SAM-e 200 MG | GNC

GNC SAM-e 200 MG


Item # 130422


Size: 30 Enteric Coated Tablets

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GNC SAM-e 200mg: Improves Positive Mood Balance, Joint Health & Liver Function
GNC SAM-e dietary supplement offers support for joint health and liver function. Its active ingredient may provide mood balancing benefits. Studies published by the U.S. Department of Health and Human Services suggest SAM-e may help support joint discomfort. The SAM-e molecule is naturally produced in the body. Research indicates that individuals who don't make enough of the substance naturally might benefit from supplementation.  


• SAM-e 200mg to improve joint discomfort
• May support positive mood balance
• Provides liver function support


Nutrition Facts
Serving Size  1 Tablet
Servings Per Container  30

Amount Per Serving     % DV

SAM-e (S-adenosyl-methionine) (as Disulfate Monotosylate)  200 mg   **

** Daily Value (DV) not established.
Other Ingredients
Core: Microcrystalline Cellulose, Mannitol, Sodium Starch Glycolate, Silica, Glycerol Monostearate., Coating: Methacrylic Acid Copolymer, Glycerol Palmitostearate, Medium Chain Triglycerides, Titanium Dioxide, Silica, Talc, Triethyl Citrate, FD&C Yellow #5
Label (click image to enlarge)

How To Use

As a dietary supplement, take one tablet in the morning and one table in the afternoon for the first week. If after the first week the desired benefits are not achieved, then you may require a higher level of supplementation. Gradually increase the number of tablets up to eight tablets in divided doses of two tablets (400 mg) throughout the day until benefits are achieved. Do not exceed eight tablets daily.
Do not use if pregnant or nursing. Do not exceed recommended dose. If you are taking medication or are under the care of a physician for depression or related disorder, contact your physician before using this product. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use. Caution: Do not use if tamper-evident printed foil seal over tablets is broken.
Distributed by: General Nutrition Corporation Pittsburgh, PA 15222


4.6 / 5.0
8 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Star
I take the 200mg and find it works perfectly!
Works, helps me focus while reading and helps me maintain focus. Also helps me start and finish daily task. I noticed after I started taking this im much more able to take down notes and numbers at work much more efficiently without struggling.
February 6, 2019
2 months ago
I always order only from GNC, it the best brand.
August 27, 2018
8 months ago
Excellent treatment for my depression
I've been diagnosed with severe depression. My doctor put me on SSRIs, but the side effects were unbearable. After getting off them, I decided to try SAM-e and found it to be much more effective with very few side effects.
August 3, 2017
Used to buy all the time
A few years back they changed the formulation and added mannitol. I went from years of use to extreme stomach pains and bloating. Mannitol is what does this. I check back every now and again to see if they changed their formula back and they haven't. Its a shane because this really worked and was affordable.
July 19, 2016
SAM-e 200 mg
Was recommended by my MD. I take it daily. Easy to take but is expensive.
July 3, 2014
Works great
Great product
April 22, 2014
great product!
I cannot believe the difference this product has made in my life. Not only did it help my moods, but no more pain in my knees!! Highly recommend. I am small person so I take 200 mg once per day. I have used other brands but GNC brand seems to work the best!
July 23, 2013
Easy on stomach
this doesn't irritate the stomach like other brands
July 20, 2013
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Browse 4 questions Browse 4 questions and 2 answers
I cant take sam-e with mannitol because it is terror on my stomach. do you have product without mannitol?
A shopper on Oct 16, 2016
I currently take an antidepressant - Effixor. Is it ok for me to also take SAM-e for joint pain that I am experiencing?

Thank you.
A shopper on May 1, 2013
BEST ANSWER: Contact your doctor before taking both at the same time. I can't give medical advice.
This is the best formulation of Sam-e by far but can you please make Sam-e without mannitol? I haven't been able to buy since you added it.
AC on Sep 3, 2018
BEST ANSWER: What is mannitol?
is there talc in this product?
A shopper on Apr 19, 2016