5-HTP 100mg Time Release | GNC
Sugar Free Sugar Free
Dairy Free Dairy Free
Egg Free Egg Free
Soy Free Soy Free
No Artificial Flavors/Colors No Artificial Flavors/Colors
Corn Free Corn Free
No Preservatives No Preservatives
View All Specialty Diets
Sugar Free Sugar Free
Dairy Free Dairy Free
Egg Free Egg Free
Soy Free Soy Free
No Artificial Flavors/Colors No Artificial Flavors/Colors
Corn Free Corn Free
No Preservatives No Preservatives
View All Specialty Diets
Note: This product cannot be sold in Canada

Product Information



  • Promotes Positive Mood
  • Helps Control Appetite

    Natrol® 5-HTP TR 100mg Time Release is a drug-free plantderived source of an amino acid that naturally increases the body’s level of serotonin, the chemical messenger that affects emotions, behavior, appetite, thought and sleep. Regular use of Natrol 5-HTP helps provide a more positive outlook, promotes relaxation, calm and greater appetite control. Natrol 5-HTP TR is 100% vegetarian and has a controlled delivery system that releases 5-HTP slowly and then steadily over a period of 12 hours.
  • Ingredients

    Nutrition Facts
    Serving Size  1 Tablet(s)
    Servings Per Container  45

    Amount Per Serving     % DV

    5-HTP (5-Hydroxytryptophan) (derived from Griffonia simplicifolia) (seed)  100 mg   **

    ** Daily Value (DV) not established.
    Other Ingredients
    Cellulose, Dibasic Calcium Phosphate, Hypromellose, Silica, Stearic Acid, Magnesium Stearate, Methylcellulose, Glycerin
    Label (click image to enlarge)

    How To Use

    Take 1 tablet, up to two times daily, with food. Do not exceed recommended dose.
    Keep out of reach of children.
    , Consult your healthcare professional prior to use if you have or suspect a medical condition or are taking prescription drugs including drugs for depression, migraines, Parkinson’s disease or psychiatric disorders. Do not use with other supplements containing L-tryptophan or 5-HTP. Do not use if you are pregnant, lactating or under the age of 18 years.
    Store in a cool, dry place.
    Manufactured by NATROL, Inc. Chatsworth, CA 91311 • USA


    4.4 / 5.0
    10 Reviews
    5 Stars
    4 Stars
    3 Stars
    2 Stars
    1 Star
    Didn’t help
    Had high hopes, but it did nothing
    January 29, 2019
    9 months ago
    Seems to help!
    I get stressed and drained by family life in the evening, so I take this around 4pm with a snack and a multivitamin, and I get through the evening with less stress. I notice the difference of whether I've taken it or not, and how I handle the dinner/bath/bedtime hours. Worth my sanity.
    August 23, 2018
    10 months ago
    Great product
    It seems to really help with my mood. I quit smoking a little over a month ago,and this had been wonderful in assisting me to keep my cool when my house and kids stress me out.
    April 4, 2018
    1 year ago
    Happy with this
    When I first started using 5-htp I was using the straight 100ml extra strength capsules and was having a lot of stomach upset. I have started using the time release kind and what a difference. No more stomach issues. So happy with this product.
    February 4, 2018
    1 year ago
    Definite enhancer to great sleep and relaxed state of mind
    August 6, 2017
    1 year ago
    Great Product! I Feel Alive!!
    I run a sales organization in the US and I make sure all my employees take this. Since they have been taking the pills, they have tripled their numbers in sales and have all lost 10-15 pounds.
    March 18, 2015
    Works great for appetite control
    This product has worked great for me. I thought I would try this to see if it would mellow me out (I tend to worry a lot) and help me lose weight.

    I found that the pills do help to mellow me out more. But, the appetite control is what I love about taking these. I used to eat big lunches and dinners as well as want snack in between.

    After taking these pills I found that if I had a big lunch that I couldn't finish it. I would feel full. I no longer needed snacks in between meals.

    These pills work great for me. I take one in the morning and that is all I need for the rest of the day.
    September 27, 2014
    Works great
    Really helps to uplight my mood throughout the day. Helps me to get through even my toughest days
    December 21, 2013
    Love it!
    I originally bought this because my partner was suffering unbearable insomnia that was only helped by pretty intense anti-anxiety prescriptions.

    He started to take this, it took about a week to really help him. I tried it one night when I was stressed and couldn't sleep, it started working right away for me.

    We both started taking it routinely, it was like the happiness reset button.

    We'd both been under a lot of pressure, creating major stress and anxiety for a long time. We used it for about 2 weeks, then ran out. There was no detox phase, or issues when we stopped taking it (we're buying more pronto, but wanted to make sure it wasn't addictive first).
    We both took it at night. It helps to give you a nice peaceful happy feeling, no weird side effects, no crashing.

    I'd highly recommend this to anyone who's struggling with stress and anxiety.
    September 29, 2013
    Great results with this product!
    I feel like this product really helps to boost my mood and helps with appetite control. I have and will recommend this product again and again.
    November 14, 2011
    Start typing your question and we'll check if it was already asked and answered. Learn More
    Browse 7 questions Browse 7 questions and 8 answers
    Can I take 5 http and 150 mg of Zoloft together?
    Edward H on Jul 12, 2018
    BEST ANSWER: Yeah if you like taking trips to the hospital.
    does it make you drowsy?
    A shopper on Nov 5, 2018
    BEST ANSWER: I take it about 1 hr before I go to bed and zip don't seem to have a problem falling asleep. So I personally believe it does make me tired.
    I am currently taking Celebrex for my fibromyalgia, recently added Tumeric. As I have problems with depression, weight, and headaches along with fibro and its usual symptoms . Have been on Celebrex for 10 plus years, can I replace it with 5HTP.?
    A shopper on Aug 22, 2013
    BEST ANSWER: The GNC website even says to consult with a professional health care practitioner before making any health decisions. Natural Database says 5-HTP "can reduce pain associated with fibromyalgia" if taken 3 times per day. In the end, you have the ultimate decision.
    How long does it take before u start noticing a difference in the way u are feeling? i do take Cymbalta and Imitrex but would like to add this to increase my seretonin levels. Does anyone know how long it takes before u start noticing the effects? Thank you.
    A shopper on Oct 14, 2012
    BEST ANSWER: It should take 12 hours to start noticing the effects. You should contact a healthcare professional before using this product since you are already taking over medications.
    My chiropractor has me taking 300mg a day, I suffer with migraines 3-4 a wk, & I'm on Effexor,imitrex,,& Valium so what should be careful about?
    A shopper on Sep 27, 2012
    BEST ANSWER: The recommended dose on the label is no more than 200 milligrams per day.
    How do you know if the 100mg or 200mg should be take since both are available?
    A shopper on Feb 19, 2012
    BEST ANSWER: If you're taking it on the advice of a health care professional, then take the dosage he or she recommends. Otherwise, it's probably most advisable to start with a lower dose to see how you respond to it. If you don't notice any affects you could increase the amount you take. I think there's even 50 mg capsules available.
    What is the best time of day to take 5-HTP?
    A shopper on Dec 5, 2011
    BEST ANSWER: The active ingredients in Natrol 5-HTP 100mg Time Release are released over a 12-hour time frame so it is best to take the pill in the morning when you first get up.