Instaflex® Joint Support | GNC
Note: This product cannot be sold in Canada

Product Information



Instaflex™ Joint Support is a revolutionary joint health formula that has been scientifically formulated to support healthy joints.* Featuring an exclusive compound of eight key ingredients that have been clinically tested for maximum effectiveness. Use Instaflex™ daily for happy, healthy, active lives.

  • Relieve Discomfort*
  • Improve Flexibility*
  • Increase Mobility*


Nutrition Facts
Serving Size  3 Capsule(s)
Servings Per Container  30

Amount Per Serving     % DV

Glucosamine Sulfate  1500 mg   **
Methylsufonlylmethane (MSM)  500 mg   **
White Willow Bark Extract (standardized to 15% Salicin)  250 mg   **
Ginger Root Concentrate 4:1  250 mg   **
Boswella Serrata Extract (Standardized to 65% boswellic acid)  125 mg   **
Turmeric Root Extract  50 mg   **
Cayenne 40m H.U.  50 mg   **
Hyaluronic Acid  4 mg   **

** Daily Value (DV) not established.
Other Ingredients
Rice Flour, Gelatin, Vegetable Magnesium Stearate, Silicon Dioxide
Label (click image to enlarge)

How To Use

As a dietary supplement, take 3 capsules daily with water. For best results, light exercise and sensible diet are recommended.

Use only as directed. Consult a health care practitioner before use if you are pregnant or nursing, allergic to aspirin, have a serious medical condition or use prescription medications. For adult use only.

Direct Digital LLC
508 West 5TH Street #250
Charlotte , NC 28202


4.5 / 5.0
159 Reviews
5 Stars
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1 Star
Auto ship alert. free 2 week sample=Auto charge at inflated price
The product is good I felt it helped. I also felt robbed when I finished the 2 week trial and $80.41 cents was withdrawn from my checking acct to pay for a 30 day supply I did not order. A 60 day supply is sold on the website for $59.99. I would have ordered it if treated fairly now I'm so mad I have no intention of ordering it and being overcharged. PS when I called the best their sassy operator offered me was a $35 credit. I am on a fixed income and an $80 withdrawal mid month is tragic for me.
February 9, 2019
Never arrived...
Never arrived...
June 20, 2018
1 year ago
I have been taking Instaflex for a while and do notice that my joints are not as painful. Pain is not completely gone, but sure is better.
June 12, 2018
1 year ago
I've only been taking it for5 days and it has helped me already. I would recommend this to anybody.
June 11, 2018
Insta Flex Joint Support is right for us!
We love Insta Flex Joint Support. I don’t let it run out because I can tell I ache more. I can stay more flexible with it. I take 1 2x daily.
May 30, 2018
1 year ago
This is the form of Instaflex that I prefer. You have an updated, modified version in your store that does not have half the ingredients that this does. This version really works, and I hope you continue to stock it and sell it.
April 10, 2018
1 year ago
Read carefully terms and conditions- RIP OFF
I ordered free sample and in the mean time had to travel to Europe for business. When I came back my wife told me that I received 3 more bottles. When I checked my bank account there was a surprise...gave them a gift of $210. Be smarter than me. By the way it didn't work on my foot at all had to go with oils and noticed huge difference.
February 12, 2018
Let see 2 weeks the same your commercial Thanks
I just drank 3 days my knees feel look like wearing heat pad
February 4, 2018
1 year ago
Instaflex did not help me.
I took the capsules as directed and have not had much relief.I do not want to continue so please put a stop on future orders. send me a letter stating I have been stopped. Sharlene Gill
January 22, 2018
Less knee pain
Iâ??ve been taking it for 2 weeks and my knees are starting to feel better!
December 27, 2017
1 year ago
Start typing your question and we'll check if it was already asked and answered. Learn More
Browse 98 questions Browse 98 questions and 104 answers
my knees are already bone on bone will this product help me?
A shopper on May 7, 2012
BEST ANSWER: I have bone on bone and it helps me.
When I take Instaflex with meal or not?
A shopper on Jun 28, 2012
BEST ANSWER: This Instaflex Joint Support supplement does not need to be taken with a meal.
I am taking Instaflex Advanced. What ingredients could be making my throat sore and my glands in my throat swell?
Eleesa H on Sep 7, 2016
BEST ANSWER: The Instaflex I have been taking is the regular not the Advanced. I have been taking regular Instaflex for 4 or 5 years and never had any problems with it. I think this is a wonderful product, I can't imagine not having it for the pain in my (knees). The problems you are having should be checked by your physician. Good Luck!!
What if any RX meds I take would preclude taking Instaflex?
A shopper on Jan 14, 2012
BEST ANSWER: As the ingredients in Instaflex are all natural, there are no known prescription conflicts that would prevent you from taking the supplement.
Many of the comments stated that it took sometime to kick in -
thus would you give a guarantee for 60 days if I were to try Instaflex ?
A shopper on Jun 5, 2012
BEST ANSWER: Unfortunately, GNC only has a 30 day money back guarantee, not a 60 day guarantee. This is only a 30 day supply of the supplement (directions state to take 3 capsules a day, with 90 in the bottle) so if taken as directed, you'd have finished the supplement far before 60 days.
Does your product contain vitamin K,I take Coumadin for blood thinner.Vitamin K , I am told counteracts my medication.
A shopper on Apr 22, 2012
BEST ANSWER: Instaflex Joint Support does not contain Vitamin K.
is this product gluten free since i am gluten intolerant..
A shopper on May 2, 2013
BEST ANSWER: Yes, this product is gluten-free.
How long is its shelf life?
A shopper on Aug 13, 2012
BEST ANSWER: The shelf life for this supplement is 3 years from date of manufacture. Generally it is delivered with a minimum of 12 months until the expiration date.
Can this be used for male over 80 years old?
A shopper on Aug 4, 2012
BEST ANSWER: This product is for adults of all ages, but it is recommended that you consult your physician before using if you take prescription drugs, are allergic to aspirin or have a serious medical condition.
I have a history of ulcers and have high blood pressure. Will this product cause stomach upset or cause problems with blood pressure?
A shopper on Jan 6, 2014
BEST ANSWER: This is a all natural product and should not interfere with either of your problems, if still unsure discuss it with your doctor and do let him/her know you have started this.
Does the advance have aspirin in it?
Johnsie A on Feb 26, 2018
BEST ANSWER: No aspirin in Instaflex Advanced.
How many a day do you take?
A shopper on Nov 10, 2016
BEST ANSWER: I only take 2, one with breakfast 1 in the afternoon.
is it good for joint pains on the hands?
A shopper on Feb 12, 2017
BEST ANSWER: I have pain on my hands too. I'm sure it would hurt more if I stop taking instaflex.
what,s the dosage per day??
A shopper on Jan 4, 2012
BEST ANSWER: The daily dosage is 3 pills per day.
Where is this product made?
A shopper on Dec 10, 2018
BEST ANSWER: Excellent Thank you very much
If this product is all what you say it is, why charge so much? Its only to help you not the people that needs it.
A shopper on Aug 12, 2018
BEST ANSWER: Instaflex works and is worth the money!
Does this product contain any shellfish?
A shopper on Apr 8, 2014
BEST ANSWER: Instaflex contains glucosamine, a substance derived from shellfish.
How many capsules do I take a day?
A shopper on Jan 19, 2014
BEST ANSWER: You take 3 capsules daily. All can be taken at once.
what is the expiration period of this product?
A shopper on Dec 4, 2013
BEST ANSWER: Joint support products will maintain at least 90% efficacy for 3 years after purchasing and opening the product.
I have what has been labeled as "sticky atlas". My atlas joint pops when I turn or bend my head. Will this product give me any relief? Thanks
A shopper on Nov 20, 2013
BEST ANSWER: The Direct Digital Joint Support is a supplement to relieve discomfort, increase flexibility and increase mobility.
my blood sugar is high, can I take this suplement?
A shopper on Nov 17, 2013
BEST ANSWER: Since you have high blood sugar only your medical professional can properly advise you if you can use the Instaflex Joint Support supplement.
Do I take the 3caps in one shot?
A shopper on Nov 15, 2013
BEST ANSWER: Yes, you can take the 3 caps at one time.
what is the difference between Instaflex and Tfxflex for joint discomfort?
A shopper on Aug 30, 2013
BEST ANSWER: They are different brands which treat the same issue.
How many capules a day are needed to maintain the best results.
A shopper on Aug 7, 2013
BEST ANSWER: The recommended dose on the package is 3 capsules a day. So for the best results would be 3 a day.
Can you use this product If you have a back problem, like Sciatic nerve? Or any kind of back pain or body pain?
A shopper on Jul 29, 2013
BEST ANSWER: Yes you can use this if you have back pain.
Can this be used for people who suffer from gout and get relief from this product?
A shopper on Jul 18, 2013
BEST ANSWER: Yes, people with Gout have used this product
does this product contain any calcium?
A shopper on Jun 18, 2013
BEST ANSWER: The product does contain calcium.
I have a partial tear of my shoulder-rotator cuff...I see all comments discussing better flexability for knees. Can anyone tell if Instaflex will help my shoulder?
A shopper on Jun 17, 2013
BEST ANSWER: Yes, it is meant to help all joints.
I am a muslim, living in Pakistan. I would like to ask that what is the source of the gelatin used in Instaflex?

Is it halal?

Thank You.
A shopper on Jun 4, 2013
BEST ANSWER: No Instaflex Joint Support is not certify as halal. The gelatin is from FDA inspected facilities and can be from either bovine (cow) or pork sources.
How many pills would you take a day?
A shopper on Jun 1, 2013
BEST ANSWER: The recommended dosage is three capsules per day.