeli P. Pycnogenol in chronic venous insufficiency. Fitoterapia 2000;71:236-44.

4. Cesarone MR, Belcaro G, Rohdewald P, et al. Improvement of signs and symptoms of chronic venous insufficiency and microangiopathy with Pycnogenol(R): A prospective, controlled study. Phytomedicine 2010 Jun 23. [E-pub ahead of print]

5. Cesarone MR, Belcaro G, Rohdewald P, et al. Comparison of Pycnogenol and Daflon in treating chronic venous insufficiency: a prospective, controlled study. Clin Appl Thromb Hemost 2006;12:205-12.

6. Koch R. Comparative study of Venostasin and Pycnogenol in chronic venous insufficiency. Phytother Res 2002;16:S1-5.

7. Riccioni C, Sarcinella R, Izzo A, et al. Effectiveness of Troxerutin in association with Pycnogenol in the pharmacological treatment of venous insufficiency. Minerva Cardioangiol 2004;52:43-8 [in Italian].

Edema
Dose: 150 mg per day for chronic edema In a controlled study, 150 mg per day of Pycnogenol reduced a measurement of fluid leakage into the tissues of people being treated for hypertension who had swelling of the ankles and feet.1 In another controlled study, ankle swelling during long plane flights was reduced when people followed a regimen of 200 mg of Pycnogenol two to three hours before the flight, 200 mg six hours later, and 100 mg on the following day.2
References

1. Belcaro G, Cesarone MR, Ricci A, et al. Control of edema in hypertensive subjects treated with calcium antagonist (nifedipine) or angiotensin-converting enzyme inhibitors with Pycnogenol. Clin Appl Thromb Hemost 2006;12:440-4.

2. Cesarone MR, Belcaro G, Rohdewald P, et al. Prevention of edema in long flights with Pycnogenol. Clin Appl Thromb Hemost 2005;11:289-94.

Venous Thrombosis
Dose: For plane travel: 200 mg two to three hours before a flight, 200 mg six hours later, and 100 mg on the following day In a controlled study, people at risk for venous thrombosis during plane travel were shown a video explaining in-flight exercises to prevent venous thrombosis and also followed a regimen of 200 mg of pycnogenol two to three hours before the flight, 200 mg six hours later, and 100 mg on the following day.1 Compared with a similar group who only viewed the video, the group taking pycnogenol experienced fewer episodes of venous thrombosis.
References

1. Belcaro G, Cesarone MR, Rohdewald P, et al. Prevention of venous thrombosis and thrombophlebitis in long-haul flights with pycnogenol. Clin Appl Thromb Hemost 2004;10:373-7.

High Cholesterol
Dose: 150 mg per day A preliminary study reported that 150 mg per day of Pycnogenol lowered LDL cholesterol and raised HDL cholesterol in two-thirds of a group of people with normal cholesterol levels.1 Double-blind research is needed to confirm these findings.
References

1. Devaraj S, Vega-Lopez S, Kaul N, et al. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids 2002;37:931-4.

Retinopathy
Dose: 120 to 150 mg per day Preliminary and double blind studies have shown that Pycnogenol slows the progression of retinopathy and improves vision when given in typical amounts of 120 to 150 mg per day.
Type 2 Diabetes
Dose: 100 to 150 mg per day

Preliminary research has suggested that Pycnogenol might help lower blood sugar in people with type 2 diabetes.1 Double-blind trials have shown that 100 to 125 mg per day of Pycnogenol lowers blood sugar in people with type 2 diabetes, but improvement in measures of long-term blood sugar control has not been consistent.2, 3

Preliminary and double-blind studies have also shown Pycnogenol (typically 120 to 150 mg per day) slows the progression of diabetic retinopathy and improves vision.4, 5, 6, 7 In a controlled trial of diabetic patients with symptoms of damage to the small blood vessels of the lower legs and feet, 150 mg per day of Pycnogenol improved measures of skin health and blood flow to the feet.8 In another controlled study, diabetic skin ulcers were treated with standard medications plus either 150 mg per day of Pycnogenol orally, 100 mg pycnogenol topically applied to the ulcers, or a combination of oral and topical Pycnogenol treatment.9 All treatments produced complete healing in more subjects after six weeks compared with a control group receiving no Pycnogenol treatment, but the group receiving oral and topical Pycnogenol had the greatest reductions in ulcer size and in pain and other associated symptoms.

References

1. Liu X, Zhou HJ, Rohdewald P. French maritime pine bark extract Pycnogenol dose-dependently lowers glucose in type 2 diabetic patients. Diabetes Care 2004;27:839 [letter].

2. Liu X, Wei J, Tan F, et al. Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type II. Life Sci 2004;75:2505-13.

3. Zibadi S, Rohdewald PJ, Park D, Watson RR. Reduction of cardiovascular risk factors in subjects with type 2 diabetes by Pycnogenol supplementation. Nutr Res 2008;28:315-20.

4. Schonlau F, Rohdewald P. Pycnogenol for diabetic retinopathy. A review. Int Ophthalmol 2001;24:161-71 [review].

5. Schonlau F, Rohdewald P. Pycnogenol for diabetic retinopathy. A review. Int Ophthalmol 2001;24:161-71 [review].

6. Spadea L, Balestrazzi E. Treatment of vascular retinopathies with Pycnogenol. Phytother Res 2001;15:219-23.

7. Steigerwalt R, Belcaro G, Cesarone MR, et al. Pycnogenol improves microcirculation, retinal edema, and visual acuity in early diabetic retinopathy. J Ocul Pharmacol Ther 2009;25:537-40.

8. Cesarone MR, Belcaro G, Rohdewald P, et al. Improvement of diabetic microangiopathy with pycnogenol: A prospective, controlled study. Angiology 2006;57:431-6.

9. Belcaro G, Cesarone MR, Errichi BM, et al. Diabetic ulcers: microcirculatory improvement and faster healing with pycnogenol. Clin Appl Thromb Hemost 2006;12:318-23.

Type 1 Diabetes, Diabetic Retinopathy, and Skin Ulcers
Dose: Refer to label instructions
Dysmenorrhea
Dose: 60 mg per day Preliminary research reported that 60 mg Pycnogenol twice daily for two months reduced abdominal and back pain during menses.1 A double blind trial by the same researchers using 60 mg Pycnogenol per day confirmed these findings for women with more severe pain, but not for those whose menstrual pain was mild.2
References

1. Kohama T, Suzuki N, Ohno S, Inoue M. Analgesic efficacy of French maritime pine bark extract in dysmenorrhea: an open clinical trial. J Reprod Med 2004;49:828-32.

2. Suzuki N, Uebaba K, Kohama T, et al. French maritime pine bark extract significantly lowers the requirement for analgesic medication in dysmenorrhea: a multicenter, randomized, double-blind, placebo-controlled study. J Reprod Med 2008;53:338-46.

Menopause
Dose: 60 to 200 mg per day In a double-blind trial, perimenopausal women who took 200 mg per day of Pycnogenol experienced reduction of menopausal symptoms as measured by a women's health questionnaire.1 Improvement in menopausal symptoms was also reported in another double-blind trial, in which women took 30 mg of pycnogenol twice a day for three months.2
References

1. Yang HM, Liao MF, Zhu SY, et al. A randomised, double-blind, placebo-controlled trial on the effect of Pycnogenol on the climacteric syndrome in peri-menopausal women. Acta Obstet Gynecol Scand 2007;86:978-85.

2. Kohama T, Negami M. Effect of low-dose French maritime pine bark extract on climacteric syndrome in 170 perimenopausal women: a randomized, double-blind, placebo-controlled trial. J Reprod Med 2013;58:39-46.

Endometriosis
Dose: 60 mg per day

In a preliminary study,1 symptoms of endometriosis gradually declined when women took 60 mg per day of Pycnogenol, which is high in flavonoids. Double-blind research is needed to confirm these findings.

References

1. Kohama T, Herai K, Inoue M. Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. J Reprod Med 2007;52:703-8.

Pregnancy and Postpartum Support
Dose: 30 mg per day In a controlled study, pregnant women who took 30 mg per day of Pycnogenol reported some relief of pain in the legs, pelvis, hip, and low back.1 Double-blind research is needed to confirm these findings.
References

1. Kohama T, Inoue M. Pycnogenol alleviates pain associated with pregnancy. Phytother Res 2006;20:232-4.

Erectile Dysfunction
Dose: 120 mg daily

In a double-blind study of men with erectile dysfunction, supplementing with 120 mg per day of Pycnogenol improved erectile function, whereas placebo treatment had no effect.1

References

1. Durackova Z, Trebaticky B, Novotny V, et al. Lipid metabolism and erectile function improvement by Pycnogenol(R), extract from the bark of Pinus pinaster in patients suffering from erectile dysfunction-a pilot study. Nutr Res 2003;23:1189-98.

Male Infertility
Dose: Refer to label instructions
Dysmenorrhea
Dose: 60 mg per day Preliminary research reported that 60 mg Pycnogenol twice daily for two months reduced abdominal and back pain during menses.1 A double blind trial by the same researchers using 60 mg Pycnogenol per day confirmed these findings for women with more severe pain, but not for those whose menstrual pain was mild.2
References

1. Kohama T, Suzuki N, Ohno S, Inoue M. Analgesic efficacy of French maritime pine bark extract in dysmenorrhea: an open clinical trial. J Reprod Med 2004;49:828-32.

2. Suzuki N, Uebaba K, Kohama T, et al. French maritime pine bark extract significantly lowers the requirement for analgesic medication in dysmenorrhea: a multicenter, randomized, double-blind, placebo-controlled study. J Reprod Med 2008;53:338-46.

Endometriosis
Dose: 60 mg per day

In a preliminary study,1 symptoms of endometriosis gradually declined when women took 60 mg per day of Pycnogenol, which is high in flavonoids. Double-blind research is needed to confirm these findings.

References

1. Kohama T, Herai K, Inoue M. Effect of French maritime pine bark extract on endometriosis as compared with leuprorelin acetate. J Reprod Med 2007;52:703-8.

Sunburn
Dose: 1.1 to 1.66 mg per 2.2 lbs (1 kg) of body weight per day during periods of high sun exposure

Proanthocyanidins (OPCs) are a group of flavonoids found in pine bark, grape seed, and other plant sources. In a preliminary trial, volunteers were supplemented with Pycnogenol, an extract of French maritime pine bark rich in OPCs, in the amount of 1.1 mg per 2.2 pounds of body weight per day for the first four weeks, and 1.66 mg per 2.2 pounds of body weight per day for the next four weeks.1 Compared with ultraviolet sensitivity before supplementation, the lower amount of Pycnogenol was found to significantly increase the amount of ultraviolet rays necessary to cause sunburn, and the higher amount was significantly more effective than the lower amount.

References

1. Saliou C, Rimbach G, Moini H, et al. Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-B-dependent gene expression in keratinocytes are modulated by a French maritime pine bark extract. Free Radic Biol Med 2001;30:154-60.

Skin Ulcers
Dose: 150 mg per day orally, along with topical application of 100 mg daily In a controlled study, diabetic skin ulcers were treated with standard medications plus either 150 mg per day of Pycnogenol orally, 100 mg Pycnogenol topically applied to the ulcers daily, or a combination of oral and topical Pycnogenol treatment.1 All treatments produced complete healing in more subjects after six weeks compared with a control group receiving no Pycnogenol treatment, but the group receiving oral and topical Pycnogenol had the greatest reductions in ulcer size and in pain and other associated symptoms. In a small controlled study of venous skin ulcers, the same combination of oral and topical Pycnogenol was more effective for healing than oral Pycnogenol treatment alone.2
References

1. Belcaro G, Cesarone MR, Errichi BM, et al. Diabetic ulcers: microcirculatory improvement and faster healing with pycnogenol. Clin Appl Thromb Hemost 2006;12:318-23.

2. Belcaro G, Cesarone MR, Errichi BM, et al. Venous ulcers: microcirculatory improvement and faster healing with local use of Pycnogenol. Angiology 2005;56:699-705.

Melasma
Dose: 75 mg per day Melasma is a disorder of increased skin pigmentation. In a preliminary study, 80% of women with melasma who took 75 mg per day of Pycnogenol experienced lightening and shrinking of the pigmented area of the skin.1 More research is needed to evaluate Pycnogenol for this condition.
References

1. Ni Z, Mu Y, Gulati O. Treatment of melasma with Pycnogenol. Phytother Res 2002;16:567-71.

Attention Deficit-Hyperactivity Disorder
Dose: 1 mg daily per 2.2 pounds body weight daily A double-blind study in Slovakia reported that 1 mg daily per 2.2 pounds body weight of Pycnogenol reduced symptoms of hyperactivity and improved attention, coordination, and concentration after one month in a group of children with ADHD.1 However, a double-blind study in adults with ADHD did not find 1 mg Pycnogenol per pound of body weight daily was effective for ADHD symptoms.2
References

1. Trebaticka J, Kopasova S, Hradecna Z, et al. Treatment of ADHD with French maritime pine bark extract, Pycnogenol. Eur Child Adolesc Psychiatry 2006;15:329-35.

2. Tenenbaum S, Paull JC, Sparrow EP, et al. An experimental comparison of Pycnogenol and methylphenidate in adults with Attention-Deficit/Hyperactivity Disorder (ADHD). J Atten Disord 2002;6:49-60.

Osteoarthritis
Dose: 100 to 150 mg per day

In a double-blind trial, 100 mg per day of Pycnogenol reduced pain and other osteoarthritis symptoms, improved walking performance, and reduced the use of pain-relieving medication.1 Another double blind trial found that 150 mg per day also improved symptoms and reduced use of pain-relieving medication.2

References

1. Belcaro G, Cesarone MR, Errichi S, et al. Treatment of osteoarthritis with Pycnogenol. The SVOS (San Valentino Osteo-arthrosis Study). Evaluation of signs, symptoms, physical performance and vascular aspects. Phytother Res 2008;22:518-23.

2. Cisar P, Jany R, Waczulikova I, et al. Effect of pine bark extract (Pycnogenol) on symptoms of knee osteoarthritis. Phytother Res 2008;22:1087-92.

Menopause
Dose: 60 to 200 mg per day In a double-blind trial, perimenopausal women who took 200 mg per day of Pycnogenol experienced reduction of menopausal symptoms as measured by a women's health questionnaire.1 Improvement in menopausal symptoms was also reported in another double-blind trial, in which women took 30 mg of pycnogenol twice a day for three months.2
References

1. Yang HM, Liao MF, Zhu SY, et al. A randomised, double-blind, placebo-controlled trial on the effect of Pycnogenol on the climacteric syndrome in peri-menopausal women. Acta Obstet Gynecol Scand 2007;86:978-85.

2. Kohama T, Negami M. Effect of low-dose French maritime pine bark extract on climacteric syndrome in 170 perimenopausal women: a randomized, double-blind, placebo-controlled trial. J Reprod Med 2013;58:39-46.

Asthma
Dose: 1 mg per pound of body weight per day, in two divided dosesIn a double-blind trial, supplementing with Pycnogenol significantly improved lung function and asthma symptoms and significantly reduced the need for rescue medication in a group of children (ages 6 to 18 years) with asthma.1 In contrast, no significant changes were seen in the placebo group. The amount of Pycnogenol used was 1 mg per pound of body weight per day, in two divided doses, for three months.
References

1. Lau BH, Riesen SK, Truong KP, et al. Pycnogenol as an adjunct in the management of childhood asthma. J Asthma 2004;41:825-32.

Gingivitis
Dose: 6 pieces chewing gum per day containing 5 mg each In a double blind trial, people with gingivitis chewed six pieces daily of a gum, each containing 5 mg Pycnogenol.1 While a group chewing gum without pycnogenol experienced continued gum bleeding and plaque formation after 14 days, the pycnogenol group had less gum bleeding and no additional plaque formation.
References

1. Kimbrough C, Chun M, dela Roca G, Lau BH. PYCNOGENOL chewing gum minimizes gingival bleeding and plaque formation. Phytomedicine 2002;9:410-3.

Hemorrhoids
Dose: 300 mg per day for four days followed by 150 mg per day for three days, with or without daily use of a 0.5% topical cream at the same time In a controlled trial,1 people with acute hemorrhoids were treated either with oral Pycnogenol (300 mg per day for four days followed by 150 mg per day for three days), an oral placebo, oral Pycnogenol plus daily use of a topical 0.5% Pycnogenol cream, or oral Pycnogenol plus daily use of a placebo cream. All groups receiving either or both forms of Pycnogenol had greater reduction in signs and symptoms in 7 to 14 days, and fewer recurrences over the following month than the oral placebo group. The combination treatment appeared somewhat more effective than oral Pycnogenol alone, but whether this difference was statistically significant is unclear.
References

1. Belcaro G, Cesarone MR, Errichi B, et al. Pycnogenol treatment of acute hemorrhoidal episodes. Phytother Res 2010;24:438-44.

Erectile Dysfunction
Dose: 120 mg daily

In a double-blind study of men with erectile dysfunction, supplementing with 120 mg per day of Pycnogenol improved erectile function, whereas placebo treatment had no effect.1

References

1. Durackova Z, Trebaticky B, Novotny V, et al. Lipid metabolism and erectile function improvement by Pycnogenol(R), extract from the bark of Pinus pinaster in patients suffering from erectile dysfunction-a pilot study. Nutr Res 2003;23:1189-98.

Age-Related Cognitive Decline
Dose: 150 mg per day A double-blind study of healthy senior people reported that 150 mg per day of Pycnogenol improved some measures of memory after three months, compared with a group taking a placebo.1
References

1. Ryan J, Croft K, Mori T, et al. An examination of the effects of the antioxidant Pycnogenol on cognitive performance, serum lipid profile, endocrinological and oxidative stress biomarkers in an elderly population. J Psychopharmacol 2008;22:553-62.

Age-Related Cognitive Decline
Dose: 150 mg per day A double-blind study of healthy senior people reported that 150 mg per day of Pycnogenol improved some measures of memory after three months, compared with a group taking a placebo.1
References

1. Ryan J, Croft K, Mori T, et al. An examination of the effects of the antioxidant Pycnogenol on cognitive performance, serum lipid profile, endocrinological and oxidative stress biomarkers in an elderly population. J Psychopharmacol 2008;22:553-62.

Pregnancy and Postpartum Support
Dose: 30 mg per day In a controlled study, pregnant women who took 30 mg per day of Pycnogenol reported some relief of pain in the legs, pelvis, hip, and low back.1 Double-blind research is needed to confirm these findings.
References

1. Kohama T, Inoue M. Pycnogenol alleviates pain associated with pregnancy. Phytother Res 2006;20:232-4.

Jet Lag
Dose: 150 mg per day for seven days, beginning two days before travel In controlled studies, 150 mg of Pycnogenol was taken for two days before and five days after air travel.1 Jet lag symptoms were milder and lasted for a shorter period of time compared with untreated control groups.
References

1. Belcaro G, Cesarone MR, Steigerwalt RJ, et al. Jet-lag: prevention with Pycnogenol. Preliminary report: evaluation in healthy individuals and in hypertensive patients. Minerva Cardioangiol 2008;56(5 Suppl):3-9.

Leg Cramps
Dose: Refer to label instructionsA preliminary study of people experiencing at least four episodes per week of leg cramps due to either athletic activity, circulatory disorders, or unknown causes reported that 200 mg per day of Pycnogenol significantly reduced episodes of leg cramps.1 Double-blind research is needed to further explore this use of Pycnogenol.
References

1. Vinciguerra G, Belcaro G, Cesarone MR, et al. Cramps and muscular pain: prevention with pycnogenol in normal subjects, venous patients, athletes, claudicants and in diabetic microangiopathy. Angiology 2006;57:331-9.

Lupus
Dose: 60 to 120 mg per day

In a small, controlled study, people with SLE were given medication and either a placebo or Pycnogenol in the amount of 120 mg per day for 30 days followed by 60 mg per day for another 30 days. SLE disease activity, measured with a combination of signs, symptoms, and blood measurements, declined further in the group taking Pycnogenol.1

References

1. Stefanescu M, Matache C, Onu A, et al. Pycnogenol efficacy in the treatment of systemic lupus erythematosus patients. Phytother Res 2001;15:698-704.

Pycnogenol is an extract of the bark of the French maritime pine, which grows along the Atlantic coast of southwestern France.

Copyright 2014 Aisle7. All rights reserved. Aisle7.com

The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2015.

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Ratings and Reviews

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GRANDPA BRANDS 1010469Grandpa Brand Pine Tar Soap
 
5.0

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100%

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  • Lathers well (3)

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    • Shower (3)
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    Reviewed by 5 customers

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    (1 of 1 customers found this review helpful)

     
    5.0

    Helps incredibly with Eczema .

    By dmccain

    from Franklin, IN.

    About Me Brand Buyer

    Pros

    • Lathers Well

    Cons

      Best Uses

      • Baths
      • Showers

      Comments about GRANDPA BRANDS 1010469 Grandpa Brand Pine Tar Soap:

      I have eczema and it helps in many ways .I do not use any prescription creams ,I just bathe with this soap daily sometimes twice a day if it is flaring up.

      (1 of 1 customers found this review helpful)

       
      5.0

      smells funny but works

      By lauramiller

      from fairfield, ia

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      Pros

      • Cleans Effectively
      • Lathers Well

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        • Showers

        Comments about GRANDPA BRANDS 1010469 Grandpa Brand Pine Tar Soap:

        Really helps with skin allergies especially poison ivy contact.

        (1 of 2 customers found this review helpful)

         
        5.0

        "I will buy this product again!"

        By jose.guillen

        from Hesperia, Ca

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        Pros

        • Cleans Effectively
        • Lathers Well
        • Moisturizing
        • Pleasant Smell

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          • Baths
          • Facial Soap
          • Hand Soap
          • Showers

          Comments about GRANDPA BRANDS 1010469 Grandpa Brand Pine Tar Soap:

          I use this product once a day
          --in the evening before going to sleep.

          (2 of 2 customers found this review helpful)

           
          5.0

          Old Fashioned Soap

          By marlonsmith

          from Mobile, Al

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          • Fragrant
          • Soothing

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            • Daily Use

            Comments about GRANDPA BRANDS 1010469 Grandpa Brand Pine Tar Soap:

            Can also be used on the hair about once a week.

            (2 of 3 customers found this review helpful)

             
            5.0

            GREAT FOR MY PETS

            By Agusi48

            from Naples Florida

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            Pros

            • Effective
            • Fragrant
            • Simple to Use
            • Soothing

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              • Daily Use

              Comments about GRANDPA BRANDS 1010469 Grandpa Brand Pine Tar Soap:

              I USE IT TO BATH MY DOGS.KEEPS THEM FROM THAT DIRTY DOGGIE SMELL.WORKS VERY WELL.AND MOST OF ALL THEY SEEM TO ENJOT IT

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