As a dietary supplement, take 2 level teaspoons daily, prior to exercise. Serious athletes may want to double the dosage during training.
|Serving Size 2 teaspoon(s)|
|Servings Per Container 22|
|Amount Per Serving||% DV|
|Total Carbohydrate||5.00 g||2%|
|D-Ribose Powder (Bioenergy RIBOSE™)||5000.00 mg||**|
|** Daily Value (DV) not established|
No Egg, No Gluten, No Milk, No Salt, No Shellfish, No Soy, No Starch, No Wheat, No Yeast
Storage Instructions: Store in a cool, dry place.
Warning: Do not eat Freshness Packet Enclosed.
In a controlled study, men with severe coronary heart disease were given an exercise test, after which they took either 15 grams of ribose or a placebo four times daily for three days. Compared with the initial test, men taking ribose were able to exercise significantly longer before experiencing chest pain and before abnormalities appeared on their electrocardiogram (ECG), but only the ECG changes were significantly improved compared with those in the placebo group.1 Sports supplement manufacturers recommend 1 to 10 grams per day of ribose, while heart disease patients and people with rare enzyme deficiencies have been given up to 60 grams per day.
Ribose is a type of sugar used by the body to make the energy-containing substance adenosine triphosphate (ATP). Intense exercise depletes muscle cells of ATP as well as the ATP precursors made from ribose,1, 2 though these deficits are typically replaced within minutes.3 Unpublished reports suggested that ribose supplementation might increase power during short, intense bouts of exercise.4, 5 However, in a double-blind study, exercisers took four grams of ribose four times per day during a six-day strength-training regimen, and no effects on muscle power or ATP recovery in exercised muscles were found.6 In two other controlled studies, either 10 grams of ribose per day for five days or 8 grams every 12 hours for 36 hours resulted in only minor improvements in some measures of performance during repetitive sprint cycling.7, 8
1. Hellsten-Westing,Y, Norman B, Balsom PD, Sjodin B. Decreased resting levels of adenine nucleotides in human skeletal muscle after high-intensity training. J Appl Physiol 1993;74:2523-8.
2. Tullson PC, Terjung RL. Adenine nucleotide synthesis in exercising and endurance-trained skeletal muscle. Am J Physiol 1991;261:C342-7.
3. Zhao S, Snow RJ, Stathis CG, et al. Muscle adenine nucleotide metabolism during and in recovery from maximal exercise in humans. J Appl Physiol 2000;88:1513-9.
4. Ziegenfuss T. The effects of Ribocell supplementation on repeated sprint performance: a pilot study. Submitted to the American College of Sports Medicine 47th Annual Meeting, 1999.
5. Trappe S. Effect of ribose supplementation on nucleotide depletion following high intensity exercise in human skeletal muscle, 1999. Data on file at Bioenergy, Inc., 13840 Johnson St. N.E., Minneapolis, MN 55304.
6. Op 'T Eijnde B, Van Leemputte M, Brouns F, et al. No effects of oral ribose supplementation on repeated maximal exercise and de novo ATP resynthesis. J Appl Physiol 2001;91:2275-81.
7. Kreider RB, Melton C, Greenwood M, et al. Effects of oral D-ribose supplementation on anaerobic capacity and selected metabolic markers in healthy males. Int J Sport Nutr Exerc Metab 2003;13:76-86.
8. Berardi JM, Ziegenfuss TN. Effects of ribose supplementation on repeated sprint performance in men. J Strength Cond Res 2003;17:47-52.
Ribose is a type of sugar normally made in the body from glucose. Ribose plays important roles in the synthesis of RNA, DNA, and the energy-containing substance adenosine triphosphate (ATP).
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