{"id":11511,"date":"2022-01-17T08:22:47","date_gmt":"2022-01-17T13:22:47","guid":{"rendered":"https:\/\/gncholdings.wpengine.com\/learn\/beauty\/how-do-arginine-citrulline-produce-nitric-oxide\/"},"modified":"2025-05-29T04:41:06","modified_gmt":"2025-05-29T09:41:06","slug":"how-do-arginine-and-citrulline-produce-nitric-oxide","status":"publish","type":"post","link":"https:\/\/www.gnc.com\/learn\/fitness\/how-do-arginine-and-citrulline-produce-nitric-oxide.html","title":{"rendered":"How Do Arginine + Citrulline Produce Nitric Oxide?"},"content":{"rendered":"<h2>HOW DO ARGININE &amp; CITRULLINE PRODUCE NITRIC OXIDE?<\/h2>\n<p>If you\u2019ve ever taken a pre-workout, chances are you\u2019ve heard of arginine, citrulline or sodium nitrate. One or all of these ingredients are commonly featured in formulas that claim to increase <a href=\"\/muscle-builders\/nitric-oxide\/\">nitric oxide<\/a> production and boost performance. But how does this actually work? Read on to learn how these ingredients make it happen and what it means for you and your workout.<\/p>\n<p><strong>Related Reading<\/strong>: <a href=\"https:\/\/www.gnc.com\/learn\/fitness\/workout-powerhouse-no-boosters.html\">A WORKOUT POWERHOUSE: NO BOOSTERS<\/a><\/p>\n<h2>WHAT DOES NITRIC OXIDE DO?<\/h2>\n<p>Nitric oxide is a vasodilator, meaning it improves blood flow by prompting blood vessels to open wider. Healthier blood flow means more oxygen and nutrients are delivered to your muscles, which is especially important during exercise. Supplements don\u2019t contain nitric oxide itself, but rather substances that your body uses to produce it. Those substances are arginine, citrulline and nitrates.<\/p>\n<h3>ARGININE<\/h3>\n<p>Arginine is a key amino acid and a building block in the production of nitric oxide. Your body uses a metabolic pathway to convert arginine into nitric oxide. <a href=\"https:\/\/www.gnc.com\/amino-acids\/l-arginine\/\">Arginine supplements<\/a> fuels nitric oxide production, which in turn enhances blood flow and helps maintain your blood vessel tone.<\/p>\n<h3>CITRULLINE<\/h3>\n<p>Like arginine, citrulline is an amino acid. <a href=\"https:\/\/www.gnc.com\/pre-workout-supplements\/citrulline\/\">Citrulline supplements<\/a> can be recycled to arginine via the citrulline-N.O. cycle and works with arginine to help fuel muscle cells and support your body\u2019s production of nitric oxide.<\/p>\n<h3>NITRATES<\/h3>\n<p>Nitrates, found in certain foods or as a dietary supplement, can also be converted to nitric oxide, especially during times of decreased oxygen availability (think high-intensity exercise). They also have the potential to assist in oxygen delivery to working muscles. Certain vegetables, such as spinach, <a href=\"\/superfoods\/beets\/\">beet root<\/a> and celery, have high concentrations of nitrate. Because soil concentrations vary, however, it\u2019s difficult to determine just how much you will get from these vegetables. Now that you\u2019re an expert on nitric oxide and its building blocks, look for them in your pre-workouts!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Find out how arginine, citrulline and nitrates support nitrix oxide production &#8211; helping you boost your workout and build muscle.<\/p>\n","protected":false},"author":27,"featured_media":14777,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"footnotes":""},"categories":[2164,1271],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How Do Arginine + 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