Appetrex Control™ | GNC
Gluten Free Gluten Free
Dairy Free Dairy Free
Soy Free Soy Free
Sodium Free Sodium Free
No Preservatives No Preservatives

GNC Total Lean® Appetrex Control™


Item # 978221
Gluten Free Gluten Free
Dairy Free Dairy Free
Soy Free Soy Free
Sodium Free Sodium Free
No Preservatives No Preservatives
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Note: This product cannot be sold in California

Product Information



You’re committed to looking and feeling your best, but sometimes you need a little help—we’re committed to helping you get there. Appetrex Control™ is a dietary supplement that provides clinically studied results you can count on. GNC Total Lean® products were created to help you take control of your weight loss goals, focus on your health and still be totally you.


  • Shown to reduce calorie intake^*
  • Fuels energy & metabolism*
  • Enhances mental focus*


^In a clinical study of 30 healthy adults (who took Appetrex Control™ one week followed by a placebo one week apart, or vice versa), calorie intake was reduced by nearly 10% when the subjects took Appetrex Control™ versus the placebo prior to their first meal at the start of their diet.


Nutrition Facts
Serving Size  2 Tablet(s)
Servings Per Container  30

Amount Per Serving     % DV

Calcium 141mg   11%
Chromium (as Hydrolyzed Protein Chelate) 120mcg   343%
Thiamin (vitamin B1) (as thiamine mononitrate) 1.5mg   125%
Riboflavin (Vitamin B-2) 1.7mg   131%
Niacin 20mg   125%
Vitamin B-6 (as Pyridoxine Hydrochloride) 2mg   118%

Appetrex Herbal Blend  522.5 mg   **
   Black Tea Leaves Extract (Camellia Sinensis)   **
   Green Tea Leaves Extract (Camellia sinensis)   **
   Green Coffee Bean Extract (Coffea canephora)   **
Yerba Mate Leaf Extract (Ilex paraguariensis)  500 mg   **
Grape Skin and Seed Extract (Vitis vinifera)  210 mg   **
Chrysin  200 mg   **
Ginger Root Extract (Zingiber officinale)  200 mg   **
Grape Seed Extract (Vitis vinifera)  125 mg   **
Dill Weed Extract (Anethum graveolens)(Aerial Parts)  5 mg   **

** Daily Value (DV) not established.
Other Ingredients
Dicalcium Phosphate, Microcrystalline Cellulose, Maltodextrin, Croscarmellose Sodium, Crospovidone, Stearic Acid Vegetable Source, Hydroxypropyl Methlycellulose, Calcium Silicate, Magnesium Stearate Vegetable Souce, Polyethylene Glycol, Polysorbate 80, Vegetable Acetoglycerides, Caramel Color, Ethyl Vanillin, Titanium Dioxide (Mineral Whitener)
Label (click image to enlarge)

How To Use

As a dietary supplement, take two tablets once daily with water 30 to 60 minutes before lunch or dinner. Do not take near bedtime.
Consult your physician prior to using this product if you are pregnant, nursing, taking medication or have a medical condition. Discontinue use two weeks prior to surgery. , This product contains EGCG from green tea.
Keep out of reach of children., Store in a cool, dry place away from light.
Distributed by:
General Nutrition Corporation
Pittsburgh, PA 15222 USA


4.0 / 5.0
199 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Star
Ive been taking this for 5 days and i still feel very tired and im always still hungry! When is this suppose to start working???
June 27, 2019
Week two and it seems to help suppress my appetite.
May 31, 2019
2 months ago
works for me
I take this early in the morning it really works for me. i work third shift so it helps me to fast while i work. The mental clarity is amazing it help me stay focused and alert no jitters ever. great product
May 26, 2019
Not noticing the appetite control I was looking for. There are other GNC weight control I would go back to.
May 10, 2019
2 months ago
I wish it worked better but still giving it a chance.
I bought this in conjunction with the mango-orange drink it hopes of curbing my appetite. It's not working as I would have liked it to but I am going to keep trying until I have finished the product. I usually take it at noon or just before noon in hopes of eliminating the mid-afternoon cravings. Not that much luck. Some days are OK while other days it has no effect.
May 5, 2019
3 months ago
Doing the job slowly
May 1, 2019
2 months ago
This product did not work for me it gave me an appetite didn’t give me the support I needed to not eat at different times of the day.
April 28, 2019
2 months ago
So far it has been a good investment
I have been using it for almost a week now and it really gives me a fullness feeling that helps me avoid cravings. I look forward to see the results on the next few weeks.
April 13, 2019
3 months ago
This actually works
My husband and I have been taking appetrex for a month now, which has helped us to stick with our meal prep. No more snacking around. Appetite has gone down for the both of us and we have energy throughout the day. Do not take these on an empty stomach.
March 28, 2019
4 months ago
Recommend- this product helps not eat between meals. I eat less sweets through the day or non at all. Sweets are my biggest problem.
March 22, 2019
4 months ago
Start typing your question and we'll check if it was already asked and answered. Learn More
Browse 96 questions Browse 96 questions and 85 answers
Why did you choose this?
GNC Store
It has ingredients I was looking for
Patricia D on Apr 2, 2015
It has ingredients I was looking for
Patricia D on Apr 2, 2015
loos weight
c r on Apr 2, 2015
loos weight
c r on Apr 2, 2015
does this product keep you up in the night or make you jittery?
A shopper on Jun 20, 2011
BEST ANSWER: Yes it does. It gave me insomnia so bad I had to stop taking it and I plan to return it.
As a dietary supplement, take ONE tablets TWICE A daily with water 30 to 60 minutes before lunch AND dinner OR take two tablets once daily with water 30 to 60 minutes before lunch or dinner.
A shopper on Jun 3, 2013
BEST ANSWER: i take mine early i wouldnt recommend you take any late in the day because it will affect your sleep
Can I take this along with a B-12 supplement?
A shopper on May 5, 2016
BEST ANSWER: yes. I do
Is this product safe if you have high blood pressure and already taking medication for the HTN? I see no answer has been answered when this question was previously asked.
A shopper on Jul 12, 2012
BEST ANSWER: It is not recommended that you take GNC Control ACS™ Appetite Control Support, while you are on any kind of medication unless approved by your physician.
Is it OK to take this product along with the GNC total lean 60?
A shopper on Nov 21, 2013
BEST ANSWER: GNC Total Lean 60 is a thermogenic, it should not be stacked with other appetite suppressant formulas.
Can I take CLA Thermo and Appetite Control at the same time?
A shopper on Oct 17, 2013
BEST ANSWER: Yes, you can take the GNC Control Appetite Control Support and CLA Thermo together.
hello i was wondering if this product contains any illegal drugs because i work on a sensitive are and i get drug test often
A shopper on Jan 12, 2012
BEST ANSWER: This supplement does not contain any illegal drugs.
Can i take this product early in the morning with an empty stomach?
A shopper on May 4, 2016
Is this okay to take with gnc womens ultra mega energy and metabolism multivitamin?
A shopper on Apr 25, 2016
hi, i am on thyroid medicaine should i take this?
terry on Apr 30, 2018
I am on a antidepressant, is this medication ok to take?
A shopper on Oct 27, 2016
BEST ANSWER: I take Effexor and this, and have no problems!
A shopper on May 11, 2016
BEST ANSWER: label specifically does not state caffeine. however some ingredients that are listed do have caffeine in them. product does not make me gittery and i am very sensitive to caffeine but I do recommend not to take it after 4 .pm.
If my appetrex has an expiration date of December 2012, can I still use it-if it was stored properly and still looks like it in great condition?
A shopper on May 22, 2013
BEST ANSWER: No, the product should be discarded.
Does the product Appetrex Control contain saffron or a form of it in its ingredients
A shopper on Mar 14, 2012
BEST ANSWER: This product does not contain any form of saffron.
Is there any caffeine or ephedrine in this product?
A shopper on Jan 11, 2017
BEST ANSWER: Appetrex Control contains 180 mg of caffeine per serving.  It does not contain ephedrine.  Appetrex Control should be taken as directed on the product label.
Are you supposed to take one before lunch, and one before dinner (adding to a total of 2 daily) ? Or are you supposed to take 2 at the same time, either before lunch or dinner, whichever one prefers ?
A shopper on Sep 5, 2013
BEST ANSWER: No not two dose times, only one dose a day. You should take 2 at the same time either before lunch or dinner.
Does anyone have trouble sleeping if they take this before dinner? Since there's caffeine in it.
A shopper on May 16, 2019
BEST ANSWER: This medication even though it does not have caffeine in it gave me palpitations and night mares. I stopped taking it after 3 days.
Does product increase heart rate or give you jitters?
A shopper on Apr 5, 2019
BEST ANSWER: Not at all. How ever, I'm very resistant to caffeine and stimulants
Does this product upset your stomach or cause stomach pain?
A shopper on Feb 22, 2017
BEST ANSWER: We are unable to state any side effects since products can effect people differently. If you are receiving these types of effects, stop use of product.
Is this product safe if you are taking Ritalin?
A shopper on Jan 19, 2012
BEST ANSWER: The product label on GNC Control ACSâ„¢ Appetite Control Support requires that you contact your doctor before using this product if you are taking any kind of prescribed medications. So until you consult with your doctor it is not safe to use this product with Ritalin.
can I take this product with CLA?
A shopper on Apr 14, 2012
BEST ANSWER: Yes, you can take this product with CLA. You may also want to consider taking a fiber supplement as part of a more complete and effective weight loss regimen.
Is it safe to take while breastfeeding?
A shopper on Apr 21, 2019
BEST ANSWER: Personally I would not recommend taking this while breastfeeding as it could cause side effects. The bottle itself recommends consulting a physician prior to using if you are pregnant or nursing.
Where is this item made at?
A shopper on Mar 16, 2017
BEST ANSWER: Greenville, SC.
Can you take this with the GNC SuperFoods Apple Cider Vinegar Complete?
A shopper on Feb 17, 2017
Is this product kidney friendly?
Richard G on Feb 12, 2017
BEST ANSWER: We would recommend speaking with your doctor.
im drinking pills for highblood can I use the control pills?
A shopper on Jan 18, 2017
BEST ANSWER: We would recommend speaking with your doctor.
Is there an over the counter equivalent to adipex?
A shopper on Jan 13, 2017
BEST ANSWER: We would recommend speaking with your doctor.
Can you take it with CLA?
A shopper on Dec 21, 2016
BEST ANSWER: Yes, this product can be taken with CLA.
Can i take with prozak ?
A shopper on Aug 31, 2016
Hello, can this item be purchase from your store?
A shopper on Jun 29, 2016
BEST ANSWER: yes it can