{"id":11459,"date":"2022-08-20T09:54:10","date_gmt":"2022-08-20T14:54:10","guid":{"rendered":"https:\/\/gncholdings.wpengine.com\/learn\/beauty\/gnc-product-series-a-deep-dive-into-total-lean-lean-shake-25-rtd\/"},"modified":"2026-01-30T13:43:08","modified_gmt":"2026-01-30T18:43:08","slug":"deep-dive-into-total-lean-lean-shake-25-rtd","status":"publish","type":"post","link":"https:\/\/www.gnc.com\/learn\/diet\/deep-dive-into-total-lean-lean-shake-25-rtd.html","title":{"rendered":"GNC Product Series: A Deep Dive Into Total Lean Lean Shake\u2122 25 RTD"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"11459\" class=\"elementor elementor-11459\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-686c7fef elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"686c7fef\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1734cdb6\" data-id=\"1734cdb6\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-353ed1e8 elementor-widget elementor-widget-text-editor\" data-id=\"353ed1e8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.21.0 - 30-04-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p><span style=\"color: #222931; font-family: proxima-nova-extra-condensed-bold, sans-serif; font-size: 48px; font-style: inherit; font-weight: bold; text-transform: uppercase;\">What did GNC Study?<\/span><\/p><section class=\"container simple-block-content topMag-70 topMag-sm-40 botMag-20 botMag-sm-40 botMag-md-40\" data-cmsmodule=\"text\" data-cmsslot=\"article-cms-content\"><div><p>At GNC, research informs everything we do \u2013 so you get the real results you\u2019re looking for. What most people don\u2019t know is that GNC has invested in clinical research on several of its top-selling products to demonstrate their effectiveness.<\/p><p>In this article, we\u2019ll do a deep dive into one of GNC\u2019s clinical studies where a <a title=\"ready-to-drink meal replacement\" href=\"https:\/\/www.gnc.com\/gnc-total-lean\/total-lean-ready-to-drink\/\" target=\"_blank\" rel=\"noopener\">ready-to-drink meal replacement<\/a> was put to the test. Total Lean\u00ae Lean Shake\u2122 25 Ready-To-Drink contains 25 g of protein, plus more than 20 essential vitamins and minerals you would find in a typical meal! Passionate about the health and wellness of their customers, GNC\u2019s researchers were interested in learning the impact their meal replacement formula would have on body weight, when used as part of a weight loss journey.<\/p><\/div><\/section><section class=\"container simple-block-content topMag-70 topMag-sm-40 botMag-20 botMag-sm-40 botMag-md-40\" data-cmsmodule=\"text\" data-cmsslot=\"article-cms-content\"><div><h3 class=\"subheading\" style=\"color: #222931;\">What Was The Objective of The Study?<\/h3><p>The primary goal of this study was to determine the effectiveness of <a title=\"GNC\u2019s Total Lean\u00ae\" href=\"https:\/\/www.gnc.com\/gnc-total-lean\/\" target=\"_blank\" rel=\"noopener\">GNC\u2019s Total Lean\u00ae<\/a> Lean Shake\u2122 25 formula on body weight. Secondary objectives of the study were to evaluate the effects on body composition, including body fat, waist and hip circumference, and blood lipid levels. Researchers believed their meal replacement formula would aid in the loss of body fat while preserving lean muscle.<\/p><\/div><\/section><section class=\"container simple-block-content topMag-70 topMag-sm-40 botMag-20 botMag-sm-40 botMag-md-40\" data-cmsmodule=\"text\" data-cmsslot=\"article-cms-content\"><div><h3 class=\"subheading\" style=\"color: #222931;\">Who Were The Study Participants?<\/h3><p>109 overweight and obese males and females between 21 and 55 years of age. Volunteers had a Body Mass Index (BMI) of no less than 25 and no greater than 39.9.<\/p><\/div><\/section><section class=\"container simple-block-content topMag-70 topMag-sm-40 botMag-20 botMag-sm-40 botMag-md-40\" data-cmsmodule=\"text\" data-cmsslot=\"article-cms-content\"><div><h3 class=\"subheading\" style=\"color: #222931;\">What Was The Study Design?<\/h3><p>GNC chose a randomized, controlled, parallel group study. Volunteers in both groups followed a 1500 calorie per day meal plan and were randomly assigned to one of two groups:<\/p><ul><li><b>Group 1<\/b>: Received two Total Lean\u00ae Lean Shake\u2122 25 meal replacements daily in place of breakfast and lunch. They were encouraged to consume a healthy dinner that fit into their meal plan.<\/li><li><b>Group 2<\/b>: Did not receive a meal replacement<\/li><\/ul><p>Participants were instructed to walk for a minimum of 30 minutes at least three times per week. Vital signs, height, weight, body composition, blood chemistry and lipid profiles were collected at six points throughout the duration of the 12-week study.<\/p><\/div><\/section><section class=\"container simple-block-content topMag-70 topMag-sm-40 botMag-20 botMag-sm-40 botMag-md-40\" data-cmsmodule=\"text\" data-cmsslot=\"article-cms-content\"><div><h3 class=\"subheading\" style=\"color: #222931;\">What were the results of the study?<\/h3><p>Researchers found that over a period of 12 weeks, the group receiving the Total Lean Shake\u00ae formula <b>lost nearly 2 times the weight<\/b> (-7.6 lbs) when compared to the group following the 1500 calorie diet alone (-3.9 lbs). The meal replacement group also saw a <b>larger reduction in body mass index<\/b> (-1.2 km\/m2) vs diet alone (0.6 km\/m2).<\/p><\/div><\/section><section class=\"container simple-block-content topMag-70 topMag-sm-40 botMag-20 botMag-sm-40 botMag-md-40\" data-cmsmodule=\"text\" data-cmsslot=\"article-cms-content\"><div><h3 class=\"subheading\" style=\"color: #222931;\">What does this mean?<\/h3><p>As revolutionaries in the field, GNC put it\u2019s ready-to-drink meal replacement formula to the test, something competitors rarely do. The results of this study mean that not only is Lean Shake 25TM RTD delicious and packed with high quality protein, but when used as part of healthy diet and exercise regimen, it can help you lose more weight than just trying to cut calories alone.<\/p><\/div><\/section><section class=\"container simple-block-content topMag-70 topMag-sm-40 botMag-20 botMag-sm-40 botMag-md-40\" data-cmsmodule=\"text\" data-cmsslot=\"article-cms-content\"><div><h3 class=\"subheading\" style=\"color: #222931;\">Where To Buy Total Lean\u00ae Shake\u2122 RTD?<\/h3><p>Explore how to use GNC Total Lean Shake for weight loss and support your wellness journey with Total Lean\u00ae Shake\u2122 RTD in a variety of flavors and added benefits:<\/p><ul><li><a title=\"GNC Total Lean\u00ae Lean Shake\u2122 25 RTD\" href=\"https:\/\/www.gnc.com\/protein-drinks\/GNCTotalLeanLeanShake12Pack.html\" target=\"_blank\" rel=\"noopener\">GNC Total Lean\u00ae Lean Shake\u2122 25 RTD<\/a><\/li><li><a title=\"GNC Total Lean\u00ae Lean Shake\u2122 Burn RTD\" href=\"https:\/\/www.gnc.com\/ready-to-drink-protein\/333036.html\" target=\"_blank\" rel=\"noopener\">GNC Total Lean\u00ae Lean Shake\u2122 Burn RTD<\/a><\/li><\/ul><\/div><\/section><section class=\"container simple-block-content topMag-70 topMag-sm-40 botMag-20 botMag-sm-40 botMag-md-40\" data-cmsmodule=\"text\" data-cmsslot=\"article-cms-content\"><div><h6 class=\"h6\"><i>^A randomized clinical study consisting of 109 healthy participants compared the use of Lean Shake 25 Ready-to-Drink in conjunction with a meal and exercise plan (total daily caloric intake of 1500 calories) to a 1500 calorie diet &amp; exercise plan alone. This study resulted in nearly twice as much total weight loss (-7.6 vs. -3.9 pounds), along with improvements in Body Mass Index (BMI) among the Lean Shake 25 RTD users at the end of 12 weeks. Meal &amp; exercise plan available at <b><a title=\"www.totallean.com\" href=\"https:\/\/www.gnc.com\/live-total-lean.html\" target=\"_blank\" rel=\"noopener\">https:\/\/www.gnc.com\/live-total-lean.html<\/a>.<\/b><\/i><\/h6><\/div><\/section><p><!-- CMS-content-main-END --><br \/><!-- CMS-ADD-CONTENT-START --><br \/><!-- CMS-ADD-CONTENT-END --><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Read the GNC product series as we look at Total Lean\u00ae Lean Shake\u2122 25 RTD. Get the science and benefits behind this protein shake brand. Order online today!<\/p>\n","protected":false},"author":16,"featured_media":20571,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[2159,1153],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A Deep Dive Into Total Lean\u00ae Lean Shake\u2122 25 RTD | GNC<\/title>\n<meta name=\"description\" content=\"Read the GNC product series as we look at Total Lean Lean Shake\u2122 25 RTD. 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