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Last Updated: March 2, 2026

GlucaTrim – A Q&A Sesh With The Product Formulator

By Mary Milstead |
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Mary Milstead MS, RD, LDN
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When it comes to learning the ins, outs, and science behind an innovative product, there’s no one better to do a deep dive than the brains behind the bottle… the product formulator! 

GNC Total Lean® GlucaTrimis now even better. We listened to your feedback and are relaunching the latest and greatest weight loss supplement. GlucaTrim (and GlucaStim – the all new stimulant version) was formulated by Dr. Lauren Green. Lauren has been an integral part of GNC’s Scientific Affairs & Research & Development teams since 2013. She is a Registered Dietitian with Bachelor’s, Master’s, and Doctorate degrees in Nutrition as well as a Certified Personal Trainer. As a figure competitor and powerlifter, she not only talks the talk, but walks the walk. 

We sat down with Lauren and asked her what makes GlucaTrim so special.

Dr. Lauren Green, DCN, RDN, LDN, CPT

The Formulator of GNC Total Lean GlucaTrim. Read her bio here!

What is GlucaTrim?

GNC Total Lean® GlucaTrim is a dietary supplement with proven, multi-action support that works with your body to support weight loss, healthy blood sugar and insulin levels, hunger and appetite control, and lean mass protection. It offers ingredients clinically proven to help you lose nearly 12 lbs^, drop pounds, lose inches, and support healthy blood sugar levels when used in conjunction with the recommended diet and exercise plan.

Do any supplements really work for weight loss?

That’s a complex question because not all supplements are created equalIt’s always important to follow a healthy, reduced-calorie diet and exercise plan when trying to lose weight but adding in select supplements can also help you along the way. When in doubt, you can trust the quality behind GNC products because our team of nutrition experts painstakingly reviews the science behind every ingredient. We then use that knowledge to formulate science-based solutions to ensure they give you the results you’re looking for. 

How does GlucaTrim work?

GlucaTrim is a multi-action product, which means it was designed to work in a few different ways. The key areas that GlucaTrim addresses are the following: 

  • Enhances Metabolism & Burns Fat 
  • Reduces Hunger & Cravings 
  • Supports Healthy Blood Sugar Levels 
  • Protects Lean Muscle 
  • Reduces Inches From Trouble Areas
Bottle of glucatrim next to it's benefits listed with bullets.

What is the connection between blood glucose and body weight?

There is a connection between blood sugar levels and body weight. Excess blood sugar and insulin levels signal the body to store the excess sugar or glucose. The body’s preferred storage unit of that excess glucose is fat. High blood sugars and insulin levels can therefore contribute to a potential for increased fat storage, which can make losing weight more difficult. 

Why did you choose the ingredients in GlucaTrim?

I chose the ingredients in GlucaTrim based on scientific evidence. 

    • Slimvance® – Slimvance is a combination of moringa, curry, and turmeric. It’s been clinically proven to help people lose nearly 12 lbs, with results starting in just two weeks. It also helps users lose inches from the waist and hips, protects against lean mass loss, and supports metabolism during weight loss^. 
    • Reducose® – Reducose is a white mulberry leaf extract shown in clinical research to support the optimal balance of blood glucose and insulin after a meal. 
    • Chromax® – Chromax is a premium form of chromium picolinate and has been shown to protect lean mass, including muscle, and support healthy glucose and insulin levels. 
    • DNF-10® – DNF-10 is a clinically studied hydrolysate peptide, shown to help you eat less, reduce feelings of hunger, and cut down on cravings for sweets. 
    • Ginger – Ginger was added to the new GlucaTrim formula to provide natural digestive support. 
    • Natural Caffeine (GlucaStim only) – To deliver an immediate energy and metabolism boost. 

Does GlucaTrim contain caffeine?

Is there a stimulant option?

No, GlucaTrim provides all its great benefits without the addition of caffeine! We also worked really hard to make sure GlucaTrim is vegetarian, gluten free, and free from artificial colors and flavors.  

GlucaStim on the other hand provides the same ingredients you’ll find in GlucaTrim, plus 150 mg of natural caffeine for all you stimulant lovers out there! We wanted to provide a total weight loss support system, and by adding the GlucaStim option, you can now enjoy an additional boost of energy in the mornings with your breakfast meal or before a workout. GlucaTrim can be used any time of day! 

When Should You Take GlucaTrim?

When Should You Take GlucaStim?

GlucaTrim should be taken twice daily with your two largest meals. This is primarily due to the action of Reducosewhich helps to support balanced blood sugar and insulin levels after meals. Taking GlucaTrim with meals can also be a great way to remember to consistently take it! 

GlucaStim should also be taken with your two largest meals of the day. We recommend choosing GlucaStim with your breakfast, lunch, or prior to activity. It contains 75 mg of caffeine per dose so plan accordingly – especially if you’re sensitive to caffeine. GlucaTrim would be a better choice if one of your largest meals is at dinnertime. We don’t want to disrupt sleep, which is also an important piece of weight management! 

Do You Have Any Recommendations on A Diet and Exercise Plan?

I recommend the healthy meal and exercise plan available at gnc.com/live-total-lean. If you need any more help or direction, I recommend reaching out to a dietitian who can help give you more specific diet recommendations.

What other products should I take to help me lose weight?

When trying to lose weight, protein should be your best friend. A great place to start is a meal replacement, such as Lean Shake 25. Just replace 1-2 meals per day with a shake. You can also incorporate protein powders, bars, and snacks throughout the day.  

^ A 16-week randomized clinical study of 140 healthy, overweight people compared the use of Slimvance® with an 1,800-calorie diet & walking plan to a placebo with the same diet & walking plan. Those on Slimvance® lost a statistically significant amount of weight, 11.81 pounds, while the placebo group lost 1.91 pounds vs. baseline. The Slimvance® group saw weight loss results in as soon as 2 weeks. Use in conjunction with the Total Lean® diet & exercise program at www.gnc.com/live-total-lean. 
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. 

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